A new Oxford-based drug-discovery company has been launched with the aim of developing targeted therapies for a specific family of blood cancers. Alethiomics was founded by Oxford BRC-supported researchers Professor Adam Mead and Professor Beth Psaila, with support from Oxford ... READ MORE
Archives for 2021
Doctors making AI-assisted decisions more accurate and confident in decision-making
New research has shown that doctors who use an artificial intelligence (AI) algorithm to assess echocardiograms are more accurate and more confident in their decision making. The study, published in the journal JACC Cardiovascular Imaging, is the first to show that an algorithm can ... READ MORE
Drug could more effectively treat patients hospitalised with COVID-19 pneumonia, research finds
A proof-of-concept trial involving Oxford researchers has identified a drug that may benefit some patients hospitalised with COVID-19 pneumonia. The CATALYST Trial tested the rheumatoid arthritis treatment namilumab as a potential therapeutic to treat patients who are hospitalised with COVID-19 ... READ MORE
People with long COVID after hospitalisation face limited recovery after one year
People who were hospitalised with COVID-19 and continued to experience symptoms five months later show limited further recovery one year after hospital discharge, according to the latest results of a major national study looking at the long-term health impacts of COVID-19 on hospitalised ... READ MORE
COVID-19 infection more likely than vaccines to cause rare cardiovascular complications
Researchers have reported the results of the largest ever study to compare the risks of cardiovascular events - such as myocarditis, pericarditis, and cardiac arrhythmia - between different vaccines and COVID-19 infection, and the first to investigate the association between cardiac events and the ... READ MORE
RECOVERY Trial launched in South Africa
The world’s largest clinical trial investigating treatments for COVID-19 has now been launched in South Africa, with the first patient recruited today. Since March 2020, the RECOVERY Trial, which is supported by the NIHR Oxford BRC, has discovered three effective treatments for COVID-19: the ... READ MORE
Study shows extent of BRC’s publications and collaborations
An analysis of the NIHR Oxford Biomedical Research Centre’s (BRC) publications between 2012 and 2017 has revealed not only the large number of research publications by its researchers, but also the huge network of collaborations in which they were involved. The study, published in the Journal ... READ MORE
Blog: the implications of the OxVALVE-Survive study on GP practice
Academic GPs Dr Clare Taylor and Dr Nick Jones (pictured) from the University of Oxford’s Nuffield Department of Primary Care Health Sciences outline the findings of the OxVALVE-Survive study and implications for their own clinical practice. Valvular heart disease occurs when valves become either ... READ MORE
OUH children’s diabetes service featured on One Show
An innovative new treatment for children with type 1 diabetes that is offered at the Oxford Children’s Hospital has been featured on primetime BBC television. The report shown on The One Show featured six-year-old patient Maebh, who has been fitted with a hybrid closed-loop system, also known ... READ MORE
Blood pressure drugs could protect against type 2 diabetes
Lowering high blood pressure is an effective way to reduce a person’s risk of developing type 2 diabetes in the future, according to a new study. Doctors already prescribe blood pressure-lowering drugs to reduce a person’s chance of having a life-threatening heart attack or stroke, but whether ... READ MORE
Whole genome sequencing improves diagnosis of rare diseases, study says
A world-first scientific study has shown that whole genome sequencing (WGS) can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS. The pilot study of rare undiagnosed diseases, published today in ... READ MORE
Genetic study highlights links between IBS and mental health disorders
Research funded and supported by the NIHR has revealed that symptoms of irritable bowel syndrome (IBS) may be caused by the same biological processes as mental health conditions such as anxiety. IBS is a common condition worldwide, affecting around 1 in 10 people. The condition causes a wide ... READ MORE
Study uncovers gene that doubles risk of death from COVID-19
University of Oxford researchers have identified the gene responsible for doubling the risk of respiratory failure from COVID-19. Sixty percent of people with South Asian ancestry carry the high-risk genetic signal, which could partly explain the excess deaths seen in some UK communities, ... READ MORE
New PPIE Strategy launched by Oxford BRC
The NIHR Oxford Biomedical Research Centre’s (Oxford BRC) patient and public involvement and engagement (PPIE) strategy 2022-2027 is now finalised and can be viewed from our PPIE Strategy page. The strategy aims to deliver excellent PPIE in collaboration with researchers and PPIE contributors. ... READ MORE
New therapeutic targets identified to treat inflammatory bowel disease
A new study by University of Oxford researchers has identified potential new therapeutic targets for the treatment of inflammatory bowel disease (IBD), giving hope to millions of patients with ulcerative colitis or Crohn’s disease. The research team from the University’s Kennedy Institute of ... READ MORE
QCOVID study identifies vaccinated groups at highest risk hospitalisation and death
Researchers from the University of Oxford have identified which vaccinated people are at greatest risk from severe Covid-19 leading to hospitalisation or death, from 14 days after the second dose of vaccination, when substantial immunity should be expected. The research used the QCovid tool, ... READ MORE
Prof Trish Greenhalgh named member of US National Academy of Medicine
Professor Trish Greenhalgh, the NIHR Oxford BRC’s Theme Lead for Partnerships for Health, Wealth and Innovation has been named a member of the US National Academy of Medicine (NAM). Election to the Academy is considered one of the highest honours in the field of health and medicine and recognises ... READ MORE
Largest ever global study of tuberculosis identifies genetic causes of drug resistance
Using cutting-edge genomic sequencing techniques, researchers at the University of Oxford have identified almost all the genomic variation that gives people resistance to 13 of the most common tuberculosis (TB) drug treatments. The Comprehensive Resistance Prediction for Tuberculosis ... READ MORE
Black History Month talk explores health inequalities
To mark Black History Month, the NIHR Oxford Biomedical Research Centre (BRC) sponsored an online talk by the health activist, social commentator and cultural historian, Patrick Vernon OBE on the subject of Inequalities in Healthcare and Research. In the University of Oxford Medical ... READ MORE
Your Path in Research – Colin Forde
The NIHR’s Your Path in Research campaign aims to encourage healthcare professionals to get involved in research or to further their career in research. Colin Forde is a physiotherapist at Oxford University Hospitals’ orthopaedic trauma outpatient department. He is completing a NIHR Doctoral ... READ MORE
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