Scientists at the University of Oxford, have identified how rare populations of abnormal cells drive the formation and persistence of fistulas – painful, tunnel-like tracts that develop in around 30% of people with Crohn’s disease. Crohn’s disease is a long-term disease that affects around one ... READ MORE
News Archive
Oxford-led study shows vaccine protection against Paratyphoid
Results from a newly published study show that a vaccine can protect people against Salmonella Paratyphi A infection. The Oxford-led study demonstrated that an oral live-attenuated vaccine, CVD 1902, provided significant protection against S. Paratyphi A infection in healthy ... READ MORE
Almost 70% of bowel cancers missed at colonoscopy are avoidable
A major nationwide study has revealed that the majority of bowel cancers diagnosed late, after a false-negative colonoscopy could have been prevented or detected earlier. The study, published in Endoscopy, was supported by the National Institute for Health and Care Research (NIHR) Oxford ... READ MORE
World’s largest hip fracture research platform launched to improve care and outcomes
Taking an innovative approach to clinical research in hip fracture, the World Hip Trauma Evaluation (WHiTE) Platform Trial has been launched to test multiple new treatments for patients with fractures of the hip. Hip fractures are a major global health challenge, with 1.3 million cases per year ... READ MORE
Oxford team develops new national course for all UK surgical trainees
A new national online surgical research course designed to equip every surgical trainee in the UK with the skills to critically engage with, and contribute to, surgical research has been developed in Oxford. The National Online Teaching Programme (NOTP) Surgical Research Course provides core ... READ MORE
Underweight children cost NHS as much per child as those with obesity, study finds
The NHS incurs an estimated £340 million in additional healthcare costs annually due to weight-related health problems in children – but it is not just obesity driving the costs. New research from the University of Oxford reveals that underweight children need comparable medical support as ... READ MORE
Towards inclusive sleep science
An Oxford academic paper that suggests current sleep scoring criteria may lead to biased results between sexes and across age groups has been brought back into the spotlight with a recent editorial and podcast. A recent editorial by Prof Monika Haack of Harvard Medical School, published in the ... READ MORE
Oxford researchers pioneer new breathing test to detect lung disease earlier
A new project led by the University of Oxford aims to develop a novel breathing test that could detect asthma and COPD earlier, more accurately, and closer to home, reducing pressure on the NHS and improving outcomes for patients. This work is included in a portfolio of research funded by the ... READ MORE
Two world firsts in myeloma trials at OUH
Two world firsts have taken place in trials at Oxford University Hospitals to tackle the blood cancer myeloma. One of the trials is testing a new tracer to be used on myeloma patients during PET-CT scans; the other is investigating a new potential drug combination therapy. A key factor in both ... READ MORE
Levelling the medical devices playing field for all pregnant women
How can bias in the medical devices used during pregnancy and the neonatal period affect health outcomes, especially for minority ethnic and socio-economically disadvantaged groups? An Oxford University project, supported by the NIHR Oxford Biomedical Research Centre (BRC), is aiming to use the ... READ MORE
Twelve OUH staff embark on their research journey
Twelve members of the Oxford University Hospitals staff from a range of disciplines have begun their research journey by starting two schemes aimed at nurses, midwives, allied health professionals, healthcare scientists, pharmacists and clinical psychologists (NMAHPPS). Six people started the ... READ MORE
Trial shows that suture repair fails to improve digital nerve injury outcomes
The first ever trial of microsurgical suture repair versus nerve alignment for digital nerve injuries suggests suture repair does not improve outcomes. Digital nerve injuries are the most common type of nerve injury treated surgically in the UK, often caused by sharp cuts to the ... READ MORE
Study evaluates effectiveness of cancer diagnosis pathway
A major UK study has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These NSS can indicate a wide range of conditions, from benign diseases to late-stage ... READ MORE
National registry launched to transform care for people at risk of type 1 diabetes
A first-of-its-kind UK registry for children and adults who are at risk of type 1 diabetes has been launched at the University of Oxford. With more than £600,000 of funding from Diabetes UK, the UK Islet Autoantibody Registry aims to transform how people in the earliest stages of type 1 ... READ MORE
Weight loss alone does not ease atrial fibrillation symptoms, study finds
A clinical trial has found that while a structured weight-loss programme helped older adults with atrial fibrillation (AF) shed weight safely and sustainably, it did not improve their heart rhythm symptoms or reduce the need for further treatment. The findings of the LOSE-AF study, which was ... READ MORE
Home-based heart rhythm screening improves diagnosis of common heart condition
A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study led by researchers at Oxford Population Health. The results of the Active Monitoring for Atrial Fibrillation (AMALFI) trial are published in JAMA (The Journal of the American Medical ... READ MORE
OrganOx in record acquisition for Oxford spin-out
An agreement has been reached for the acquisition of OrganOx, a University of Oxford spin-out company transforming kidney and liver transplantation, by the Japanese medical technology company Terumo Corporation for US$1.5 billion. The transaction, which is subject to regulatory and other ... READ MORE
Oxford researchers create first atlas showing cell interaction in lung fibrosis
Researchers have developed the first mathematically supported cellular map of lung tissue in idiopathic pulmonary fibrosis (IPF) and uncovered key immune cell interactions that could explain why lungs fail to repair in this deadly disease with no known cure. The study by researchers at the ... READ MORE
Elevating voices and dispelling distrust
Corina Cheeks has two important roles with the NIHR Oxford Biomedical Research Centre: she is a member of the Diversity in Research Group, a patient and public involvement and engagement (PPIE) group that aims to make involvement in health research more engaging to diverse communities; and she is ... READ MORE
Recruitment opens for UK-wide liver cancer imaging study
A new UK-wide clinical study aimed at transforming liver cancer surveillance in people with cirrhosis has opened to recruitment. The AMULET study, led by the University of Oxford, is comparing a new MRI technique to standard ultrasound surveillance, with a view to improving early detection of ... READ MORE
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