A pioneering clinical trial for people with a sleep disorder that puts them at higher risk of developing Parkinson’s has recruited its first UK participant. The trial involves 40 people with iRBD (idiopathic REM sleep behaviour disorder), recruited from the Discovery Cohort study at the ... READ MORE
Study identifies key immune structures in the gut that may drive coeliac disease
Researchers in Oxford have found structures of immune cells in the gut that may be driving the response to gluten in people with coeliac disease and could provide a target for future therapies. The team from the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre ... READ MORE
New guidelines published for monitoring IBD patients to prevent bowel cancer
Researchers and clinicians have developed major new guidelines for the monitoring of patients with inflammatory bowel disease (IBD) to prevent them going on to develop bowel cancer. The new guidelines, developed for the British Society of Gastroenterology by academics at the Universities of ... READ MORE
New study finds common virus may improve skin cancer treatment outcomes
A new study led by University of Oxford researchers has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments. Cytomegalovirus (CMV) is a common virus that, while typically asymptomatic, is carried for life by 50 to 60 ... READ MORE
New research highlights colorectal cancer trends and survival rates
A study has shed light on the incidence and survival rates of colorectal cancer (CRC) in the UK, offering healthcare decision-makers crucial insights for planning, management and screening for the disease. The study, published in the American Journal of Gastroenterology, involved researchers from ... READ MORE
Study identifies direct link between inflammation and asthma attacks
An international consortium of respiratory scientists has highlighted the key role inflammation plays in asthma and offered a new approach to predict and prevent these attacks. The study by the ORACLE2 consortium, published in The Lancet Respiratory Medicine, was led by research clinician Simon ... READ MORE
BRC interns complete first stage of their research journey
Six Oxford University Hospitals (OUH) healthcare professionals have taken their first steps on the clinical academic pathway after presenting the results of their five-month NIHR Oxford Biomedical Research Centre (BRC) internship research projects. The internships are aimed at nurses, ... READ MORE
Study finds no benefit of routine use of cerebral embolic protection devices on TAVI stroke risk
Using cerebral embolic protection devices during transcatheter aortic valve implantation (TAVI) procedures does not reduce a patient’s risk of experiencing a stroke, according to a large UK clinical trial led by researchers from the Radcliffe Department of Medicine (RDM) and Oxford University ... READ MORE
Oxford launches first human aerosol TB challenge trial
The University of Oxford has begun a new clinical trial that aims to test tuberculosis (TB) vaccine safety and the host immune response in a first-in-man aerosol mycobacterial challenge infection model. The TB045 trial is being conducted with healthy adult volunteers in partnership with ... READ MORE
RECOVERY Trial team win NIHR Impact Prize
The RECOVERY Trial team have won a National Institute of Health and Care Research (NIHR) Impact Prize in the ‘established investigator’ category. The RECOVERY Trial, which has just recruited its 50,000th participant, was set up with support from the NIHR Oxford Biomedical Research ... READ MORE
NIHR recognises Oxford BRC researcher with Senior Investigator title
NIHR Oxford BRC Professor Sarah Walker has received a prestigious national research award. Professor Walker, Professor of Medical Statistics and Epidemiology at the Nuffield Department of Medicine and Oxford BRC Theme Lead for Modernising Medical Microbiology and Big Infection Diagnostics, has ... READ MORE
“We need clear pathways and structured support for allied health professionals to pursue a research career”
Miriam Lacharie is a diagnostic radiographer in the Oxford Centre for Clinical Magnetic Resonance Research (OCMR). In June 2024, she received a predoctoral award from the NIHR Oxford BRC and is currently researching imaging markers to predict disease progression in the genetic heart condition ... READ MORE
New Oxford women researchers’ network launched
A new network to support women and gender non-conforming researchers and staff in mid- and senior-level positions to develop as research leaders has been launched. The network, ASCEND, aims to support women and gender non-conforming researchers across the University of Oxford’s Medical Sciences ... READ MORE
Study finds previously unidentified genetic determinants of rare disease
A landmark study involving Oxford researchers has identified 69 previously unidentified genetic determinants of rare disease, including uncommon forms of epilepsy and schizophrenia. The multicentre research, led by Queen Mary University of London and including a number of researchers supported ... READ MORE
BLOG: Collaborate to include: how our EDI coordinators are catalysing and strengthening EDI activities
Mili Kalia, EDI manager, NIHR Oxford Biomedical Research Centre Working together with partners and stakeholders is a cornerstone of our BRC EDI strategy. Our core mission states that we “will engage and partner with BRC Stakeholders to catalyse and strengthen EDI activities”. This was one of ... READ MORE
“It gives you breathing space and the confidence to step into a leadership role”
Megha Agarwal is a clinical research fellow in the University of Oxford’s Radcliffe Department of Medicine (RDM). She took part in the Women in Leadership training course organised by the NIHR Oxford BRC’s Cardiovascular Theme, the first such training provided by the BRC specifically aimed at ... READ MORE
At-home test could play key role in type-1 diabetes screening
A new home test to diagnose type-1 diabetes (T1D) is being investigated in a major UK study led by researchers at the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre. The study will invite 90 children and young people across two groups to assess the test ... READ MORE
New scheme aims to give boost to NMAHPPs’ research careers
Six people have become the first OUH staff to take part in a new scheme to support nurses, midwives, allied health professionals, healthcare scientists, pharmacy staff and psychologist (NMAHPPs) in developing their career in research. The NIHR Oxford Biomedical Research Centre (BRC) is ... READ MORE
“It pushes you out of your comfort zone to talk about issues that women face in their roles”
Catherine Krasopoulos is lead nurse for the Cardiovascular Medicine Division in the University of Oxford’s Radcliffe Department of Medicine. She took part in the Women in Leadership training course organised by the NIHR Oxford BRC’s Cardiovascular Theme. Catherine is based in the Oxford Centre ... READ MORE
New Diversity in Research Group members get to know how they will make a difference
New members the NIHR Oxford and Oxford Health BRCs’ Diversity in Research Group attended a meeting on 31 January to learn about the work of the two BRCs and how they can play a crucial role in making research more reflective of the society it seeks to help. The Diversity in Research Group was ... READ MORE
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