News for Life-saving Vaccines

The University of Oxford has begun a new clinical trial that aims to test tuberculosis (TB) vaccine safety and the host immune response in a first-in-man aerosol mycobacterial challenge infection model. The TB045 trial is being conducted with healthy adult volunteers in partnership with ... READ MORE

Parents are being urged to get their children vaccinated as part of a campaign to boost uptake in the UK amid rising cases of whooping cough and measles. Researchers at the Oxford Vaccine Group, which is part of the University of Oxford and supported by the NIHR Oxford Biomedical Research Centre ... READ MORE

A proposed groundbreaking study that will see participants infected with hepatitis C - and treated - has secured more than £1million in funding. The study will help pave the way for future testing of hepatitis C vaccine candidates. The £1,098,103 funding from the research and grant-making ... READ MORE

A first-of-its-kind study led by the University of Oxford has successfully investigated human immunity against COVID-19 in people who already have antibodies against it. The results suggest that previous infection, together with vaccination, offers strong protection against the original ... READ MORE

University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body. The clinical trial, which used the BCG vaccine delivered via aerosol into participants’ lungs, is a first ... READ MORE

The first participants have received doses of a new vaccine against Nipah virus in a clinical trial by University of Oxford researchers. Nipah virus is a devastating disease mostly found in South-East Asia that can be fatal in up to 75 percent of cases. This first-in-human trial of the vaccine ... READ MORE

The Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded £7.8 million by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential. The awards will fund research into ... READ MORE

Researchers from Oxford and Ghana have shown that small cash incentives increased COVID-19 vaccine uptake in rural Ghana. The findings, published in Nature Medicine, could offer a new strategy for enhancing health interventions in Africa. The recent COVID-19 pandemic highlighted the ... READ MORE

The R21/Matrix-MTM malaria vaccine developed by the University of Oxford and the Serum Institute of India has been recommended for use by the World Health Organisation (WHO), paving the way for its global roll-out. The WHO made the announcement after the vaccine, developed with support from the ... READ MORE

Updated data from the ongoing OCTAVE study reveal, for the first time, the real-world vaccine responses and infection outcomes in clinically at-risk patients with a range of immunocompromised or immunosuppressed conditions. Preliminary data from the landmark OCTAVE study in August 2021 showed ... READ MORE

Researchers from the University of Oxford and their partners have reported new findings from their Phase 2b trial which tested the effectiveness of a booster dose of their candidate malaria vaccine. The vaccine, R21/Matrix-M, had previously demonstrated high-level efficacy of 77 ... READ MORE

University of Oxford researchers have begun recruiting for a phase I clinical trial of a tuberculosis vaccine in human volunteers to develop a new way to test the efficacy of future TB vaccines. The study is led by the Director of the NIHR Oxford Biomedical Research Centre (BRC), Helen McShane, ... READ MORE