Led by Professor John Frater and Professor Susanna Dunachie
The adult populations most at risk of dying or getting seriously ill from infection are the elderly, people with underlying chronic diseases and those treated with therapies that affect their immune system who do not respond well to vaccines.
Our work focuses on investigating the variations in people’s immune systems that mean they may have a reduced response to vaccination, and trying to identify solutions.
We are also testing different approaches to prevent and treat persistent viral infections such as HIV and hepatitis B and C, which continue to demand resources in the NHS.
We will work with local patient groups, the British Society of Immunology’s patient and public involvement immunosuppression panel, and the NIHR CHERUB collaboration’s extensive work with people living with HIV.