Most children with a severely broken wrist can be treated without surgery, according to a major UK trial led by researchers at the University of Oxford. The findings of the CRAFFT trial, which was funded by the National Institute for Health and Care Research (NIHR) and supported by the NIHR ... READ MORE
Rapid development of Oxford COVID vaccine and set-up of RECOVERY trial praised by COVID Inquiry
The UK’s COVID Inquiry has praised the speed with which the Oxford/AstraZeneca COVID vaccine was developed and the rapid set-up of the Oxford-led RECOVERY trial, which identified the first effective treatment for COVID. The Inquiry was publishing its fourth report, this one on vaccines and ... READ MORE
Oxford plays key role in new national transplant programme
An Oxford BRC researcher is playing a leading role in a new national NHS programme to use machine perfusion to preserve and assess organs for transplantation. Professor James Hunter, Associate Professor of Transplant Surgery and lead for the Oxford BRC surgical sub-theme looking at organ ... READ MORE
OUH healthcare professionals’ research career pathway boosted with new Clinical Lectureships
Four Oxford University Hospitals (OUH) health and care professionals have become the first to be awarded a new Academic Clinical Lectureship, to be based in the Oxford University Clinical Academic Graduate School (OUCAGS). The new Academic Clinical Lectureship is aimed at providing a clear ... READ MORE
New AI tool can predict heart failure at least five years before it develops
A pioneering artificial intelligence (AI) tool can predict a person's chance of developing heart failure at least five years before the debilitating condition develops, according to new research supported by the NIHR Biomedical Research Centre: Oxford and the BHF. The research team from the ... READ MORE
Workshop explores how to translate remote monitoring into clinical practice
Researchers from several NIHR Oxford Biomedical Research Centre (BRC) themes came together to discuss how they are using wearable technologies in their research and what need to happen to allow this remote monitoring to be implemented in everyday clinical practice. Among the aims of the ... READ MORE
Long‑term fall in pneumothorax deaths stalled by COVID pandemic, study shows
New research has found that deaths linked to spontaneous pneumothorax had been steadily falling in England for more than 15 years, but this progress was disrupted during the COVID‑19 pandemic. Spontaneous pneumothorax is the development of a tiny tear in the outer part of the lung. This causes ... READ MORE
Two Oxford BRC researchers named NIHR Senior Investigators
Two Oxford Biomedical Research Centre (BRC) researchers have been named among the latest cohort of National Institute for Health and Care Research (NIHR) Senior Investigators. Paul Leeson, Professor of Cardiovascular Medicine, and Najib Rahman, Professor of Respiratory Medicine, received the ... READ MORE
Oxford University signs agreement to advance Nipah vaccine candidate
The University of Oxford and Serum Institute of India (SII), the world’s largest vaccine manufacturer, have signed an intellectual property licensing agreement to advance the development and manufacture a vaccine candidate for the deadly Nipah virus. Under the terms of the agreement, SII has been ... READ MORE
Ensuring frail older patients’ voices are heard in our research
We want to be sure that our current and future research is relevant and focuses on what matters most to those who need it. It’s therefore vital that patients, carers and members of the public are encouraged to get involved in that research. Nowhere is this more relevant than in research that aims to ... READ MORE
New research reveals why some oesophageal cancers are hard to treat
Researchers in Oxford have uncovered new insights into why the most aggressive oesophageal cancers are so difficult to treat and how the body’s own defence systems are helping them to thrive. The study, led by Professor Eileen Parkes in the University of Oxford’s Department of Oncology, ... READ MORE
New AI model could improve heart monitoring in hospitals and at home
Researchers have developed a new artificial intelligence (AI) model that could significantly improve how heart conditions are detected, monitored and managed — whether in intensive care units or in people’s own homes. Heart disease remains one of the leading causes of death worldwide. ... READ MORE
OUH receives over £1m for vital research equipment
Oxford University Hospitals (OUH) has received more than £1 million to fund state-of-the-art equipment to expand its research capabilities. The funding was awarded after a competitive process by the National Institute for Health and Care Research (NIHR) as part of its capital funding to NHS ... READ MORE
‘Hidden’ cost of social care after hip fracture exceeds £1.25bn a year in UK, study estimates
Social care following hip fractures costs more than £15,000 per patient every year, according to a new study by Oxford researchers. This amounts to a total cost of £1.25 billion per year. Hip fracture is the most common serious injury in older adults, affecting over 80,000 people in the UK ... READ MORE
Drugs identified that could help prevent delirium after surgery
A new study has found that several commonly used drugs could significantly reduce the risk of delirium in older people following surgery. Delirium – a sudden state of confusion and memory problems – affects around one in seven older adults after an operation. People who get delirium spend ... READ MORE
Study warns of risks in AI chatbots giving medical advice
The largest user study of large language models (LLMs) for assisting the general public in medical decisions has found that they present risks to people seeking medical advice due to their tendency to provide inaccurate and inconsistent information. The research reveals a major gap between the ... READ MORE
Study tests whether deep brain stimulation can treat chronic pain
The first three patients have undergone revolutionary brain surgery in a bid to treat the chronic pain they have experienced since suffering a stroke. A research study by Oxford neurosurgeons and engineers is trialling whether deep brain stimulation (DBS) – delivering an electrical pulse into ... READ MORE
New Kadoorie Institute for Trauma, Emergency and Critical Care established
Oxford Trauma and Emergency Care at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), along with the Critical Care Research Team at the Nuffield Department of Clinical Neurosciences (NDCN) have formally become a new institute within the University of ... READ MORE
Surgery unnecessary for elbow fractures in children, new study finds
Researchers in Oxford and Liverpool have found that surgery for a common elbow fracture in children offers no clinical benefit compared to non-surgical care. The findings could have significant implications for treatment and offer significant cost savings to the NHS. Published in The Lancet, ... READ MORE
Public contributors make recommendations for involving underserved communities in research
A group of patient and public involvement contributors have developed some key recommendations for researchers when engaging with under-served communities, including ensuring that the right people were involved, building relationships and being mindful of practicalities, such as payment and ... READ MORE
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