Videos: COVID-19 research

Martin Landray, Professor of Medicine and Epidemiology at the Nuffield Department of Population Health and Oxford BRC Theme Lead for Clinical Informatics and Big Data, discusses research into treatments for COVID-19 and how the RECOVERY trial was rapidly set up to test the effects of potential drug treatments.

Andrew Pollard, Professor of Paediatric Infection and Immunity at the Department of Paediatrics and Oxford BRC Co-Theme Lead for Vaccines speaks about the development of a vaccine candidate for COVID-19 and the progress of its clinical trials.

Julia Hippisley-Cox, Professor of Clinical Epidemiology and General Practice at the Nuffield Department of Primary Care Health Sciences, will discuss her research into risk prediction models for a range of diseases, including COVID-19, and how these tools can be used to improve healthcare and support the NHS.

In this talk from 16 March 2021, Prof Mona Bafadhel discusses her recent research on the use of inhaled corticosteroids (usually used for asthma and COPD) to reduce the chances of severe respiratory illness in COVID-19 patients. Mona Bafadhel is Associate Professor of Respiratory Medicine at the University of Oxford and a Consultant Respiratory Physician. Her research focuses on chronic obstructive pulmonary disease (COPD), a set of conditions that cause the airways to become inflamed and make it harder for patients to breathe. In this event, Mona talks about: – The background to the STOIC study (Steroids in Covid Study) – Early clinical observations that respiratory disease was an infrequent finding in people hospitalised with COVID-19 – Early laboratory findings that viral replication seemed to be reduced by inhaled corticosteroids – What we already know about asthma, COPD and viruses – The STOIC Study design – who was eligible to volunteer – What happened during the study – The study outcomes – primary and secondary endpoints – Data on the study volunteers and their symptoms – Results of the study – primary and secondary endpoints – Strengths and limitations of the study – Q&A More information: https://clinicaltrials.gov/ct2/show/NCT04416399 https://www.ndm.ox.ac.uk/team/mona-bafadhel