Oxford University doctors and scientists are performing the second phase of clinical studies of an experimental Ebola vaccine regimen, with part of the study supported by the NIHR Oxford Biomedical Research Centre. The study is part of the EBOVAC2 project, a collaborative programme involving the University of Oxford, French Institute of Health and Medical Research … Read more
News for Vaccines and Endemic Diseases
BRC supports Oxford Ebola summit
The NIHR Oxford Biomedical Research Centre is among organisations supporting a conference in the city next month about the global response to Ebola. Researchers, Government leaders and industry professionals who led the worldwide fight against Ebola are to come together in Oxford for the first time since the disease was largely controlled. Speakers, including the … Read more
World-first TB vaccination trials enter next stage
THE first ever trials of an aerosol vaccination for tuberculosis in Oxford have shown promising results and volunteers are now being sought for further studies. University of Oxford researchers working at the Churchill Hospital found superior immune responses in the lungs from the trial of a vaccine given via an aerosol which creates a mist … Read more
Scientists showcase search for a meningitis vaccine
THE FIGHT to tackle meningitis was highlighted at a Vaccines and Deadly Diseases Day. The all-day event for young people on Friday at Oxford University Museum of Natural History was part of this year’s Oxfordshire Science Festival. Among those taking part were Oxford University scientists who are trying to find a new meningitis vaccine. Click … Read more
Oxford leads search for longer lasting flu vaccine
Oxford leads search for longer lasting flu vaccine Researchers at Oxford University are leading the search for better flu vaccines. Thousands of people in Oxfordshire have already had the jab to protect them against this year’s strain of flu – but they will need to do it again next year to stay protected. A team … Read more
How has the pneumococcus bacteria evolved after the introduction of a childhood vaccine?
Researchers from the University of Oxford and the US Centers for Disease Control and Prevention (CDC) used the latest DNA sequencing techniques to investigate how pneumococcus bacteria evolved after the introduction of a childhood vaccine in 2000 in the USA. Streptococcus pneumoniae infections are thought to kill around one million young children each year. Although … Read more
First trial of a new hepatitis C vaccine shows promise
A new vaccine against the chronic liver disease hepatitis C has shown promising results in a first clinical trial in humans, Oxford University researchers report. The vaccine, based on a modified cold virus, generated immune responses similar to those seen in the minority of people who are naturally able to clear any infection with the … Read more
Final child vaccinated in clinical trial of new TB vaccine
The vaccination of the final child marks a significant milestone in the development of the MVA85A/AERAS-485 vaccine candidate, the most advanced of any of the new generation of preventative TB vaccines currently being investigated. Tuberculosis kills 1.8 million people per year, and more than 2 billion people worldwide are infected with TB – approximately one … Read more
Universal flu vaccine developed in Oxford
Scientists at Oxford University have successfully tested a universal flu vaccine that could work against all known strains of the illness, taking a significant step in the fight against a disease that affects billions of people each year. The treatment – using a new technique and tested for the first time on humans infected with … Read more
Swine flu clinical trial results published
Last autumn the Oxford Vaccine Group was the lead site on a novel influenza H1N1 (‘Swine Flu’) vaccine study that enrolled over 900 children in 5 weeks. This rapid recruitment enabled us to provide data to the Department of Health in time to directly inform the national ‘Swine Flu’ immunisation policy, and was only possible … Read more