Academic GPs Dr Clare Taylor and Dr Nick Jones (pictured right) from the University of Oxford’s Nuffield Department of Primary Care Health Sciences outline the findings of the OxVALVE-Survive study and implications for their own clinical practice. Valvular heart disease occurs when valves become either narrowed (stenosis) or leaky (regurgitation). An echocardiogram, or ‘echo’, is … Read more
OUH children’s diabetes service featured on One Show
An innovative new treatment for children with type 1 diabetes that is offered at the Oxford Children’s Hospital has been featured on primetime BBC television. The report shown on The One Show featured six-year-old patient Maebh, who has been fitted with a hybrid closed-loop system, also known as an artificial pancreas, which continually monitors blood … Read more
Blood pressure drugs could protect against type 2 diabetes
Lowering high blood pressure is an effective way to reduce a person’s risk of developing type 2 diabetes in the future, according to a new study. Doctors already prescribe blood pressure-lowering drugs to reduce a person’s chance of having a life-threatening heart attack or stroke, but whether these drugs can help to stave off diabetes … Read more
Whole genome sequencing improves diagnosis of rare diseases, study says
A world-first scientific study has shown that whole genome sequencing (WGS) can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS. The pilot study of rare undiagnosed diseases, published today in the New England Journal of Medicine, involved analysing the genes … Read more
Genetic study highlights links between IBS and mental health disorders
Research funded and supported by the NIHR has revealed that symptoms of irritable bowel syndrome (IBS) may be caused by the same biological processes as mental health conditions such as anxiety. IBS is a common condition worldwide, affecting around 1 in 10 people. The condition causes a wide range of symptoms including abdominal pain, bloating … Read more
Study uncovers gene that doubles risk of death from COVID-19
University of Oxford researchers have identified the gene responsible for doubling the risk of respiratory failure from COVID-19. Sixty percent of people with South Asian ancestry carry the high-risk genetic signal, which could partly explain the excess deaths seen in some UK communities, and the impact of COVID-19 in South Asia. Previous work had already identified … Read more
New PPIE Strategy launched by Oxford BRC
The NIHR Oxford Biomedical Research Centre’s (Oxford BRC) patient and public involvement and engagement (PPIE) strategy 2022-2027 is now finalised and can be viewed from our PPIE Strategy page. The strategy aims to deliver excellent PPIE in collaboration with researchers and PPIE contributors. Excellent PPIE improves research and drives all aspects of involvement in research, … Read more
New therapeutic targets identified to treat inflammatory bowel disease
A new study by University of Oxford researchers has identified potential new therapeutic targets for the treatment of inflammatory bowel disease (IBD), giving hope to millions of patients with ulcerative colitis or Crohn’s disease. The research team from the University’s Kennedy Institute of Rheumatology and Translational Gastroenterology Unit (TGU) were supported by the NIHR Oxford … Read more
QCOVID study identifies vaccinated groups at highest risk hospitalisation and death
Researchers from the University of Oxford have identified which vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death, from 14 days after the second dose of vaccination, when substantial immunity should be expected. The research used the QCovid tool, developed in 2020 with support from the NIHR Oxford Biomedical Research … Read more
Prof Trish Greenhalgh named member of US National Academy of Medicine
Professor Trish Greenhalgh, the NIHR Oxford BRC’s Theme Lead for Partnerships for Health, Wealth and Innovation has been named a member of the US National Academy of Medicine (NAM). Election to the Academy is considered one of the highest honours in the field of health and medicine and recognises individuals who have demonstrated outstanding professional … Read more
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