Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the ... READ MORE
Oxford BRC statement on activities during the current COVID-19 situation
Many of the researchers we support are also clinicians, providing direct care to patients and the public, alongside their academic work. Given the scale of the national and global challenge of COVID-19 (coronavirus), BRC-funded clinical and research professionals who are working on topics ... READ MORE
Researchers identify markers in joint fluid that could be key to cartilage repair
Oxford researchers have found that molecular changes in the joint fluid during knee distraction surgery reveal markers that may drive cartilage repair in osteoarthritis. It is generally accepted that cartilage is not able to heal or regenerate itself after injury or through wear and tear, ... READ MORE
Athena SWAN “Europe’s most comprehensive gender equality scheme”
A study involving researchers from the NIHR Oxford Biomedical Research Centre (BRC) has found that institutions in the European Research Area could benefit from exploring Athena SWAN as the basis for their gender equality policies. The study found that Athena SWAN, with its ... READ MORE
New stroke research centre opens in Oxford
Research into strokes and vascular dementia took a major step forward on Thursday (5th March) with the official opening of the Wolfson Centre for the Prevention of Stroke and Dementia (CPSD) in Oxford, based at the new Wolfson Building at the John Radcliffe Hospital. The new centre is the only ... READ MORE
Top accolade for gestational diabetes app
A smartphone application for women with gestational diabetes, developed at Oxford University Hospitals (OUH) and the University of Oxford, has won a national award. GDm-Health won the MedTech, Device or Hardware Innovation Award at the HSJ Partnership Awards on Thursday (27th February). The ... READ MORE
Molecular Diagnostics theme hosts cancer genomics and immunology seminar
The Molecular Diagnostics theme hosted a very successful seminar, ‘Advanced personalised therapies in gynaecological cancers’, at St Hugh’s College in February 2020. The meeting covered the genomics and immunology of cancer along with the emerging topic of advanced therapeutic medicinal products ... READ MORE
Oxford BRC welcomes visitors to expand international links
The Oxford BRC has recently hosted leading healthcare groups from South Korea, Brazil and Turkey to expand its international links and identify opportunities for collaboration. During their visits, the foreign guests met the BRC management team, key researchers and industry partnership managers. ... READ MORE
Gene therapy shows promise in tackling common cause of childhood blindness
The results of a first-in-human clinical trial of gene therapy to treat a common cause of genetic blindness have shown partial reversal of sight loss in some patients. X-linked retinitis pigmentosa, caused by mutations in RPGR gene, is the most common cause of blindness in young people. The ... READ MORE
Oxford professors appointed NIHR Senior Investigators
Four leading healthcare academics in Oxford have received a prestigious national award. The University of Oxford professors were named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and prestigious researchers ... READ MORE
Working together to find a cure to HIV
Results from a study testing a new ‘kick and kill’ method of reducing the size of the undetected HIV reservoir in people living with the virus were published in The Lancet this week. RIVER (Research in Viral Eradication of HIV Reservoirs) is the first ever randomised clinical trial to test this ... READ MORE
Critical care nurse is first from OUH to get an NIHR clinical doctoral fellowship
A critical care research nurse based at the John Radcliffe Hospital has become the first Oxford University Hospitals nurse to receive funding for a PhD from the National Institute for Health Research (NIHR). Jody Ede, a sister in the Adult Intensive Care Unit and a researcher in the Kadoorie ... READ MORE
Link between high cholesterol and aortic valve disease risk found
Oxford researchers have found that while having high cholesterol levels does not influence a person’s risk of aortic or mitral regurgitation, it does increase their risk of developing another major heart valve disease - aortic stenosis. Aortic stenosis is the most common form of heart valve ... READ MORE
Exhibition on NHS research launched in Oxford
A photography exhibition showcasing ground-breaking NHS research taking place across the Thames Valley has been launched in Oxford. ‘The Body Unlocked: How Research is Changing Lives’ features life-sized photographs of people who have taken part in studies, researchers at work ... READ MORE
New trauma wound treatment no better than standard dressing
A study by Oxford researchers has shown that a new method of treating wounds after major trauma is no more effective at improving surgical infection rates than cheaper standard dressings. The findings, by a team at the Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal ... READ MORE
Almost half of chronic kidney disease is unrecognised
A study by Oxford researchers has found that more than 18 percent of over-60s have chronic kidney disease (CKD), around 44 percent of whom are undiagnosed without screening. CKD is a potentially serious condition, but is associated with few, if any, symptoms. It is thought to affect around 15 ... READ MORE
Short or long sleep associated with pulmonary fibrosis
Scientists have discovered that people who regularly sleep for very long (11 hours or more) or very short (four hours or less) periods of time are two to three times more likely to have the incurable disease pulmonary fibrosis, compared to those that sleep for seven hours in a day. The ... READ MORE
Oxford researchers test ‘Viagra’ drug to prevent recurrent strokes
University of Oxford researchers have begun a clinical trial to assess whether the drug sildenafil, more commonly known by its commercial name Viagra, could improve blood flow to the brain and so have the potential to reduce damage to small blood vessels in the brain and prevent ... READ MORE
Amount of sugar sold in soft drinks drops by 29% in the UK
There was a 29% reduction in the total amount of sugar sold in soft drinks in the UK between 2015-2018, despite an increase in sales of soft drinks by volume of 7%, according to new research supported by the NIHR Oxford BRC. The research, published in BMC Medicine, shows that individual soft ... READ MORE
Researchers identify link in the treatment of inflammatory bowel disease
A new study involving Oxford researchers has revealed how the anti-inflammatory cytokine IL-10 and lipid mediator prostaglandin E2 (PGE2) work together to prevent inflammatory tissue damage and maintain a healthy gut balance. Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) ... READ MORE
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