During the emergency procedure used to reopen the blocked artery that has caused a heart attack, smaller ‘micro’ blood vessels can remain constricted, causing significant damage, according to a new study. The research by Associate Professor Neil Herring of the University of Oxford’s Department of Physiology, Anatomy and Genetics established a key cause of this … Read more
Study discovers genetic changes linked to leukaemia in children with Down’s syndrome
Researchers at the University of Oxford have discovered the specific gene mutations that are required for the development of leukaemia in children with Down’s syndrome. Children with Down’s syndrome have a 150-fold increased risk of myeloid leukaemia, and while some of the genetic causes of this have been previously established, this is the first study … Read more
Research suggests high blood pressure is major cause of heart valve disease
New research has conclusively found that long-term exposure to high blood pressure increases the risk of heart valve disease, with significant implications for clinical practice guidelines and health management. “Clinical practice guidelines currently make little reference to preventative strategies for major valvular heart diseases, but this study highlights that high blood pressure should be considered … Read more
Oxford Blood Group: Exchange Newsletter Issue 3 vol 1 / June 2019
Doctors should offer structured weight loss programmes as treatment for non-alcoholic fatty liver disease
Doctors should offer structured weight loss programmes to patients with non-alcoholic fatty liver disease (NAFLD), new research led by the University of Oxford has found. The study, published in JAMA Internal Medicine, found that weight loss programmes improved measures of liver disease in people with NAFLD, compared with simpler advice. About a quarter of adults … Read more
Oxford patients take part in study to understand role of stress in managing Crohn’s disease
Around 60 Oxford University Hospitals (OUH) NHS Foundation Trust patients are to take part in a study to look at how wearable and mobile devices can help us to understand the relationship between stress and the symptoms of Crohn’s disease, and help to improve management of the condition. The research is part of a larger … Read more
Clinical data project leads to potential advance in understanding of chronic hepatitis B
Researchers and clinicians in Oxford have provided fresh insights into how some people with chronic hepatitis B (CHB) can be cleared of the disease, as part of a national initiative to better use NHS patient data to tackle emerging health issues. It is hoped that the research, the first study on CHB under the auspices … Read more
Online shopping interventions may help customers buy healthier foods
Altering the default order in which foods are shown on screen, or offering substitutes lower in saturated fat could help customers make healthier choices when shopping for food online, according to a study supported by the NIHR Oxford Biomedical Research Centre. The authors, from the University of Oxford’s Nuffield Department of Primary Care Health Sciences, … Read more
Government investment in health research benefits wider economy, study finds
A study has found that government investment in healthcare research is good for the wider economy. The research, supported by the NIHR Oxford Biomedical Research Centre (BRC), found that the return on investment in the Oxford BRC was 46% in terms of income and job creation alone. The paper, ‘A macroeconomic assessment of the impact … Read more
Oxford’s world-class research showcased at BRC Open Day
The breadth of world-class medical research that takes place in Oxford was on show on Friday as the Oxford Biomedical Research Centre hosted an Open Day. Around 400 people attended the event at the John Radcliffe Hospital, which included an exhibition showcasing medical innovations from a wide range of medical fields. A series of public … Read more
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