Oxford researchers have found a correlation between deaths from COVID-19 infections and a poorly coordinated systemic immune response, as well as increased activity by Mucosal Associated Invariant T cells, or ‘MAIT cells’. A study involving Oxford BRC-supported researchers published ... READ MORE
Researchers develop algorithm to diagnose deep vein thrombosis
Researchers are developing an artificial intelligence (AI) algorithm to diagnose deep vein thrombosis (DVT) more quickly and as effectively as traditional radiologist-interpreted diagnostic scans, potentially cutting down long patient waiting lists and avoiding patients unnecessarily receiving drugs ... READ MORE
Next generation of healthcare leaders showcase projects
The second edition of the NIHR Oxford BRC’s Next Generation Leaders Programme came to a successful close on 6 September with course participants presenting the healthcare research quality improvement projects that had been working on. The Next Generation Leaders Programme has been commissioned ... READ MORE
British Heart Foundation Cardiovascular Catalyst Awards
The BHF are pleased to announce an upcoming call for applications to fund research into the use of advanced analytics to improve cardiovascular care delivery and outcomes in the NHS. A £1 million fund is available, and proposals for research projects lasting up to two years and costing up to ... READ MORE
Study investigates responses to COVID-19 treatment in chronic lymphoid leukaemia patients
The COVID-19 pandemic has led to understandable anxiety within the blood cancer community about how their illness may affect their ability to overcome COVID-19 infection. Members of the Oxford Centre for Haematology have led a collaborative research project looking at the response of patients ... READ MORE
Lowering blood pressure still beneficial for the heart in old age
Oxford University researchers have found that blood pressure medication is still effective at reducing the risk of a heart attack and stroke in old age, even if blood pressure is in an apparently healthy range. The research by Professor Kazem Rahimi, who is supported by the NIHR Oxford ... READ MORE
New study launched to understand vaccine escape
Oxford researchers will be involved in a major new study seeking to understand why some people become infected after vaccination or prior infection while others do not Oxford BRC-supported investigators already involved in the Protective Immunity from T-Cells in Healthcare workers (PITCH) study ... READ MORE
Vaccination still best protection, but less effective against Delta variant, study finds
The latest findings of an ongoing national study of COVID-19 immunity in households across the UK has found that the Pfizer-BioNTech and Oxford-AstraZeneca vaccines offer good protection against new infections of the Delta variant of concern, but that effectiveness is reduced compared with the Alpha ... READ MORE
Second study confirms benefits of budesonide in early stages of COVID-19
A UK-wide clinical study has confirmed the findings of an earlier Oxford BRC-supported study showing that the early treatment with the inhaled asthma medication budesonide speeds up recovery from COVID-19 and reduces the risk of hospitalisation and death. The latest study – part of the PRINCIPLE ... READ MORE
Consultation on the draft NIHR Oxford Biomedical Research Centre Patient and Public Involvement and Engagement Strategy (2022-2027)
We are undertaking a public consultation on the draft Oxford Biomedical Research Centre (BRC) Patient and Public Involvement and Engagement (PPIE) Strategy (2022-2027). The consultation runs until 12th September 2021. In order to hear views from a diverse range of people, we ... READ MORE
First person receives drug designed to re-sensitise patients to cancer treatment
The first patient has been dosed using a new drug aimed at improving treatment options for melanoma and non-small cell lung cancer (NSCLC) and re-sensitising patients with checkpoint therapy-resistant tumours The IMP-MEL clinical trial began in Oxford with its first patient being dosed with the ... READ MORE
BRC-supported study receives Best Research Paper Award
A leading cardiology journal has named an academic paper written by Oxford BRC-supported researchers as its best research paper of 2020. The paper – which found that two common heart medication do not increase the risk of COVID-19 hospitalisation – was named by the BMJ Heart journal as the ... READ MORE
Oxford BRC takes part in NIHR initiative to promote race equality in health research
The Oxford Biomedical Research Centre (BRC) is to take part in a three-month reflective assessment of its delivery of race equality in health research, starting this month. The initiative, led by the NIHR, involved 13 organisations delivering health research in higher education, local ... READ MORE
Context important in assessing gender equity in BRCs
A study by NIHR Oxford Biomedical Research Centre researchers has concluded that the markers of achievement for monitoring gender equity in BRCs should take into account contextual factors specific to BRCs and women’s career progression and professional advancement. The study, published as a ... READ MORE
Liver problems common among COVID-19 patients, study finds
A study by Oxford University researchers has found that liver problems are common among patients with COVID-19. Patient data revealed that baseline hypoalbuminemia (an possible indication that the liver is producing low levels of albumin) and rising alkaline phosphatase (ALP), which can be a ... READ MORE
Oxford studies benefit from government funding of long COVID research
Thousands of people suffering with long COVID will benefit from new research programmes backed by £19.6 million to help better understand the condition, improve diagnosis and find new treatments. Among the 15 studies that will receive government funding through the National Institute for Health ... READ MORE
COVID-19 risk prediction tool wins national award
A COVID-19 risk prediction tool, developed with support from the NIHR Oxford Biomedical Research Centre (BRC) has won the Florence Nightingale Award for Excellence in Healthcare Data Analytics. The QCovid® COVID-19 Population Risk Assessment tool was developed by a cross-organisational team and ... READ MORE
Oxford Cancer launched at the University of Oxford
Oxford Cancer has been launched to represent and coordinate cancer research in Oxford. The pan-divisional initiative has been launched at the University of Oxford, bringing together the collective force of cancer research, outreach and care that happen across the city. With more than 900 ... READ MORE
Antiviral drug could be given to more chronic hepatitis B patients, study finds
A study by Oxford University researchers has found that the antiviral drug TDF may benefit a greater number of patients with chronic hepatitis B virus, and that those who are untreated may be at greater risk of liver inflammation and fibrosis. The research was carried out under the auspices of ... READ MORE
“Modest” increase in heart attack hospitalisation rates after years of decline
The burden of hospital admission rates due to heart attacks in England rose between 2012 and 2016, despite decades of falling rates, new research suggests. The researchers also found that after 2010-2011, admission rates increased in most age groups. Young women aged 35 to 49 and even younger ... READ MORE
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