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You are here: Home > News listings for COVID-19

News for COVID-19

OUH agrees long COVID research collaboration with Polarean

11 May 2022 · Listed under COVID-19, Imaging, Respiratory

Oxford University Hospitals (OUH) and the medical imaging technology company, Polarean Imaging plc, have entered into a research collaboration to study the long-term effects of COVID-19 in patients who are still experiencing breathlessness months after infection.  Polarean produce an investigational drug‑device combination product using hyperpolarised xenon gas to enhance magnetic resonance imaging (MRI) in pulmonary medicine. … Read more

Study finds no increased risk of rare neurological events after COVID vaccination

17 March 2022 · Listed under COVID-19, Musculoskeletal, Neurological Conditions

A study of more than eight million people has found no increased risk of rare neurological events after COVID -19 vaccination. However, the researchers did find a higher risk of Bell’s palsy (facial weakness), encephalomyelitis (inflammation of the brain and spinal cord) and Guillain-Barré syndrome (a nerve condition) after COVID-19 infection. The study, which was … Read more

Blog: Developing a process to monitor populations at increased risk from coronavirus

11 March 2022 · Listed under Antimicrobial Resistance and Modernising Microbiology, COVID-19

Emma Pritchard is a Medical Statistician in the Modernising Medical Microbiology team at the John Radcliffe Hospital in Oxford. She works in the Oxford BRC’s Antimicrobial Resistance and Modernising Microbiology Theme. In this blog, Emma explains how she used the ongoing Office for National Statistics COVID-19 Infection Survey to understand the spread of coronavirus in … Read more

Brain regions related to smell show decline after mild COVID-19

7 March 2022 · Listed under Clinical Informatics and Big Data, COVID-19, Neurological Conditions

University of Oxford researchers have found tissue damage and greater shrinkage in brain areas related to smell in people following mild SARS-CoV-2 infection. The researchers, who were supported by the NIHR Oxford Biomedical Research Centre (BRC) used data from UK Biobank participants to look at changes to the brain on average four and a half … Read more

RECOVERY trial finds another drug to treat hospitalised COVID-19 patients

3 March 2022 · Listed under Clinical Informatics and Big Data, COVID-19

The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has found another drug that reduces the risk of death in hospitalised patients with the disease. The Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial showed that baricitinib, an anti-inflammatory drug normally used to treat rheumatoid arthritis, reduces the risk of death when given to hospitalised patients with … Read more

NIHR highlights QCOVID role in tackling pandemic

2 March 2022 · Listed under Clinical Informatics and Big Data, COVID-19, Multimorbidity and Long-Term Conditions

The National Institute for Health Research (NIHR) has published a case study on QCOVID, a clinical risk prediction model, which has played a key role during the COVID-19 pandemic in identifying those people at greatest risk. QCOVID, developed with support from the NIHR Oxford Biomedical Research Centre, has proved an important tool to determine which … Read more

Oxford BRC’s ability to deliver rapid COVID-19 research response highlighted

22 February 2022 · Listed under Clinical Informatics and Big Data, COVID-19, Vaccines for Emerging and Endemic Diseases

Oxford Biomedical Research Centre (BRC) researchers have highlighted how the BRC’s infrastructure gave it the agility and capacity to respond rapidly with research projects to tackle COVID-19. In a commentary published in the open access BMC Health Research Policy and Systems journal, the BRC team said the development of the Oxford AstraZeneca (AZ) vaccine and the … Read more

COVID-19 blog: accelerating testing with robotics

21 February 2022 · Listed under Antimicrobial Resistance and Modernising Microbiology, COVID-19

PhD student Kevin Chau, who works in the Oxford BRC’s Antimicrobial Resistance and Modernising Microbiology Theme, has played his part in the pandemic response as part of the Modernising Medical Microbiology team at the John Radcliffe Hospital in Oxford. In this blog post written for the Medical Research Foundation, he describes the experience: The swift … Read more

Review highlights impact of Long COVID on cardiovascular system

18 February 2022 · Listed under Cardiovascular, COVID-19, Imaging

The wide-ranging effects of long COVID and the associated issues for healthcare providers have been revealed in a new review of the major studies into the condition, which specifically highlights the impact of long COVID on the cardiovascular system. The review, published in the European Heart Journal, spans each step from a patient’s original coronavirus … Read more

Lung abnormalities found in long COVID patients with breathlessness

29 January 2022 · Listed under COVID-19, Imaging

Researchers have identified abnormalities in the lungs of long COVID patients who are experiencing breathlessness that cannot be detected with routine tests. The EXPLAIN study, which involves teams in Oxford, Sheffield, Cardiff and Manchester, is using hyperpolarised xenon MRI scans to investigate possible lung damage in long COVID patients who have not been hospitalised with … Read more

Drug could more effectively treat patients hospitalised with COVID-19 pneumonia, research finds

17 December 2021 · Listed under COVID-19, Musculoskeletal

A proof-of-concept trial involving Oxford researchers has identified a drug that may benefit some patients hospitalised with COVID-19 pneumonia. The CATALYST Trial tested the rheumatoid arthritis treatment namilumab as a potential therapeutic to treat patients who are hospitalised with COVID-19 pneumonia and receiving ‘usual’ care, but who also have high levels in their blood of … Read more

People with long COVID after hospitalisation face limited recovery after one year

16 December 2021 · Listed under COVID-19, Imaging, Respiratory

People who were hospitalised with COVID-19 and continued to experience symptoms five months later show limited further recovery one year after hospital discharge, according to the latest results of a major national study looking at the long-term health impacts of COVID-19 on hospitalised patients The latest findings of the PHOSP-COVID study, which involves several researchers … Read more

COVID-19 infection more likely than vaccines to cause rare cardiovascular complications

14 December 2021 · Listed under Clinical Informatics and Big Data, COVID-19, Vaccines for Emerging and Endemic Diseases

Researchers have reported the results of the largest ever study to compare the risks of cardiovascular events – such as myocarditis, pericarditis, and cardiac arrhythmia – between different vaccines and COVID-19 infection, and the first to investigate the association between cardiac events and the Oxford-AstraZeneca vaccine. The study, led by University of Oxford researchers supported … Read more

RECOVERY Trial launched in South Africa

9 December 2021 · Listed under Clinical Informatics and Big Data, COVID-19

The world’s largest clinical trial investigating treatments for COVID-19 has now been launched in South Africa, with the first patient recruited today. Since March 2020, the RECOVERY Trial, which is supported by the NIHR Oxford BRC, has discovered three effective treatments for COVID-19: the inexpensive steroid dexamethasone; the arthritis drug tocilizumab; and a monoclonal antibody … Read more

Study uncovers gene that doubles risk of death from COVID-19

5 November 2021 · Listed under COVID-19, Genomic Medicine

University of Oxford researchers have identified the gene responsible for doubling the risk of respiratory failure from COVID-19. Sixty percent of people with South Asian ancestry carry the high-risk genetic signal, which could partly explain the excess deaths seen in some UK communities, and the impact of COVID-19 in South Asia. Previous work had already identified … Read more

QCOVID study identifies vaccinated groups at highest risk hospitalisation and death

25 October 2021 · Listed under COVID-19, Technology and Digital Health

Researchers from the University of Oxford have identified which vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death, from 14 days after the second dose of vaccination, when substantial immunity should be expected. The research used the QCovid tool, developed in 2020 with support from the NIHR Oxford Biomedical Research … Read more

RECOVERY Trial paper wins BMJ’s Research Paper of the Year Award

1 October 2021 · Listed under Clinical Informatics and Big Data, COVID-19

The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has been announced as the 2021 winner of The British Medical Journal’s prestigious UK Research Paper of the Year Award.  The award recognises original UK research that has the potential to contribute significantly to improving health and healthcare. The paper, “Dexamethasone in Hospitalized Patients … Read more

Moonshot initiative to develop affordable COVID-19 antivirals gets funding boost

27 September 2021 · Listed under COVID-19

The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-19 and future viral pandemics has received key funding of £8 million from the Wellcome Trust, on behalf of the Covid-19 Therapeutics Accelerator. “Faced with global vaccine inequality and the … Read more

MAIT Cell activation may play role in COVID-19 deaths, study finds

17 September 2021 · Listed under COVID-19, Gastroenterology and Mucosal Immunity

Oxford researchers have found a correlation between deaths from COVID-19 infections and a poorly coordinated systemic immune response, as well as increased activity by Mucosal Associated Invariant T cells, or ‘MAIT cells’. A study involving Oxford BRC-supported researchers published in PLOS Pathogens suggests there is a link between inflammatory responses in the body and increased mortality. In … Read more

Study investigates responses to COVID-19 treatment in chronic lymphoid leukaemia patients

27 August 2021 · Listed under COVID-19, Haematology and Stem Cells, Oxford Blood Group

The COVID-19 pandemic has led to understandable anxiety within the blood cancer community about how their illness may affect their ability to overcome COVID-19 infection. Members of the Oxford Centre for Haematology have led a collaborative research project looking at the response of patients with chronic lymphocytic leukaemia (CLL) who were infected with COVID-19. The … Read more

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  • BRC study outlines researchers training needs and barriers 20 May 2022
  • Three new Blood and Transplant Research Units created in Oxford 18 May 2022
  • Oxford’s medical, health and life sciences research excellence recognised 12 May 2022
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