The combination of hydroxychloroquine (HCQ) and azithromycin (AZM) has been linked to significant cardiovascular risks, including mortality, in the largest safety study ever performed on both HCQ and HCQ+AZM. This network study, led by the Observational Health Data Sciences and Informatics ... READ MORE
Test developed to identify new-borns at risk of leukaemia
Oxford researchers have developed a new method to quickly identify cancerous cells in babies at risk of leukaemia. The team hope that the new protocol could make rapid testing more accessible for clinical laboratories around the globe. Until now, the only reliable way to know if a baby with ... READ MORE
Paper outlines management of post-acute COVID-19 in primary care
A new article published in the BMJ has mapped out what is known and what is still unknown about ‘long COVID’, where patients COVID-19 patients continue to experience symptoms many weeks after contracting the virus. The article, co-authored by the NIHR Oxford BRC’s Theme Lead for Partnerships ... READ MORE
Common heart medication does not increase risk of COVID-19 hospitalisation
A study by Oxford researchers, supported by the NIHR Oxford Biomedical Research Centre (BRC), found that ACE inhibitors and ARBs – both common treatments for high blood pressure and heart failure – are not generally linked to an increased risk of severe COVID-19 disease or an increased likelihood of ... READ MORE
BRC gets European funding for citizen science metabolism project
The NIHR Oxford Biomedical Research Centre (BRC) has received more than €270,000 from the European Commission as a part of a multi-nation research project to promote citizen science. Oxford’s involvement will entail the BRC and the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) ... READ MORE
Oxford University and ZOE partner on COVID-19 treatment trials
The University of Oxford has joined forces with the COVID Symptom Study app to widen access to two clinical trials of potential treatments for COVID-19. The two trials include the STOIC trial, which is supported by the NIHR Oxford BRC. Run by the University’s Nuffield Department of Medicine ... READ MORE
Study maps role CD8 T cells play in IBD
Researchers in Oxford using an ‘atlas’ of immune cells in the human colon have found evidence of the role of CD8 T cells in inflammatory bowel disease (IBD). The findings could lead to a better understanding of how cells behave and interact in people with IBD, and could pave the way for more ... READ MORE
Mild COVID-19 symptoms might not result in positive antibody test, research finds
Oxford researchers have found that COVID-19 antibody tests might not give a positive result if people have only had mild symptoms, like loss of taste and smell. Microbiology and data experts from the Oxford University Hospitals (OUH) NHS Foundation Trust and the University of Oxford made the ... READ MORE
BRC researchers’ work recognised with Vice-Chancellor’s Awards
A number of Oxford BRC-supported researchers have been recognised in this year’s University of Oxford Vice-Chancellor Innovation Awards. The Vice-Chancellor Innovation Awards celebrate research-led innovation that is having societal or economic impact. Prof Robert MacLaren, who leads the BRC’s ... READ MORE
AI test identifies COVID-19 within an hour in emergency departments
University of Oxford scientists specialising in infectious disease and clinical machine learning have developed an artificial intelligence test that can rapidly screen for COVID-19 in patients arriving in emergency departments. The initial findings of the ‘CURIAL’ AI test, which has been ... READ MORE
Photography exhibition on NHS research comes to Newbury
A travelling photography exhibition showcasing ground-breaking NHS research taking place across the Thames Valley has opened in Newbury. The exhibition, ‘The Body Unlocked: How Research is Changing Lives’, consists of two metre-high panels featuring people who have taken part in studies, ... READ MORE
New treatment reduces COVID-19 patients needing intensive care
The preliminary results of a clinical trial supported by NIHR Oxford BRC researchers have suggested that a new treatment for COVID-19 dramatically reduces the number of patients needing intensive care. The treatment, a protein called interferon beta, has been developed by the UK biotech company ... READ MORE
Oxford coronavirus vaccine produces strong immune response, study finds
A team of scientists at Oxford University’s Jenner Institute and Oxford Vaccine Group has taken the next step towards the discovery of a safe, effective and accessible vaccine against coronavirus. The results of the Phase I/II trial, published today in The Lancet, indicate no early safety ... READ MORE
Home colorectal cancer tests could prioritise patients for referral
Non-invasive home-based tests that detect blood in patient stool samples offer an accurate and appropriate triaging method for GPs, according to University of Oxford researchers. The study, which is already informing a redesign of the colorectal cancer pathway at Oxford University Hospitals (OUH) ... READ MORE
Thousands miss out on life-saving heart attack treatment due to COVID-19 pandemic
Researchers at the University of Oxford have published new research that shows that by the end of May there had been about 5,000 fewer hospital admissions with heart attack in 2020 than would be expected, suggesting that many patients have missed out on lifesaving treatment. The research showed ... READ MORE
New national study into the long-term health impacts of COVID-19
A major UK research study - PHOSP-COVID, will investigate the long-term health impacts of COVID-19 on hospitalised patients. The new study has been awarded £8.4 million jointly by UK Research and Innovation (UKRI) and the National Institute for Health Research (NIHR). The PHOSP-COVID study is ... READ MORE
New role highlights greater emphasis on nursing research
The appointment of its first ever Director of Nursing and Midwifery Research and Innovation signals Oxford University Hospital’s determination to highlight the important role nurses and other non-medical staff can play in research, and the fact that research can be an important career ... READ MORE
Varying risk of COVID-19 to health workers revealed
A study at Oxford University Hospitals (OUH) NHS Foundation Trust has revealed the different levels of risk faced by healthcare workers dealing with the COVID-19 pandemic. In a major collaboration with the University of Oxford, almost 10,000 staff were tested both for presence of the virus ... READ MORE
Oxford leads development of risk prediction model for smarter COVID-19 shielding advice
People at highest risk of serious illness from SARS-CoV-2 infection may soon have access to better shielding advice based on a new data-driven risk prediction model being developed by an Oxford University-led team. The Principal Investigator, Professor Julia Hippisley-Cox of the ... READ MORE
Breakthrough in RECOVERY COVID-19 drug treatment trial
A cheap and widely available steroid has been found to save lives of patients hospitalised with COVID-19 in a national trial being led by University of Oxford researchers. Dexamethasone was one of the drugs being tested as part of the RECOVERY trial, the world's biggest trial looking at whether ... READ MORE
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