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You are here: Home > News listings for COVID-19

News for COVID-19

Study explores effects of COVID-19 on sleep

15 June 2020 · Listed under COVID-19, Neurological Conditions

Oxford researchers have launched a study investigating the impact of the COVID-19 pandemic on sleep and daily rhythms in adults. The UK arm of the International COVID-19 Sleep Study (ICOSS) is led by Professor Colin Espie from the Nuffield Department of Clinical Neurosciences at the University of Oxford and is funded by the NIHR Oxford … Read more

Oxford leads part of major COVID-19 drugs trial

10 June 2020 · Listed under COVID-19, Musculoskeletal

As part of a new UK trial researchers at the University of Oxford will investigate whether administering the anti-inflammatory drug infliximab to patients with COVID-19 can prevent progression to respiratory failure or death. The multi-arm, multi-stage CATALYST Trial, is being led by the University of Birmingham in partnership with University Hospitals Birmingham and the Birmingham NIHR Biomedical Research … Read more

First patient recruited for key drug treatment trial

4 June 2020 · Listed under COVID-19, Respiratory

A clinical trial to test whether Azithromycin, a commonly used antibiotic, can treat the symptoms of COVID-19 in outpatients has recruited its first patient. The ATOMIC2 trial, which is being led from Oxford, will enrol 800 people who are being assessed at hospital with COVID-19 but felt well enough to be cared for at home. … Read more

Drug trial could lead to enhanced respiratory care for COVID-19 patients

29 May 2020 · Listed under COVID-19, Respiratory

Researchers at the University of Oxford are working with clinical collaborators from NHS hospitals, including Oxford University Hospitals, to test a drug that could raise oxygen levels in the blood in COVID-19 patients in order to improve their chances of recovery. Raising oxygen levels is important in COVID-19, because many patients with the disease die … Read more

Oxford COVID-19 vaccine to begin phase II/III human trials

22 May 2020 · Listed under COVID-19, Vaccines for Emerging and Endemic Diseases

University of Oxford researchers have begun recruiting for the next phase in human trials of a COVID-19 vaccine in human volunteers. The phase I trial in healthy adult volunteers began in April. More than 1,000 immunisations have been completed and follow-up is currently ongoing. The next study will enrol up to 10,260 adults and children … Read more

BRC theme lead to study ‘remote-by-default’ care in COVID-19 pandemic

12 May 2020 · Listed under COVID-19, Partnerships for Health, Wealth and Innovation

A senior Oxford BRC investigator has received major government funding for a new study to support general practitioners to deliver effective remote care to their patients during the COVID-19 pandemic. Professor Trisha Greenhalgh (pictured right), of the University of Oxford’s Nuffield Department of Primary Care Health Sciences, was awarded £750,000 from the Economic and Social … Read more

Managing clinical trials in a pandemic: interview with Prof Duncan Richards

5 May 2020 · Listed under COVID-19

Duncan Richards

Professor Duncan Richards, who is Director of the Oxford Clinical Trials Research Unit (OCTRU) as well as the NIHR Oxford Biomedical Research Centre’s Musculoskeletal Co-theme Lead, is at the forefront of Oxford’s strategy on clinical trials for COVID-19. In this interview with the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), he discusses how … Read more

Oxford COVID-19 vaccine begins human trial stage

23 April 2020 · Listed under COVID-19, Vaccines for Emerging and Endemic Diseases

University of Oxford researchers have begun testing a COVID-19 vaccine in human volunteers in Oxford. Around 1,110 people will take part in the trial, half receiving the vaccine and the other half (the control group) receiving a widely available meningitis vaccine. Of the first two volunteers to take part, one likewise received the vaccine and … Read more

Large-scale COVID-19 infection and antibody test study launched

23 April 2020 · Listed under Antimicrobial Resistance and Modernising Microbiology, Clinical Informatics and Big Data, COVID-19

Some 20,000 households across England are being contacted to take part in the first wave of a major new government study to track the COVID-19 coronavirus in the general population. The study will help improve understanding around the current rate of infection and how many people are likely to have developed antibodies to the virus. … Read more

BRC funds three further COVID-19 studies

21 April 2020 · Listed under COVID-19, Gastroenterology and Mucosal Immunity, Haematology and Stem Cells, Vaccines for Emerging and Endemic Diseases

Three more studies are being funded by the NIHR Oxford Biomedical Research Centre (BRC) to look at the way the body interacts with COVID19; these include assessing the safety of a new vaccine; the role that antibodies might play in plasma therapy; and blood biomarkers that determine adverse reactions in those that have been infected. … Read more

Common antibody test can be adapted for COVID-19, study finds

20 April 2020 · Listed under Antimicrobial Resistance and Modernising Microbiology, COVID-19, Gastroenterology and Mucosal Immunity

Research led from Oxford has found that an immunological assay commonly used to measure antibodies, antigens and proteins in biological samples can be specifically adapted to detect and quantifying COVID-19 antibodies. The investigations by the National COVID Testing Scientific Advisory Panel were co-ordinated by Prof Derrick Crook at the University of Oxford. The trial involved researchers at … Read more

Oxford-led research describes the safety profile and potential harms of hydroxychloroquine and azithromycin

16 April 2020 · Listed under Clinical Informatics and Big Data, COVID-19

Over 300 researchers from the Observational Health Data Sciences and Informatics (OHDSI) international community studied data from almost 1 million patients who have previously taken hydroxychloroquine. They declared hydroxychloroquine safe for short-term use, but urge caution in using it in combination with azithromycin. Led by Prof Dani Prieto-Alhambra, Professor of Pharmaco- and Device Epidemiology at the … Read more

BRC funds new COVID-19 research projects

6 April 2020 · Listed under COVID-19, Imaging, Multimorbidity and Long-Term Conditions, Respiratory, Technology and Digital Health

The NIHR Oxford Biomedical Research Centre (BRC) has allocated funding to three COVID-19 research projects in an attempt to improve treatment, understand how the virus interacts with chronic diseases, and the longer-term effects of infection on organs. The funding, originally earmarked for BRC cross-theme cluster projects, has been diverted to research projects in the BRC’s … Read more

New wearable technology used to monitor COVID-19 patients

1 April 2020 · Listed under COVID-19, Technology and Digital Health

Wearable technology that monitors patients’ vital signs is being used with COVID-19 patients on the isolation ward at the John Radcliffe Hospital. The technology has been developed by biomedical engineers and medical researchers supported by the NIHR Oxford Biomedical Research Centre (BRC). The Oxford BRC’s Technology and Digital Health theme, led by Prof Peter Watkinson … Read more

GP practices urged to join COVID-19 research

30 March 2020 · Listed under Clinical Informatics and Big Data, COVID-19, Multimorbidity and Long-Term Conditions

Oxford researchers have launched a study to track the spread of COVID-19 in the population and develop a deeper understanding of the virus in general practice. The University of Oxford’s Nuffield Department of Primary Care Health Sciences (NDPCHS) and the Royal College of General Practitioners (RCGP) have joined forces with clinical system supplier EMIS Health … Read more

Oxford COVID-19 vaccine programme opens for clinical trial recruitment

27 March 2020 · Listed under COVID-19, Vaccines for Emerging and Endemic Diseases

University of Oxford researchers, working in an unprecedented vaccine development effort to prevent COVID-19, have started screening healthy volunteers ahead of a vaccine trial. The NIHR Oxford Biomedical Research Centre (BRC) provided essential funding to get the trial up and running. The team will enrol healthy volunteers aged between 18 and 55, who, if they … Read more

Article addresses remote assessment of COVID-19 in primary care

25 March 2020 · Listed under COVID-19, Partnerships for Health, Wealth and Innovation

An article by a leading Oxford researcher has outlined the guiding principles on how general practitioners should conduct remote consultations with patients who are suspected of having COVID-19. The article, published in the BMJ, is by Prof Trish Greenhalgh (pictured), the Oxford BRC Theme Lead for Partnerships for Health, Wealth and Innovation, and a Professor … Read more

Oxford researchers to play key role in fight-back against COVID-19

20 March 2020 · Listed under Antimicrobial Resistance and Modernising Microbiology, Clinical Informatics and Big Data, COVID-19, Gastroenterology and Mucosal Immunity, Partnerships for Health, Wealth and Innovation, Respiratory, Vaccines for Emerging and Endemic Diseases

Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the Oxford Vaccine Group and the University of Oxford’s Jenner … Read more

Oxford BRC statement on activities during the current COVID-19 situation

19 March 2020 · Listed under COVID-19, Other News

Many of the researchers we support are also clinicians, providing direct care to patients and the public, alongside their academic work. Given the scale of the national and global challenge of COVID-19 (coronavirus), BRC-funded clinical and research professionals who are working on topics other than COVID-19, or those with relevant skills, are being asked to … Read more

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