Latest videos (all categories)
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How can sleep improve Parkinson's Care? – Professor Michele Hu
Long before symptoms appear, the body can give us clues if someone will develop Parkinson’s disease.
In this talk, Professor Michele Hu, Consultant Neurologist and Professor of Clinical Neurosciences at the University of Oxford, explains how research has shown that people with REM sleep behaviour disorder often go on to develop Parkinson’s more than a decade later.
The talk was held on 30 January 2024 at Rewley House in Oxford.
By identifying the warning signs early – and potentially treating them – can we intervene to offer Parkinson’s patients and their families a better quality of life?
We believe the involvement of patients and members of the public in research is vital, so if you’re interested in getting involved, please don’t hesitate to reach out to us at OBRCenquiries@ouh.nhs.uk.
To participate in RBD research, please email Professor Michele Hu’s team (Oxford Parkinson’s Disease Centre) at Parkinsons.discovery@nhs.net.
Understanding inflammation – A patient-centred perspective
Gut, skin, joints, brain – inflammation can affect various parts of the body. But for too long we have treated them separately. Now, NIHR Oxford Biomedical Research Centre (BRC) researchers are looking at treatments that recognise the common features across different inflammatory diseases.
In this Oxford BRC public talk, Professor Chris Buckley, Director of Clinical Research at the University of Oxford’s Kennedy Institute of Rheumatology, and patient representative Georgina McMasters, discussed how traditional speciality-driven approaches are evolving into a more holistic, cross-disease perspective.
The talk took place on Tuesday 21 November 2023 at Rewley House, Wellington Square, Oxford.
Impact and benefits of public and community involvement and engagement in health research
Involving patients and members of the public in health research helps to ensure the research benefits those who most need it. This film is an edited version of an in-person session held in September 2023 where researchers from Oxford Biomedical Research Centre, University of Oxford and patient and public contributors described the benefits of involving patients and members of the public in research.
In this session we discussed:
00:00 -Talks Trialblazers: a project putting patients in the driving seat of clinical trials.
13:11 – Diversity in Research a participatory case study to understand and optimise the impact of a diverse public involvement group in biomedical research.
28:01 – What is public and community engagement in the context of global health research? Overview and examples from OUCRU in Vietnam [lhttps://www.oucru.org/], KEMRI-Wellcome in Kenya [https://kemri-wellcome.org/] and Oxford Health Systems Collaborative [https://www.cghr.ox.ac.uk/research/health-systems-collaborative].
41:15 – Why and how to evaluate public and community engagement, with examples of a range of evaluation practice and evidence.
Thanks for watching!
Can we really replace the hospital? – Prof. Dan Lasserson
Professor Dan Lasserson was one of the first doctors in the country to provide hospital care at home using a range of point of care diagnostic technology, which allows clinicians to look after people with more complex acute illness who previously would be taken straight to hospital.
Here, in an NIHR Oxford Biomedical Research Centre (BRC) public talk at the Said Business School on 11 October 2023, Professor Lasserson explains how digital innovations can be deployed for acute medical care in the home and care home and asking: 'Can we really replace the hospital?'
Professor Lasserson is Clinical Lead, Acute Hospital at Home Service, Oxford University Hospitals NHS Foundation Trust; Professor of Acute Ambulatory Care, University of Warwick; and sub-theme lead within the Digital Health from Hospital at Home Theme of the Oxford BRC.
His OUH Hospital at Home team is featured in this BBC Panorama programme on the future of the NHS.
https://www.bbc.co.uk/iplayer/episode/m001h917/panorama-the-nhs-crisis-can-it-be-fixed
NIHR Oxford BRC public talk: How will using blood tests to detect cancer change the NHS?
There is growing interest in the possibility of using blood tests to detect cancer. If such tests become available, they could transform how we diagnose and look after people with the disease.
This offers exciting possibilities, but also many potential pitfalls. Blood tests could be used to screen apparently healthy people for cancer, to decide who should have more tests, or even replace scanning as a means of monitoring the effects of treatment or whether cancer has come back.
In this talk, Professor Mark Middleton, Director of the Cancer Research UK Oxford Centre, explains how we are developing these tests and assessing their use in clinical trials.
Sue Duncombe, a member of the Oxford Patient and Public Involvement (PPI) Group, talks about this development in early cancer detection from a patient perspective.
The talk was held on Tuesday 29 November 2022.
Richard Bulbulia presents Surgery or stents – which is more effective in preventing stroke?
Stroke is the second largest cause of death worldwide, responsible for over six million deaths each year. A common cause of stroke is carotid artery disease, which can be treated in one of two ways: carotid artery surgery; or having a stent fitted, with a view to improving blood flow to the brain. Until recently, it has been unclear which of these procedures results in better overall patient outcomes.
To answer this question, researchers at Oxford Population Health at the University of Oxford have coordinated the Asymptomatic Carotid Surgery Trial 2 (ACST-2), the largest trial to date comparing the outcomes of the 2 procedures.
In this talk, research fellow and consultant vascular surgeon Richard Bulbulia will discuss the findings of the ACST-2 trial and whether patient factors favour one approach over another when treating those at risk of a stroke.
Luke Jostins discusses- Measuring the relationship between anxiety, irritable bowel syndrome
In this talk, Luke Jostins Dean, associate professor and Sir Henry Dale fellow at the Kennedy Institute of Rheumatology, talks about his research into the relationship between anxiety and irritable bowel syndrome, and whether there is a genetic link.
Luke discusses the outcome of a large survey about digestive and mental health, completed by over 170 thousand volunteers, and what it has told us about the relationship between IBS, mental health and genetics.
Prof Kazem Rahimi discussed Blood pressure and Diabetes
Kazem Rahimi, Professor of Cardiovascular Medicine and Population Health, gave an online public talk about his research into whether lowering blood pressure can help to prevent type 2 diabetes, and the extent to which a person’s blood pressure or their treatment affects their risk of developing diabetes.
Ideas and tips for involving people from diverse communities in research
Patients and members of the public from the Oxford and Oxford Health BRCs’ Diversity in Research Group provide advice and insights to researchers about working with people from diverse communities. This event in March 2022 was attended by 60 researchers and members of the public.
How researchers improve their research through involving diverse communities
When we involve patients, carers and other members of the public in our research – including them in the design and delivery of our clinical trials and studies – it improves it and ensures it benefits the people and communities who need it most.
It is even more important that the voices of people from diverse and under-served communities are heard when we are designing our studies.
In this video, researchers explain how involving patients and members of the public from different communities has added value to their research and made it more effective.
Involving people from diverse communities in healthcare research
When we involve patients, carers and other members of the public in our research – including them in the design and delivery of our clinical trials and studies – it improves it and ensures it benefits the people and communities who need it most.
It is even more important that the voices of people from diverse and under-served communities are heard when we are designing our studies.
In this video, patient and public involvement and engagement contributors explain the value they have brought to research studies.
Poor outcomes after delirium during acute hospital admission. Dr Jasmine Gan, Oxford 2021
Poor outcomes in delirium: finds from an observational cohort of over 1,700 unselected acute medicine patients
Patient & Public Involvement webinar: A philosopher’s approach to equality
A commitment to provide equal opportunities for all and address any barriers to diverse and inclusive patient and public involvement (PPI) in research seems a non-disputable moral good. But why is unequal access to PPI morally problematic? Is the absence of marginalised or seldom heard groups always wrong? What are the ethical standards that a health researcher should follow when designing, implementing and assessing their PPI strategies?
This webinar was presented by Dr Sapfo Lignou.
Crohn's Disease and Ulcerative Colitis – Public Information Event
On 29 April 2021 leading clinicians and scientists from the Oxford Translational Gastroenterology Unit will present on the latest research into the causes, treatment and monitoring of Crohn’s and Colitis.
NIHR Oxford BRC patient and public involvement and engagement
In line with its aim to have the public and patients at the core of its research, the NIHR Oxford Biomedical Research Centre (BRC) has been working with a group which includes teenagers, young adults, carers and people from black, Asian and minority ethnic communities.
The project is part of the development of a new strategy and had a particular focus on making health research accessible. Group members had a range of experience of health services; including learning disabilities, autism, cancer and mental health services. They were supported by BRC staff and long-standing contributors.
The group reviewed materials such as advertisements and handbooks, researcher talks and webinars. They explored the BRC’s website, giving insight into what worked well and where improvements could be made. They made useful recommendations on issues such as: accessibility for a range of audiences and how and where patients and public feature in content.
If you would like to get involved in the BRC’s research, or to learn more about it, please email: GetInvolved@ouh.nhs.uk
What lymphoma research is happening in Oxford?
This production outlines the lymphoma research currently being undertaken in Oxford. We hear from both patient and clinician participants in clinical trials.
The production covers:
1. The importance of taking part in research for both patients and clinicians
2. The scope of research
3. Collaboration and teamwork in research
4. The advantages of being part of a clinical trial
If you would like further information please check out the following links:
Oxford BRC Haematology:
https://oxfordbrc.nihr.ac.uk/research-themes-overview/haematology-and-stem-cells/
NIHR
https://www.nihr.ac.uk
Oxford lymphoid disorders study group
https://www.cancercentre.ox.ac.uk/research/consortia/oxford-lymphoid-disorders-study-group/
EPCTU
https://www.oncology.ox.ac.uk/research/srf/early-phase-clinical-trials-unit
Oxford Centre for Haematology
https://www.rdm.ox.ac.uk/about/our-clinical-facilities-and-mrc-units/och
Clinical academic career pathways for nurses, midwives and allied health professionals
In this event on 22 March 2021, a panel of clinical academic researchers discussed their experiences in research, the benefits of clinical academic roles and how we can improve support for these career pathways.
Speakers:
Chair: Dr Helen Walthall, Director of Nursing and Midwifery Research and Innovation at Oxford University Hospitals NHS Foundation Trust and NMAHP Education and Training Lead for the Oxford Biomedical Research Centre
Dr Cathy Henshall, NIHR CRN Associate Director of Nursing (70@70), Reader at Oxford Brookes University and Head of Research Delivery at Oxford Health NHS Foundation Trust
Kay Mitchell, NIHR 70@70 Senior Nurse Research Leader, Academic Career Development Lead at NIHR Southampton Biomedical Research Centre and Associate Director at Southampton Academy of Research
Dr Louise Strickland, Clinical Academic Nurse Researcher, Trainee Surgical Care Practitioner, Department of Spinal Surgery, Oxford University Hospitals NHS Foundation Trust.
Patient and public involvement webinar: Statistics
Jacqueline Birks, Senior Medical Statistician, presented this webinar on 19 March 2021, which provides an introduction to statistics in health and medical research with examples from COVID-19 studies.
Parliament Science and Technology Committee – PHOSP Consortium & NIHR-BHF Cardiovascular Partnership
Parliament Science and Technology committee session: 15 September 2020
Subject: The science of COVID-19
Discussion: How research from the PHOSP Consortium and the NIHR-BHF Cardiovascular Partnership will help better understand Covid-19 susceptibility, risk factors and sequelae
Speakers include Sonya Babu-Narayan (BHF Associate Medical Director), Kamlesh Khunti (Prof. at the University of Leicester and member of the PHOSP Cardiovascular Working Group that the Partnership leads) and Prof. Chris Brightling (Chief Investigator of the PHOSP Consortium)
Can asthma inhalers prevent COVID-19 hospitalisations? The STOIC Study – Prof Mona Bafadhel
In this talk from 16 March 2021, Prof Mona Bafadhel discusses her recent research on the use of inhaled corticosteroids (usually used for asthma and COPD) to reduce the chances of severe respiratory illness in COVID-19 patients.
Mona Bafadhel is Associate Professor of Respiratory Medicine at the University of Oxford and a Consultant Respiratory Physician. Her research focuses on chronic obstructive pulmonary disease (COPD), a set of conditions that cause the airways to become inflamed and make it harder for patients to breathe.
In this event, Mona talks about:
– The background to the STOIC study (Steroids in Covid Study)
– Early clinical observations that respiratory disease was an infrequent finding in people hospitalised with COVID-19
– Early laboratory findings that viral replication seemed to be reduced by inhaled corticosteroids
– What we already know about asthma, COPD and viruses
– The STOIC Study design – who was eligible to volunteer
– What happened during the study
– The study outcomes – primary and secondary endpoints
– Data on the study volunteers and their symptoms
– Results of the study – primary and secondary endpoints
– Strengths and limitations of the study
– Q&A
More information:
https://clinicaltrials.gov/ct2/show/NCT04416399
https://www.ndm.ox.ac.uk/team/mona-bafadhel
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