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Inflammation across Tissues

You are here: Home > News > News for Inflammation across Tissues

News for Inflammation across Tissues

National guidelines produced on use of genomics in treatment of IBD

10 January 2023 · Listed under Genomic Medicine, Inflammation across Tissues

National guidelines have been developed for clinicians on the use of genomics to diagnose and care for patients with monogenic inflammatory bowel disease (IBD), a group of intestinal disorders caused by variations in a single gene. The new guidelines, unveiled in an article in the Lancet ... READ MORE

Better diagnosis and treatment of autoimmune diseases a step closer

5 January 2023 · Listed under Inflammation across Tissues

A study involving Oxford researchers has outlined a way to find the crucial peptides (protein fragments) that drive autoimmunity, as well as the immune cells that respond to it. On a fundamental level, in autoimmune diseases immune cells mistake healthy cells for infected cells. Finding the ... READ MORE

Adalimumab found to be cost-effective treatment for early-stage Dupuytren’s disease

16 November 2022 · Listed under Inflammation across Tissues, Translational Data Science

Oxford researchers supported by the Oxford BRC have found that the anti-TNF treatment adalimumab is likely to be a cost-effective treatment for people affected by early-stage Dupuytren’s disease. Anti-TNF treatments interfere with the action of a protein called tumour necrosis factor (TNF) and ... READ MORE

Professor Fiona Powrie recognised in Queen’s Birthday Honours

6 June 2022 · Listed under Inflammation across Tissues

Professor Fiona Powrie, who leads the Oxford Biomedical Research Centre’s Gastroenterology and Mucosal Immunity Theme, has been honoured in the 2022 Queen’s Birthday Honours List. Prof Powrie, Director of the Kennedy Institute of Rheumatology, was appointed Dame Commander of the Most Excellent ... READ MORE

Paediatric IBD BioResource opens to support vital research

28 April 2022 · Listed under Inflammation across Tissues

A new National Institute for Health and Care Research (NIHR) BioResource aimed at investigating inflammatory bowel disease (IBD) in children has opened, with the NIHR Oxford BRC playing a key role. The new Paediatric Inflammatory Bowel Disease (PIBD) BioResource will drive research into Crohn’s ... READ MORE

Oxford BRC researchers named NIHR Senior Investigators

3 March 2022 · Listed under Inflammation across Tissues, Musculoskeletal, Respiratory Medicine, Surgical Innovation, Technology and Evaluation, Translational Data Science

Seven Oxford academics, six of them supported by the NIHR Oxford Biomedical Research Centre (BRC), have been named National Institute of Health Research (NIHR) Senior Investigators in recognition of their outstanding leadership in research. The NIHR describes its Senior Investigators as ... READ MORE

Genetic study highlights links between IBS and mental health disorders

10 November 2021 · Listed under Genomic Medicine, Inflammation across Tissues, Translational Data Science

Research funded and supported by the NIHR has revealed that symptoms of irritable bowel syndrome (IBS) may be caused by the same biological processes as mental health conditions such as anxiety. IBS is a common condition worldwide, affecting around 1 in 10 people. The condition causes a wide ... READ MORE

New therapeutic targets identified to treat inflammatory bowel disease

25 October 2021 · Listed under Inflammation across Tissues

A new study by University of Oxford researchers has identified potential new therapeutic targets for the treatment of inflammatory bowel disease (IBD), giving hope to millions of patients with ulcerative colitis or Crohn’s disease. The research team from the University’s Kennedy Institute of ... READ MORE

New atlas reveals pre-birth development of blood cells in bone marrow

29 September 2021 · Listed under Gene and Cell Therapy, Inflammation across Tissues, Oxford Blood Group

A new study has provided the most detailed analysis so far of the prenatal development of blood and immune cells in the bone marrow. The study, published in Nature, is part of the Human Cell Atlas (HCA) initiative to provide comprehensive reference maps of every cell type in the human ... READ MORE

MAIT Cell activation may play role in COVID-19 deaths, study finds

17 September 2021 · Listed under COVID-19, Inflammation across Tissues

Oxford researchers have found a correlation between deaths from COVID-19 infections and a poorly coordinated systemic immune response, as well as increased activity by Mucosal Associated Invariant T cells, or ‘MAIT cells’. A study involving Oxford BRC-supported researchers published ... READ MORE

New study launched to understand vaccine escape

26 August 2021 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics

Oxford researchers will be involved in a major new study seeking to understand why some people become infected after vaccination or prior infection while others do not Oxford BRC-supported investigators already involved in the Protective Immunity from T-Cells in Healthcare workers (PITCH) study ... READ MORE

Liver problems common among COVID-19 patients, study finds

23 July 2021 · Listed under COVID-19, Inflammation across Tissues, Translational Data Science

A study by Oxford University researchers has found that liver problems are common among patients with COVID-19. Patient data revealed that baseline hypoalbuminemia (an possible indication that the liver is producing low levels of albumin) and rising alkaline phosphatase (ALP), which can be a ... READ MORE

Latest data on immune response to COVID-19 reinforces need for vaccination

17 June 2021 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics

A new study led by University of Oxford has found that previous infection, whether it was symptomatic or asymptomatic, does not necessarily protect you long term from COVID-19, particularly against new variants of concern. The PITCH Study (Protective Immunity from T cells to COVID-19 in Health ... READ MORE

AI endoscopy enables 3D surface measurements of pre-cancerous condition in oesophagus

9 June 2021 · Listed under Cancer, Imaging, Inflammation across Tissues

Clinicians and engineers in Oxford have begun using artificial intelligence alongside endoscopy to get more accurate readings of the pre-cancerous condition Barrett’s oesophagus and so determine patients most at risk of developing cancer. In a research paper published in the journal ... READ MORE

Oxford BRC researchers named among new Academy of Medical Sciences fellows

12 May 2021 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Preventive Neurology, Translational Data Science

A number of leading researchers supported by the NIHR Oxford Biomedical Research Centre are among 50 prominent biomedical and health scientists elected to the Academy of Medical Sciences’ respected and influential Fellowship. The new Fellows include Oxford BRC experts who have spearheaded the ... READ MORE

Oxford researchers release cheap, quick COVID-19 antibody test

29 March 2021 · Listed under COVID-19, Inflammation across Tissues

An international research team led by Oxford University scientists has developed a portable test for antibodies that fight the novel coronavirus that causes COVID-19. The test, which spots the presence of virus-fighting antibodies rather than a coronavirus infection, can be adapted to work on ... READ MORE

New study finds strong immune response following COVID-19 vaccination

26 March 2021 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics

A new study has found that 99% of people generate a robust immune response against COVID-19 after just one dose of the Pfizer vaccine, and that after two doses levels of protection were even stronger. The PITCH (Protective Immunity from T cells to COVID-19 in Health workers) study, led by ... READ MORE

Oxford academics named NIHR Senior Investigators

3 March 2021 · Listed under Digital Health from Hospital to Home, Inflammation across Tissues, Life-saving Vaccines, Musculoskeletal, Other News, Surgical Innovation, Technology and Evaluation

Four academics supported by the NIHR Oxford Biomedical Research Centre have been awarded a prestigious national award. The University of Oxford  professors have been named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and ... READ MORE

Oxford collaborates with Janssen to map the cellular landscape of immune mediated disorders

16 February 2021 · Listed under Inflammation across Tissues

The University of Oxford has entered into a strategic collaboration with Janssen Biotech to develop a cellular map of genes and proteins implicated across a range of immune-mediated inflammatory disorders and to characterise pharmacologically relevant therapeutic targets. Lead Oxford ... READ MORE

Paper urges use of genomics in care of monogenic IBD

5 January 2021 · Listed under Inflammation across Tissues

Gastroenterology experts have had a position paper published that calls for genomic technologies to be considered an integral part of patient care to investigate patients at risk for monogenic forms of inflammatory bowel disease (IBD). The authors include a number of NIHR Oxford BRC-supported ... READ MORE

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