Replacing all regular meals with a low calorie diet of soups, shakes and bars, together with behavioural support, is cost-effective as a routine treatment for obesity, according to researchers from the University of Oxford. Published today in the journal Obesity, the study is the first to estimate the long term health benefit and builds on … Read more
Risks of shoulder replacement surgery higher than previously thought
The risks associated with shoulder replacement surgery for arthritic conditions are higher than previously estimated, particularly for people under 60 and over 85 years old, according to a study supported by the NIHR Oxford BRC. The findings show that one in four men aged 55-59 years is at risk of needing further revision surgery, especially … Read more
World’s first gene therapy operation for common cause of sight loss carried out
Researchers in Oxford have carried out the world’s first gene therapy operation to tackle the root cause of age-related macular degeneration (AMD), the UK’s most common cause of sight loss. The procedure was carried out at the John Radcliffe Hospital by Prof Robert MacLaren, Professor of Ophthalmology at the University of Oxford, with the support … Read more
New project to accelerate clinical trial recruitment
A new project, led by the University of Oxford, will use NHS data to accelerate recruitment into clinical trials and increase the opportunities for NHS patients to participate in research. Every NHS hospital keeps a detailed record of activities. A monthly report is sent to NHS Digital, who host the data in trust for the … Read more
Only “modest” improvement in heart failure survival rates since 2000
Survival after a diagnosis of heart failure in the United Kingdom has shown only modest improvement in the 21st Century and lags behind other serious conditions, such as cancer, a large study supported by the Oxford Biomedical Research Centre has found. The findings, published by the BMJ, also show that survival is worse for people … Read more
Blog looks at Oxford BRC Health Impact symposium
In November 2018, the NIHR Oxford BRC jointly organised an international symposium to discuss how to maximise the impact of medical research. Some 87 delegates from eight countries took part in the symposium, ‘In the Trenches: Research Translation for Health Impact’, at Jesus College, Oxford. Now, two of the delegates, Alex Rushforth, of the Nuffield … Read more
New research to investigate role of blood-brain barrier in neurological conditions
A new consortium of 27 international partners from academia, industry, and small and medium enterprises, aims to tackle the unmet challenge of discovery and characterisation of blood-brain barrier targets and transport mechanisms for brain delivery of therapeutics to treat neurodegenerative and metabolic diseases. The new funding builds on previous research funded by the NIHR Oxford … Read more
Study suggests immune system plays key role in survival after pancreatic cancer surgery
Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells – may play an important role in survival after surgery to remove pancreatic cancer. The study by the University of Oxford’s Department of Oncology and Kennedy Institute, supported by the NIHR Oxford Biomedical Research … Read more
Oxford researchers develop new technique to analyse cancer cells’ life history
A team of researchers from the University of Oxford has developed a new technique that allows scientists to reliably track genetic errors in individual cancer cells, and find out how these might lead to uncontrollable growth. The research by the MRC Weatherall Institute of Molecular Medicine, supported by the NIHR Oxford Biomedical Research Centre, could … Read more
Researchers worried that people with chronic disease are not active enough
A study of over 96,000 men and women in the UK, with an average age of 64.5 years, has found that those with chronic conditions are spending considerably less time on physical activity than their healthy peers, and so are missing out on its health management benefits. The George Institute for Global Health at the … Read more
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