The world’s largest clinical trial investigating treatments for COVID-19 has now been launched in South Africa, with the first patient recruited today. Since March 2020, the RECOVERY Trial, which is supported by the NIHR Oxford BRC, has discovered three effective treatments for COVID-19: the ... READ MORE
Study shows extent of BRC’s publications and collaborations
An analysis of the NIHR Oxford Biomedical Research Centre’s (BRC) publications between 2012 and 2017 has revealed not only the large number of research publications by its researchers, but also the huge network of collaborations in which they were involved. The study, published in the Journal ... READ MORE
Blog: the implications of the OxVALVE-Survive study on GP practice
Academic GPs Dr Clare Taylor and Dr Nick Jones (pictured) from the University of Oxford’s Nuffield Department of Primary Care Health Sciences outline the findings of the OxVALVE-Survive study and implications for their own clinical practice. Valvular heart disease occurs when valves become either ... READ MORE
OUH children’s diabetes service featured on One Show
An innovative new treatment for children with type 1 diabetes that is offered at the Oxford Children’s Hospital has been featured on primetime BBC television. The report shown on The One Show featured six-year-old patient Maebh, who has been fitted with a hybrid closed-loop system, also known ... READ MORE
Blood pressure drugs could protect against type 2 diabetes
Lowering high blood pressure is an effective way to reduce a person’s risk of developing type 2 diabetes in the future, according to a new study. Doctors already prescribe blood pressure-lowering drugs to reduce a person’s chance of having a life-threatening heart attack or stroke, but whether ... READ MORE
Whole genome sequencing improves diagnosis of rare diseases, study says
A world-first scientific study has shown that whole genome sequencing (WGS) can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS. The pilot study of rare undiagnosed diseases, published today in ... READ MORE
Genetic study highlights links between IBS and mental health disorders
Research funded and supported by the NIHR has revealed that symptoms of irritable bowel syndrome (IBS) may be caused by the same biological processes as mental health conditions such as anxiety. IBS is a common condition worldwide, affecting around 1 in 10 people. The condition causes a wide ... READ MORE
Study uncovers gene that doubles risk of death from COVID-19
University of Oxford researchers have identified the gene responsible for doubling the risk of respiratory failure from COVID-19. Sixty percent of people with South Asian ancestry carry the high-risk genetic signal, which could partly explain the excess deaths seen in some UK communities, ... READ MORE
New PPIE Strategy launched by Oxford BRC
The NIHR Oxford Biomedical Research Centre’s (Oxford BRC) patient and public involvement and engagement (PPIE) strategy 2022-2027 is now finalised and can be viewed from our PPIE Strategy page. The strategy aims to deliver excellent PPIE in collaboration with researchers and PPIE contributors. ... READ MORE
New therapeutic targets identified to treat inflammatory bowel disease
A new study by University of Oxford researchers has identified potential new therapeutic targets for the treatment of inflammatory bowel disease (IBD), giving hope to millions of patients with ulcerative colitis or Crohn’s disease. The research team from the University’s Kennedy Institute of ... READ MORE
QCOVID study identifies vaccinated groups at highest risk hospitalisation and death
Researchers from the University of Oxford have identified which vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death, from 14 days after the second dose of vaccination, when substantial immunity should be expected. The research used the QCovid tool, ... READ MORE
Prof Trish Greenhalgh named member of US National Academy of Medicine
Professor Trish Greenhalgh, the NIHR Oxford BRC’s Theme Lead for Partnerships for Health, Wealth and Innovation has been named a member of the US National Academy of Medicine (NAM). Election to the Academy is considered one of the highest honours in the field of health and medicine and recognises ... READ MORE
Largest ever global study of tuberculosis identifies genetic causes of drug resistance
Using cutting-edge genomic sequencing techniques, researchers at the University of Oxford have identified almost all the genomic variation that gives people resistance to 13 of the most common tuberculosis (TB) drug treatments. The Comprehensive Resistance Prediction for Tuberculosis ... READ MORE
Black History Month talk explores health inequalities
To mark Black History Month, the NIHR Oxford Biomedical Research Centre (BRC) sponsored an online talk by the health activist, social commentator and cultural historian, Patrick Vernon OBE on the subject of Inequalities in Healthcare and Research. In the University of Oxford Medical ... READ MORE
Your Path in Research – Colin Forde
The NIHR’s Your Path in Research campaign aims to encourage healthcare professionals to get involved in research or to further their career in research. Colin Forde is a physiotherapist at Oxford University Hospitals’ orthopaedic trauma outpatient department. He is completing a NIHR Doctoral ... READ MORE
Your Path in Research – Sheera Sutherland
The NIHR’s Your Path in Research campaign aims to encourage healthcare professionals to get involved in research or to further their career in research. Sheera Sutherland is a research nurse manager in the Oxford Kidney Unit. She completed an Oxford BRC preparatory fellowship in 2018 and is about to ... READ MORE
Your Path in Research – Joanna Snowball
The NIHR’s Your Path in Research campaign aims to encourage healthcare professionals to get involved in research or to further their career in research. Joanna Snowball has worked as a dietitian at Oxford University Hospitals since 2005, and for most of that time at the Oxford Adult Cystic Fibrosis ... READ MORE
RECOVERY Trial paper wins BMJ’s Research Paper of the Year Award
The RECOVERY Trial, the world’s largest randomised trial of potential COVID-19 treatments, has been announced as the 2021 winner of The British Medical Journal’s prestigious UK Research Paper of the Year Award. The award recognises original UK research that has the potential to ... READ MORE
New atlas reveals pre-birth development of blood cells in bone marrow
A new study has provided the most detailed analysis so far of the prenatal development of blood and immune cells in the bone marrow. The study, published in Nature, is part of the Human Cell Atlas (HCA) initiative to provide comprehensive reference maps of every cell type in the human ... READ MORE
Moonshot initiative to develop affordable COVID-19 antivirals gets funding boost
The COVID Moonshot, a non-profit, open-science consortium of scientists from around the world dedicated to the discovery of globally affordable and easily-manufactured antiviral drugs against COVID-19 and future viral pandemics has received key funding of £8 million from the Wellcome Trust, on ... READ MORE
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