High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including ‘brain fog'. The findings give a major clue as to one cause of their symptoms: blood clots. Researchers from the University of Oxford looked at blood tests from ... READ MORE
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New Pharmacy Clinical Trials Unit paves way for trialling new therapies
Oxford University Hospitals’ (OUH) ability to help develop ground-breaking new therapies has been given a boost with the opening of a new temporary Pharmacy Clinical Trials Unit (CTU). Based on the Churchill Hospital site, the facility will be used to handle and prepare a new range of medicines ... READ MORE
Tumour monocyte content can predict immunochemotherapy outcomes, study shows
A team of Oxford researchers has discovered a link between immune cells known as monocytes in tumours and overall survival in patients with oesophageal cancer. A study by Ludwig Cancer Research, supported by the NIHR Oxford Biomedical Research Centre (BRC) found that the presence of relatively ... READ MORE
Research profile: Clinical nurses helping to shape our medical knowledge
Yuhan Zhang is an Advanced Nurse Practitioner in Oxford University Hospitals’ Ambulatory Outreach Team. She is also in the second year of a nursing doctorate at Oxford Brookes University, for which she is getting support from the NIHR Oxford Biomedical Research Centre (BRC). Yuhan works in an ... READ MORE
Real-world vaccine response in patients with impaired immune systems revealed
Updated data from the ongoing OCTAVE study reveal, for the first time, the real-world vaccine responses and infection outcomes in clinically at-risk patients with a range of immunocompromised or immunosuppressed conditions. Preliminary data from the landmark OCTAVE study in August 2021 showed ... READ MORE
Rapid weight loss found to be safe and helpful for people with liver disease
A clinical trial has shown that a three-month rapid weight loss programme was not only safe but also effective in reducing the severity of a liver disease called non-alcoholic steatohepatitis (NASH) with liver fibrosis. Results of the trial, which showed that improvements were maintained beyond ... READ MORE
OUH receives £3.4m for cutting-edge research equipment
Oxford University Hospitals (OUH) has received £3.4 million to fund state-of-the-art research equipment that will enable scientific discoveries and new technologies to improve the prevention, management and treatment of disease. The funding was part of the £96 million awarded by the National ... READ MORE
New imaging method trialled for retinal diseases
Clinical scientists in Oxford have presented a new method of imaging of the retina that overcomes many of the drawbacks of the current standard way of diagnosing and monitoring retinal diseases like age-related macular degeneration (AMD). The study, whose findings were published in the journal ... READ MORE
New antibiotic bone cement found not to reduce infection after hip fracture surgery
A large study has found that using high-dose dual-antibiotic loaded cement is unlikely to reduce the risk of infection in people who have had hip replacement surgery for their hip fracture. Bone cement is commonly used to fix surgical implants to the patient’s bone during hip replacement. In ... READ MORE
Shoulder replacement patients fare better with surgeons who do more operations
Patients treated by surgeons who average more than 10 shoulder replacements a year have a lower risk of further operations and serious complications, and a shorter hospital stay than those treated by surgeons who do fewer operations, according to a study by Oxford researchers. These findings, ... READ MORE
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