Volunteers in Oxfordshire are taking part in a new study that will trial a revolutionary new blood test that can detect more than 50 types of cancer before symptoms appear. The aim of the SYMPLIFY study, which is being led by the University of Oxford and is open at Oxford University Hospitals (OUH), is to … Read more
MAIT Cell activation may play role in COVID-19 deaths, study finds
Oxford researchers have found a correlation between deaths from COVID-19 infections and a poorly coordinated systemic immune response, as well as increased activity by Mucosal Associated Invariant T cells, or ‘MAIT cells’. A study involving Oxford BRC-supported researchers published in PLOS Pathogens suggests there is a link between inflammatory responses in the body and increased mortality. In … Read more
Researchers develop algorithm to diagnose deep vein thrombosis
Researchers are developing an artificial intelligence (AI) algorithm to diagnose deep vein thrombosis (DVT) more quickly and as effectively as traditional radiologist-interpreted diagnostic scans, potentially cutting down long patient waiting lists and avoiding patients unnecessarily receiving drugs to treat DVT when they don’t have it. The study, published in the journal Digital Medicine, is the … Read more
Next generation of healthcare leaders showcase projects
The second edition of the NIHR Oxford BRC’s Next Generation Leaders Programme came to a successful close on 6 September with course participants presenting the healthcare research quality improvement projects that had been working on. The Next Generation Leaders Programme has been commissioned and designed by the Oxford BRC to enable early to mid-career researchers … Read more
British Heart Foundation Cardiovascular Catalyst Awards
The BHF are pleased to announce an upcoming call for applications to fund research into the use of advanced analytics to improve cardiovascular care delivery and outcomes in the NHS. A £1 million fund is available, and proposals for research projects lasting up to two years and costing up to £200,000 are invited. Proposals should … Read more
Study investigates responses to COVID-19 treatment in chronic lymphoid leukaemia patients
The COVID-19 pandemic has led to understandable anxiety within the blood cancer community about how their illness may affect their ability to overcome COVID-19 infection. Members of the Oxford Centre for Haematology have led a collaborative research project looking at the response of patients with chronic lymphocytic leukaemia (CLL) who were infected with COVID-19. The … Read more
Lowering blood pressure still beneficial for the heart in old age
Oxford University researchers have found that blood pressure medication is still effective at reducing the risk of a heart attack and stroke in old age, even if blood pressure is in an apparently healthy range. The research by Professor Kazem Rahimi, who is supported by the NIHR Oxford Biomedical Research Centre and the British Heart … Read more
New study launched to understand vaccine escape
Oxford researchers will be involved in a major new study seeking to understand why some people become infected after vaccination or prior infection while others do not Oxford BRC-supported investigators already involved in the Protective Immunity from T-Cells in Healthcare workers (PITCH) study will be part of a consortium of academic partners involved in the … Read more
Vaccination still best protection, but less effective against Delta variant, study finds
The latest findings of an ongoing national study of COVID-19 immunity in households across the UK has found that the Pfizer-BioNTech and Oxford-AstraZeneca vaccines offer good protection against new infections of the Delta variant of concern, but that effectiveness is reduced compared with the Alpha variant. The COVID-19 infection survey, led by Oxford University and … Read more
Second study confirms benefits of budesonide in early stages of COVID-19
A UK-wide clinical study has confirmed the findings of an earlier Oxford BRC-supported study showing that the early treatment with the inhaled asthma medication budesonide speeds up recovery from COVID-19 and reduces the risk of hospitalisation and death. The latest study – part of the PRINCIPLE trial, which is looking at potential treatments for COVID-19 … Read more
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