A new home test to diagnose type-1 diabetes (T1D) is being investigated in a major UK study led by researchers at the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre. The study will invite 90 children and young people across two groups to assess the test ... READ MORE
News for Metabolic Experimental Medicine
Collaboration evaluates new drug for treatment of autonomous cortisol secretion
Scientists from the Universities of Oxford and Sheffield are collaborating with the US biopharmaceutical company Sparrow Pharmaceuticals on DC-MACS a Phase 2 clinical study of the drug clofutriben to treat autonomous cortisol secretion (ACS). Clofutriben, also known as SPI-62, is produced by ... READ MORE
Importance of early blood glucose control for people with type 2 diabetes highlighted
Research led by scientists from the Universities of Oxford and Edinburgh has found that early good blood glucose control can minimise the lifetime risk of diabetes-related complications, including heart attacks, kidney failure and vision loss. These latest results from the UK Prospective ... READ MORE
Oxford wins funding to set up UK’s first registry of those at risk of type 1 diabetes
Oxford researchers have received funding to set up a UK registry for children and adults who are at risk of type 1 diabetes (T1D), by testing positive for diabetes autoantibodies. Diabetes autoantibodies are proteins that appear when the insulin-producing beta cells in the pancreas are damaged. ... READ MORE
Evaluation hears benefits and challenges of citizen science project
A three-year NIHR Oxford Biomedical Research Centre (BRC) citizen science research study looking at treatments for non-alcoholic fatty liver disease (NAFLD) entered its final stages with a final visit from a European evaluation team. The study by the Oxford BRC and the Oxford Centre for ... READ MORE
New NIHR Oxford Senior Research Fellows named
Researchers from a wide range of disciplines have been appointed to be the next cohort of NIHR Oxford Senior Research Fellows – seven mid-career researchers identified as having the potential to become future translational research leaders. As in previous years, the selection ... READ MORE
Blood collected through skin offers reliable testing method in children with type 1 diabetes
Transdermal sampling - collecting blood through the skin - is a reliable alternative to taking blood samples from a vein with a needle in children with type 1 diabetes (T1D), new research has found. The study by Oxford researchers is the first to test the acceptability of transdermal sampling ... READ MORE
Oxford receives European funding for paediatric diabetes research
Oxford researchers have received funding from a European programme to investigate how to best follow up children who are at risk of type 1 diabetes (T1D). Oxford will receive 433,000 euros as part of the EDENT1FI programme which aims to identify T1D at its pre-clinical stage in children in the ... READ MORE
Rapid weight loss found to be safe and helpful for people with liver disease
A clinical trial has shown that a three-month rapid weight loss programme was not only safe but also effective in reducing the severity of a liver disease called non-alcoholic steatohepatitis (NASH) with liver fibrosis. Results of the trial, which showed that improvements were maintained beyond ... READ MORE
My journey towards being a citizen scientist – Maria Buckley, Step Change project
The NIHR Oxford Biomedical Research Centre is part of STEP CHANGE, a three-year European Commission project to support five citizen science projects. The study being led by the BRC is looking at the role of steroid hormones in the treatment of non-alcoholic fatty liver disease (NAFLD), obesity and ... READ MORE
Study raises hope of pre-school type 1 diabetes screening programme
Researchers in Oxford have launched the first UK study in the general population to test for early markers of type 1 diabetes before children develop symptoms or need insulin. The study, which is being offered when children have their pre-school vaccination, involves a finger prick and a few ... READ MORE
OUH dietitian accepted onto NIHR pre-doctoral fellowship
An Oxford University Hospitals (OUH) dietitian specialising in adult cystic fibrosis has been awarded a national pre-doctoral fellowship, following career support from the Oxford Biomedical Research Centre (BRC). Joanna Snowball (pictured), who works in the Oxford Adult Cystic Fibrosis (CF) ... READ MORE
BRC researchers lead new project to help people into remission from type 2 diabetes
NIHR Oxford BRC academics are to lead a new £2.2 million project aimed at giving more people newly diagnosed with type 2 diabetes the chance of going into remission. Professors Susan Jebb and Paul Aveyard, from the BRC’s Obesity, Diet and Lifestyle Theme, will be joining forces with Diabetes UK ... READ MORE
OUH children’s diabetes service featured on One Show
An innovative new treatment for children with type 1 diabetes that is offered at the Oxford Children’s Hospital has been featured on primetime BBC television. The report shown on The One Show featured six-year-old patient Maebh, who has been fitted with a hybrid closed-loop system, also known ... READ MORE
Blood pressure drugs could protect against type 2 diabetes
Lowering high blood pressure is an effective way to reduce a person’s risk of developing type 2 diabetes in the future, according to a new study. Doctors already prescribe blood pressure-lowering drugs to reduce a person’s chance of having a life-threatening heart attack or stroke, but whether ... READ MORE
Data reveals COVID-19 risk factors for people with type 1 diabetes
The largest study of people with type 1 diabetes admitted to hospital with COVID-19 has found that those with higher body mass index (BMI), poorer kidney function and the presence of microvascular complications were at greater risk of death and/or admission to intensive care. However, the ... READ MORE
BRC’s European-funded citizen science metabolism project under way
A three-year European Commission project to fund five citizen science projects, including one run by the NIHR Oxford BRC to research metabolism, has got under way. The €2.2m STEP CHANGE project is funding citizen science projects seven European countries and one in Africa. Funded by the ... READ MORE
NIHR health talks feature during Oxford IF festival
The Oxford BRC has joined with other parts of the local National Institute of Health Research infrastructure to organise a series of online talks as part of this year’s Oxford IF science and ideas festival. The talks, by leading Oxford researchers, cover a wide range of topics, from diabetes to ... READ MORE
Eight BRC projects get RCF funding
Eight Oxford BRC proposals, many covering a number of themes, have been awarded NIHR Research Capability Funding (RCF) funding to take forward key areas of research. The selected projects that will be supported include: Developing a research centre devoted to urgent and acute careThe ... READ MORE
BRC gets European funding for citizen science metabolism project
The NIHR Oxford Biomedical Research Centre (BRC) has received more than €270,000 from the European Commission as a part of a multi-nation research project to promote citizen science. Oxford’s involvement will entail the BRC and the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) ... READ MORE