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Research Theme

Gastroenterology and Mucosal Immunity

You are here: Home > News listings for Gastroenterology and Mucosal Immunity

News for Gastroenterology and Mucosal Immunity

Oxford researchers release cheap, quick COVID-19 antibody test

29 March 2021 · Listed under COVID-19, Gastroenterology and Mucosal Immunity

An international research team led by Oxford University scientists has developed a portable test for antibodies that fight the novel coronavirus that causes COVID-19. The test, which spots the presence of virus-fighting antibodies rather than a coronavirus infection, can be adapted to work on blood from a finger prick, making it quick and easy to … Read more

New study finds strong immune response following COVID-19 vaccination

26 March 2021 · Listed under Antimicrobial Resistance and Modernising Microbiology, COVID-19, Gastroenterology and Mucosal Immunity, Vaccines for Emerging and Endemic Diseases

A new study has found that 99% of people generate a robust immune response against COVID-19 after just one dose of the Pfizer vaccine, and that after two doses levels of protection were even stronger. The PITCH (Protective Immunity from T cells to COVID-19 in Health workers) study, led by Oxford and Sheffield Universities with … Read more

Oxford academics named NIHR Senior Investigators

3 March 2021 · Listed under Gastroenterology and Mucosal Immunity, Musculoskeletal, Other News, Surgical Innovation and Evaluation, Technology and Digital Health, Vaccines for Emerging and Endemic Diseases

Four academics supported by the NIHR Oxford Biomedical Research Centre have been awarded a prestigious national award. The University of Oxford  professors have been named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and prestigious researchers funded by the NIHR and the most outstanding leaders of patient and people-based research within the NIHR research … Read more

Oxford collaborates with Janssen to map the cellular landscape of immune mediated disorders

16 February 2021 · Listed under Gastroenterology and Mucosal Immunity

The University of Oxford has entered into a strategic collaboration with Janssen Biotech to develop a cellular map of genes and proteins implicated across a range of immune-mediated inflammatory disorders and to characterise pharmacologically relevant therapeutic targets. Lead Oxford investigator for the project, Professor Holm Uhlig, said: “This exciting endeavour brings together a world-leading group … Read more

Paper urges use of genomics in care of monogenic IBD

5 January 2021 · Listed under Gastroenterology and Mucosal Immunity

Gastroenterology experts have had a position paper published that calls for genomic technologies to be considered an integral part of patient care to investigate patients at risk for monogenic forms of inflammatory bowel disease (IBD). The authors include a number of NIHR Oxford BRC-supported researchers. The paper, published in the Journal of Paediatric Gastroenterology and … Read more

IBD treatments do not increase susceptibility to COVID-19, study finds

23 December 2020 · Listed under COVID-19, Gastroenterology and Mucosal Immunity

Research by Oxford scientists has shown that rates of COVID-19 infection are not increased in patients with inflammatory bowel disease (IBD) who are being treated with the drugs infliximab or vedolizumab. The study data suggest there is no reason for treatment with these drugs to be stopped. The paper, published on the pre-print server medRxiv, … Read more

Using AI to improve the quality of endoscopy videos

25 November 2020 · Listed under Gastroenterology and Mucosal Immunity, Multi-Modal Cancer Therapies, Technology and Digital Health

A multidisciplinary team of researchers has developed a deep-learning framework for improving endoscopy to aid the detection of cancer and other gastrointestinal diseases. Cancers detected at an earlier stage have a much higher chance of being treated successfully. The main method for diagnosing cancers of the gastrointestinal tract is endoscopy, when a long flexible tube … Read more

Patients with cirrhosis at increased risk of death from COVID-19, study finds

6 October 2020 · Listed under COVID-19, Gastroenterology and Mucosal Immunity

An international study led by researchers at Oxford University Hospitals NHS Foundation Trust has shown that patients with cirrhosis are at increased risk of dying as a result of COVID-19. The study, published in the Journal of Hepatology, found that mortality from COVID-19 was particularly high among patients with more advanced cirrhosis (called Childs-Pugh B … Read more

Persistent immune memory of COVID-19 found in recovered patient T cells

10 September 2020 · Listed under COVID-19, Gastroenterology and Mucosal Immunity

Oxford University researchers have found that infection with COVID-19 produces a robust T cell response, including inducing T cell ‘memory’ to potentially fight future infections. The results, published in Nature Immunology, are a joint effort from the Oxford COVID-19 immunology group, led by the Medical Research Council Human Immunology Unit at the MRC Weatherall Institute of Molecular Medicine … Read more

Eight BRC projects get RCF funding

7 September 2020 · Listed under Cardiovascular, Clinical Informatics and Big Data, Diabetes and Metabolism, Gastroenterology and Mucosal Immunity, Genomic Medicine, Haematology and Stem Cells, Imaging, Molecular Diagnostics, Multi-Modal Cancer Therapies, Multimorbidity and Long-Term Conditions, Neurological Conditions, Stroke and Vascular Dementia, Surgical Innovation and Evaluation, Technology and Digital Health

Eight Oxford BRC proposals, many covering a number of themes, have been awarded NIHR Research Capability Funding (RCF) funding to take forward key areas of research. The selected projects that will be supported include: Developing a research centre devoted to urgent and acute care The creation of a state-of-the-art imaging centre; and of a new … Read more

Study maps role CD8 T cells play in IBD

3 August 2020 · Listed under Gastroenterology and Mucosal Immunity

Researchers in Oxford using an ‘atlas’ of immune cells in the human colon have found evidence of the role of CD8 T cells in inflammatory bowel disease (IBD). The findings could lead to a better understanding of how cells behave and interact in people with IBD, and could pave the way for more targeted treatments … Read more

BRC funds three further COVID-19 studies

21 April 2020 · Listed under COVID-19, Gastroenterology and Mucosal Immunity, Haematology and Stem Cells, Vaccines for Emerging and Endemic Diseases

Three more studies are being funded by the NIHR Oxford Biomedical Research Centre (BRC) to look at the way the body interacts with COVID19; these include assessing the safety of a new vaccine; the role that antibodies might play in plasma therapy; and blood biomarkers that determine adverse reactions in those that have been infected. … Read more

Common antibody test can be adapted for COVID-19, study finds

20 April 2020 · Listed under Antimicrobial Resistance and Modernising Microbiology, COVID-19, Gastroenterology and Mucosal Immunity

Research led from Oxford has found that an immunological assay commonly used to measure antibodies, antigens and proteins in biological samples can be specifically adapted to detect and quantifying COVID-19 antibodies. The investigations by the National COVID Testing Scientific Advisory Panel were co-ordinated by Prof Derrick Crook at the University of Oxford. The trial involved researchers at … Read more

Oxford researchers to play key role in fight-back against COVID-19

20 March 2020 · Listed under Antimicrobial Resistance and Modernising Microbiology, Clinical Informatics and Big Data, COVID-19, Gastroenterology and Mucosal Immunity, Partnerships for Health, Wealth and Innovation, Respiratory, Vaccines for Emerging and Endemic Diseases

Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the Oxford Vaccine Group and the University of Oxford’s Jenner … Read more

Oxford professors appointed NIHR Senior Investigators

24 February 2020 · Listed under Gastroenterology and Mucosal Immunity, Surgical Innovation and Evaluation

Four leading healthcare academics in Oxford have received a prestigious national award. The University of Oxford professors were named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and prestigious researchers funded by the NIHR and the most outstanding leaders of patient and people-based research within the NIHR research community and … Read more

Researchers identify link in the treatment of inflammatory bowel disease

13 December 2019 · Listed under Gastroenterology and Mucosal Immunity

A new study involving Oxford researchers has revealed how the anti-inflammatory cytokine IL-10 and lipid mediator prostaglandin E2 (PGE2) work together to prevent inflammatory tissue damage and maintain a healthy gut balance. Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) and ulcerative colitis (UC), are chronic painful inflammatory conditions of the gastrointestinal tract, which … Read more

Researchers find new cells that repair tissue

18 September 2019 · Listed under Gastroenterology and Mucosal Immunity

Researchers at Oxford University have discovered that a newly discovered group of cells can help repair tissues in the body. The researchers, who are supported by the NIHR Oxford Biomedical Research Centre, say these cells, which are abundant in our bodies, could be harnessed to help heal tissues and treat diseases such as infections of … Read more

Oxford patients take part in study to understand role of stress in managing Crohn’s disease

27 June 2019 · Listed under Gastroenterology and Mucosal Immunity, Technology and Digital Health

Around 60 Oxford University Hospitals (OUH) NHS Foundation Trust patients are to take part in a study to look at how wearable and mobile devices can help us to understand the relationship between stress and the symptoms of Crohn’s disease, and help to improve management of the condition. The research is part of a larger … Read more

BRC researchers elected Fellows of Academy of Medical Sciences

8 May 2019 · Listed under Antimicrobial Resistance and Modernising Microbiology, Gastroenterology and Mucosal Immunity, Vaccines for Emerging and Endemic Diseases

Three Oxford BRC-supported researchers are among eight University of Oxford scientists elected to join the prestigious Fellowship of the Academy of Medical Sciences (AMS) this year. The BRC researchers among the new Fellows are: Professor Helen McShane, Professor of Vaccinology in the Nuffield Department of Medicine, Deputy Director of the Medical Sciences Division and Director … Read more

Research identifies how the gut loses protective barrier function in IBD

27 February 2019 · Listed under Gastroenterology and Mucosal Immunity

A University of Oxford research team has used single-cell technology to identify new players in the gut epithelial barrier, the single-cell layer that forms the lining of the small and large intestine. The team from the MRC Human Immunology Unit (HIU), whose paper was published in the journal Nature, were supported by the NIHR Oxford … Read more

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Gastroenterology and Mucosal Immunity Theme

  • Introduction
  • Sub-theme 1: Molecular pathway analysis
  • Sub-theme 2: Biomarker and drug target development
  • Sub-theme 3: Experimental medicine trials
  • Projects awarded with response mode funds
  • Principal investigators
  • Constituent research institutes
  • Contacts
  • Videos for this theme
  • News for this theme
  • General News Listings

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