A large field study in Nepal has shown that a typhoid conjugate vaccine (TCV) developed in Oxford is over 81 percent effective in tackling the disease. A single dose of the vaccine was found to be safe and effective in reducing typhoid in children aged 9 months to 16 years in an endemic ... READ MORE
Platelet rich plasma found to be of no benefit in treating torn Achilles tendon
New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures. The Achilles tendon is the most common tendon rupture treated in hospitals. Patients face long periods unable to work or participate in sport as ... READ MORE
All-singing all-dancing research at the Oxford Science and Ideas Festival
Oxford BRC-supported researchers have been sharing stories from their work through music and dance at IF Oxford, the Oxford Science and Ideas Festival. As part of the festival’s programme of over 100 events, the Oxford BRC supported a dance performance for primary school children and their ... READ MORE
Promising therapy for common form of eczema identified in early-stage trial
A new therapy that targets the immune system has shown promise for treating atopic dermatitis, the most common form of eczema, in a trial led by University of Oxford scientists. The small initial study, published in the journal Science Translational Medicine, is the first trial in humans to ... READ MORE
Severe reactions to grief can be predicted and treated in the first months following a bereavement
Memory, coping strategies and resilience immediately following a loss have been shown to predict the path of a bereaved person’s grief according to new research. The study, published in the Journal of Consulting and Clinical Psychology, also suggested that clinical intervention in the ... READ MORE
Study lays groundwork for review of digital interventions to tackle loneliness
Researchers at the NIHR Oxford Biomedical Research Centre (BRC) have produced a protocol to carry out a review and meta-analysis of the various digital technology interventions to address the growing problem of loneliness. “Loneliness is an emerging public health problem, associated with social, ... READ MORE
Study probes effectiveness of efforts to involve patients and public in changing research agenda
Projects that involve patients and the public as a way of determining health research priorities vary considerably in the extent to which they influence what research is actually done, according to research supported by the NIHR Oxford Biomedical Research Centre. The research aimed to assess ... READ MORE
Researchers find new cells that repair tissue
Researchers at Oxford University have discovered that a newly discovered group of cells can help repair tissues in the body. The researchers, who are supported by the NIHR Oxford Biomedical Research Centre, say these cells, which are abundant in our bodies, could be harnessed to help heal ... READ MORE
Oxford haematologists win national awards to further their research
Two consultant haematologists at the Oxford Haemophilia and Thrombosis Centre (OHTC), based at the Churchill Hospital, have been awarded funding for their research as part of a new national scheme. Dr Nicola Curry and Dr Susie Shapiro were among the recipients of the new Clinical Academic ... READ MORE
Heart rate rise and blood pressure drops during pregnancy not as dramatic as previously thought
New analysis from over 36,000 healthy women in 20 countries suggests that physiological changes during pregnancy may not be as dramatic as traditionally taught. However, blood pressures do appear to be increasing year on year. Medical text books are based on data that is now over 40 years old. ... READ MORE
AI identifies ‘fingerprint’ that predicts heart attack risk
Oxford researchers have developed a new biomarker – derived through artificial intelligence analysis of routine CT scans – that can identify people at high risk of a fatal heart attack at least five years before it strikes. The researchers, who are supported by the NIHR Oxford Biomedical Research ... READ MORE
Heart failure care must address patients’ broader health if survival rates are to improve
Oxford BRC-supported researchers have provided new evidence that might explain why the prognosis of heart failure patients has improved so little over the past decade. Findings show that a decline in cardiovascular deaths has been offset by an increase in the number of deaths from infections and ... READ MORE
Future life sciences leaders immerse themselves in Oxford collaborations
A group of emerging health sector leaders taking part in a new national leadership programme have visited Oxford to learn about how academics, clinicians and industry partners are collaborating to drive innovation to benefit patients. The Immersion Day, which was organised by the NIHR Oxford ... READ MORE
Achieving Type 2 diabetes treatment targets would improve health and reduce healthcare costs
Improvements in health and reductions in healthcare costs could be achieved if blood glucose, blood pressure and cholesterol treatment targets were met. Researchers from the Nuffield Department of Population Health, University of Oxford, assessed the long-term impact of achieving treatment ... READ MORE
International students learn about Oxford’s neuroscience and diabetes research
Around 50 international students interested in a career in medicine or science have visited Oxford BRC-funded research facilities. Half the students, who are taking part in the London International Youth Science Forum (LIYSF), visited the John Radcliffe Hospital’s Neuroscience department, while ... READ MORE
Smartphone test predicts how symptoms develop in Parkinson’s
Researchers in Oxford have found that a simple test carried out on a smartphone can help to accurately predict future change in people in the early stages of Parkinson’s, helping to determine the support they may need. This study, supported by the NIHR Oxford Biomedical Research Centre (BRC) ... READ MORE
New approach to reducing damage after a heart attack
During the emergency procedure used to reopen the blocked artery that has caused a heart attack, smaller ‘micro’ blood vessels can remain constricted, causing significant damage, according to a new study. The research by Associate Professor Neil Herring of the University of Oxford’s Department of ... READ MORE
Study discovers genetic changes linked to leukaemia in children with Down’s syndrome
Researchers at the University of Oxford have discovered the specific gene mutations that are required for the development of leukaemia in children with Down’s syndrome. Children with Down’s syndrome have a 150-fold increased risk of myeloid leukaemia, and while some of the genetic causes of ... READ MORE
Research suggests high blood pressure is major cause of heart valve disease
New research has conclusively found that long-term exposure to high blood pressure increases the risk of heart valve disease, with significant implications for clinical practice guidelines and health management. “Clinical practice guidelines currently make little reference to preventative ... READ MORE
Oxford Blood Group: Exchange Newsletter Issue 3 vol 1 / June 2019
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