The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has found that a monoclonal antibody combination developed by US company Regeneron reduces deaths for hospitalised COVID-19 patients who have not mounted their own immune response. The ... READ MORE
COVID-19 News
BRC-supported researchers recognised in Queen’s Birthday Honours
A number of NIHR Oxford BRC-supported researchers who have played prominent roles in the global response to the COVID-19 pandemic have been honoured as part of the Queen’s Birthday Honours List. The researchers, who have developed new vaccines or identified new drug treatments, have saved many ... READ MORE
RECOVERY trial finds aspirin does not improve survival for hospitalised COVID-19 patients
The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has found that in patients hospitalised with COVID-19, aspirin is not associated with reductions in mortality or in the risk of progressing to invasive mechanical ventilation or death. In ... READ MORE
AI detects life-threatening blood vessel inflammation from COVID-19 variants
New artificial intelligence (AI) technology to scan for heightened blood vessel inflammation can calculate a person’s risk of death from COVID-19 and COVID-19 variants. The technology could be used to tailor their treatment and give them the best chance of recovery, according to new research ... READ MORE
Study confirms longer-term lung damage after COVID-19
A study by Oxford and Sheffield researchers using a cutting-edge method of imaging has identified persistent damage to the lungs of COVID-19 patients at least three months after they were discharged from hospital, and for some patients even longer. This damage was not detected by routine CT ... READ MORE
Trial finds no benefit from using colchicine in hospitalised COVID-19 patients
The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has found no evidence that that the drug colchicine has any meaningful clinical benefits for patients hospitalised with COVID-19. Colchicine is used to treat inflammation and pain in ... READ MORE
Messaging focused on personal rather than collective benefits more effective for COVID-19 vaccination
The largest ever study of COVID-19 vaccine messaging shows that emphasising the personal benefits of vaccination may be the most effective way to persuade people who are sceptical about the jab. For the one in ten who say they won't take a COVID-19 vaccine, messaging that focuses on personal ... READ MORE
Oxford BRC researchers named among new Academy of Medical Sciences fellows
A number of leading researchers supported by the NIHR Oxford Biomedical Research Centre are among 50 prominent biomedical and health scientists elected to the Academy of Medical Sciences’ respected and influential Fellowship. The new Fellows include Oxford BRC experts who have spearheaded the ... READ MORE
Data reveals COVID-19 risk factors for people with type 1 diabetes
The largest study of people with type 1 diabetes admitted to hospital with COVID-19 has found that those with higher body mass index (BMI), poorer kidney function and the presence of microvascular complications were at greater risk of death and/or admission to intensive care. However, the ... READ MORE
Study highlights role of BMI in increased COVID-19 risks
A study by University of Oxford researchers has found that the risk of admission to hospital, admission to ICU or death from COVID-19 increases progressively above a ‘normal’ BMI of 23, even without other comorbidities. The research team, who are supported by the NIHR Oxford Biomedical Research ... READ MORE
Azithromycin not effective against COVID-19, trial confirms
A clinical trial by University of Oxford researchers has confirmed that the antibiotic azithromycin has no clinical benefit in people with moderate COVID-19. The ATOMIC2 trial, which was supported by the NIHR Oxford Biomedical Research Centre (BRC), was established to investigate if a common ... READ MORE
National survey reveals big reductions in COVID-19 infections with single dose of Oxford-AZ and Pfizer vaccines
Data from the national COVID-19 Infection Survey, which is led by senior NIHR Oxford BRC researcher Professor Sarah Walker, has revealed the impact of vaccination on antibody responses and new infections in a large group of adults from the general population. This major community surveillance ... READ MORE
Human challenge trial launches to study immune response to COVID-19
Researchers at the University of Oxford have launched a human challenge trial to look at what kind of immune response can stop people from becoming re-infected. The team, led by the NIHR Oxford Biomedical Research Centre Director Professor Helen McShane (pictured right), also want to find out ... READ MORE
National study looks at long-term lung damage from COVID-19
A new national study involving researchers from Oxford will investigate the long-term effects of lung inflammation and scarring from COVID-19. The study, launched with £2 million of funding from UK Research and Innovation (UKRI), aims to develop treatment strategies and prevent ... READ MORE
Risk of severe COVID-19 from asthma and other respiratory diseases may be only modestly increased, new analysis suggests
An analysis of 8.3 million health care records in England shows that people with asthma have only a small increased risk of developing severe Covid-19. The study, led by University of Oxford researchers, examined routine patient data collected between January and April 2020 to generate risk ... READ MORE
Oxford researchers release cheap, quick COVID-19 antibody test
An international research team led by Oxford University scientists has developed a portable test for antibodies that fight the novel coronavirus that causes COVID-19. The test, which spots the presence of virus-fighting antibodies rather than a coronavirus infection, can be adapted to work on ... READ MORE
New study finds strong immune response following COVID-19 vaccination
A new study has found that 99% of people generate a robust immune response against COVID-19 after just one dose of the Pfizer vaccine, and that after two doses levels of protection were even stronger. The PITCH (Protective Immunity from T cells to COVID-19 in Health workers) study, led by ... READ MORE
Seven in ten patients hospitalised with COVID-19 not fully recovered five months after discharge
A majority of survivors who left hospital following COVID-19 had not fully recovered five months after discharge and continued to experience negative impacts on their physical and mental health, as well as their ability to work, according to results released by a major national study into the ... READ MORE
Two doses of vaccine offer same protection from COVID as prior infection, study finds
Two doses of either the Pfizer or Oxford-AstraZeneca vaccine offer similar protection against symptomatic SARS-CoV-2 infection to that coming from natural immunity after infection, an ongoing study of healthcare workers has found. None of the 1,456 healthcare workers at Oxford University ... READ MORE
Oxford study reveals public attitudes to vaccine roll-out programmes
An international study led by University of Oxford health economists and political scientists has found that there is much greater consistency in public attitudes across a number of countries about who should be prioritised for COVID-19 vaccination than there is in national policies. The study, ... READ MORE
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