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News for Cardiovascular

Eight BRC projects get RCF funding

· Listed under Cardiovascular, Clinical Informatics and Big Data, Diabetes and Metabolism, Gastroenterology and Mucosal Immunity, Genomic Medicine, Haematology and Stem Cells, Imaging, Molecular Diagnostics, Multi-Modal Cancer Therapies, Multimorbidity and Long-Term Conditions, Neurological Conditions, Stroke and Vascular Dementia, Surgical Innovation and Evaluation, Technology and Digital Health

Eight Oxford BRC proposals, many covering a number of themes, have been awarded NIHR Research Capability Funding (RCF) funding to take forward key areas of research. The selected projects that will be supported include: Developing a research centre devoted to urgent and acute care The creation of a state-of-the-art imaging centre; and of a new … Read more

Common heart medication does not increase risk of COVID-19 hospitalisation

· Listed under Cardiovascular, Clinical Informatics and Big Data, COVID-19, Technology and Digital Health

A study by Oxford researchers, supported by the NIHR Oxford Biomedical Research Centre (BRC), found that ACE inhibitors and ARBs – both common treatments for high blood pressure and heart failure – are not generally linked to an increased risk of severe COVID-19 disease or an increased likelihood of being admitted to intensive care. However, … Read more

Thousands miss out on life-saving heart attack treatment due to COVID-19 pandemic

· Listed under Cardiovascular, Clinical Informatics and Big Data, COVID-19

Researchers at the University of Oxford have published new research that shows that by the end of May there had been about 5,000 fewer hospital admissions with heart attack in 2020 than would be expected, suggesting that many patients have missed out on lifesaving treatment. The research showed that the number of admissions to hospital … Read more

Link between high cholesterol and aortic valve disease risk found

· Listed under Cardiovascular, Multimorbidity and Long-Term Conditions

Oxford researchers have found that while having high cholesterol levels does not influence a person’s risk of aortic or mitral regurgitation, it does increase their risk of developing another major heart valve disease – aortic stenosis. Aortic stenosis is the most common form of heart valve disease in developed countries and is thought to affect … Read more

Oxford haematologists win national awards to further their research

· Listed under Cardiovascular, Haematology and Stem Cells

Two consultant haematologists at the Oxford Haemophilia and Thrombosis Centre (OHTC), based at the Churchill Hospital, have been awarded funding for their research as part of a new national scheme. Dr Nicola Curry and Dr Susie Shapiro were among the recipients of the new Clinical Academic Research Partnerships (CARPs), awarded by the Medical Research Council … Read more

AI identifies ‘fingerprint’ that predicts heart attack risk

· Listed under Cardiovascular

Oxford researchers have developed a new biomarker – derived through artificial intelligence analysis of routine CT scans – that can identify people at high risk of a fatal heart attack at least five years before it strikes. The researchers, who are supported by the NIHR Oxford Biomedical Research Centre, developed the new fat radiomic profile … Read more

Heart failure care must address patients’ broader health if survival rates are to improve

· Listed under Cardiovascular, Clinical Informatics and Big Data, Multimorbidity and Long-Term Conditions

Oxford BRC-supported researchers have provided new evidence that might explain why the prognosis of heart failure patients has improved so little over the past decade. Findings show that a decline in cardiovascular deaths has been offset by an increase in the number of deaths from infections and respiratory problems, highlighting the importance of focusing on … Read more

New approach to reducing damage after a heart attack

· Listed under Cardiovascular, Imaging, Other News

During the emergency procedure used to reopen the blocked artery that has caused a heart attack, smaller ‘micro’ blood vessels can remain constricted, causing significant damage, according to a new study. The research by Associate Professor Neil Herring of the University of Oxford’s Department of Physiology, Anatomy and Genetics established a key cause of this … Read more

Research suggests high blood pressure is major cause of heart valve disease

· Listed under Cardiovascular, Multimorbidity and Long-Term Conditions

New research has conclusively found that long-term exposure to high blood pressure increases the risk of heart valve disease, with significant implications for clinical practice guidelines and health management. “Clinical practice guidelines currently make little reference to preventative strategies for major valvular heart diseases, but this study highlights that high blood pressure should be considered … Read more

Women and older people most likely to experience shortcomings in heart failure care

· Listed under Cardiovascular, Clinical Informatics and Big Data

A study of 93,000 UK adults with heart failure has revealed critical care shortcomings in diagnostic tests, drug prescriptions, and follow-up patterns, with women and those over 75 years of age disproportionately affected. The study by The George Institute for Global Health at the University of Oxford, supported by the Oxford BRC, investigated the medical … Read more

Oxford researchers spot tell-tale signs of potentially fatal cardiac condition

· Listed under Cardiovascular, Imaging

Researchers in Oxford have employed a technique more commonly used in brain imaging to identify the tell-tale signs of the potentially fatal heart condition hypertrophic cardiomyopathy, the leading cause of sudden cardiac death in young people. This Oxford BRC-supported study is the first time these microscopic heart muscle abnormalities have been spotted in living patients. … Read more

Event showcases BRC work tackling chronic diseases

· Listed under Cardiovascular, Diabetes and Metabolism, Multimorbidity and Long-Term Conditions, Neurological Conditions, Obesity, Diet and Lifestyle, Stroke and Vascular Dementia

Around 170 people attended a BRC event on Tuesday (26 March) that provided an opportunity to network and to hear about the breadth of research taking place in Oxford to combat chronic diseases such as diabetes, obesity, cardiovascular disease and dementia. The Chronic Disease Cluster, which brings together six research themes – Obesity, Multimorbidity, Diabetes, … Read more

Only “modest” improvement in heart failure survival rates since 2000

· Listed under Cardiovascular, Multimorbidity and Long-Term Conditions

Survival after a diagnosis of heart failure in the United Kingdom has shown only modest improvement in the 21st Century and lags behind other serious conditions, such as cancer, a large study supported by the Oxford Biomedical Research Centre has found. The findings, published by the BMJ, also show that survival is worse for people … Read more

Nitric Oxide conference gets under way in Oxford

· Listed under Cardiovascular

Delegates from round the world have descended on Oxford for the 10th international conference of the Nitric Oxide Society, which has got under way. This year, the NIHR oxford Biomedical Research Centre is among the sponsors of the event. The conference, which is being held at the University of Oxford’s Mathematical Institute and lasts until … Read more

Study shows new technology can predict fatal heart attacks

· Listed under Cardiovascular, Imaging

Researchers at the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre (BRC), have developed a new technology based on analysis of computed tomography (CT) coronary angiograms that can identify patients at risk of deadly heart attacks years before they occur. Heart attacks are usually caused by inflamed plaques in the coronary artery … Read more

Lifestyle factors linked to brain health of young adults

· Listed under Cardiovascular, Imaging

Researchers at Oxford’s John Radcliffe Hospital have used advanced magnetic resonance imaging (MRI) to investigate whether factors such as blood pressure, fitness, smoking and alcohol intake during young adult life are associated with changes in the blood vessels inside the brain. The University of Oxford researchers, supported by the NIHR Oxford Biomedical Research Centre, collaborated … Read more

Fourth digital health product developed as part of Sensyne agreement

· Listed under Cardiovascular, Technology and Digital Health

A software product that underpins a remote management service for patients with heart failure has been licensed by the UK digital health company Sensyne Health as part of a strategic research agreement with the University of Oxford and Oxford University Hospitals (OUH) NHS Foundation Trust. Support-HF is the fourth digital health product to be commercialised … Read more

Premature hearts less able to cope with exercise

· Listed under Cardiovascular

The hearts of people born prematurely are less able to cope with the pressures of exercise in adulthood, according to a new study funded by the NIHR Oxford Biomedical Research Centre. The findings, published in the Journal of the American College of Cardiology, might explain why people born prematurely are more likely to develop heart … Read more

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