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Messaging focused on personal rather than collective benefits more effective for COVID-19 vaccination

13 May 2021 · Listed under COVID-19, Life-saving Vaccines

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The largest ever study of COVID-19 vaccine messaging shows that emphasising the personal benefits of vaccination may be the most effective way to persuade people who are sceptical about the jab. For the one in ten who say they won't take a COVID-19 vaccine, messaging that focuses on personal ... READ MORE

Oxford BRC researchers named among new Academy of Medical Sciences fellows

12 May 2021 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Preventive Neurology, Translational Data Science

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A number of leading researchers supported by the NIHR Oxford Biomedical Research Centre are among 50 prominent biomedical and health scientists elected to the Academy of Medical Sciences’ respected and influential Fellowship. The new Fellows include Oxford BRC experts who have spearheaded the ... READ MORE

Data reveals COVID-19 risk factors for people with type 1 diabetes

11 May 2021 · Listed under COVID-19, Metabolic Experimental Medicine, Translational Data Science

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The largest study of people with type 1 diabetes admitted to hospital with COVID-19 has found that those with higher body mass index (BMI), poorer kidney function and the presence of microvascular complications were at greater risk of death and/or admission to intensive care. However, the ... READ MORE

Study reveals three most important aspects of care for hip fractures

5 May 2021 · Listed under Musculoskeletal

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Older patients with hip fractures recover better if they receive treatment under the supervision of both a surgeon and a specialist in elderly care; are checked to avoid future falls; and are assessed for memory problems. These are the findings of the World Hip Trauma Evaluation (WHiTE) study, ... READ MORE

Foods linked to greater risk of cardiovascular disease and death in middle-age identified

4 May 2021 · Listed under Cardiovascular Medicine, Obesity, Diet and Lifestyle

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Two common dietary patterns identified in British adults may be associated with an increased risk of cardiovascular disease and death in middle-age, according to a study by Oxford University researchers. The research, which was supported by the NIHR Oxford Biomedical Research Centre, was ... READ MORE

More people could benefit from blood pressure-lowering medication, study finds

30 April 2021 · Listed under Cardiovascular Medicine, Multimorbidity and Long-Term Conditions, Preventive Neurology

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Blood pressure-lowering medication can prevent serious cardiovascular conditions such as strokes, heart failure and heart attacks, even in adults with normal blood pressure, according to a new research by University of Oxford researchers In a paper published in the Lancet, the researchers found ... READ MORE

Study highlights role of BMI in increased COVID-19 risks

29 April 2021 · Listed under COVID-19, Obesity, Diet and Lifestyle, Translational Data Science

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A study by University of Oxford researchers has found that the risk of admission to hospital, admission to ICU or death from COVID-19 increases progressively above a ‘normal’ BMI of 23, even without other comorbidities. The research team, who are supported by the NIHR Oxford Biomedical Research ... READ MORE

Study challenges idea of clinically significant mid-pregnancy drop in blood pressure

28 April 2021 · Listed under Digital Health from Hospital to Home

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An international study involving NIHR Oxford BRC researchers has shown where normal blood pressure in pregnancy should be across the world and when clinicians should react because it is abnormal. The study’s findings, published in PLOS Medicine, provide international, gestational age-specific ... READ MORE

Azithromycin not effective against COVID-19, trial confirms

26 April 2021 · Listed under COVID-19, Respiratory Medicine

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A clinical trial by University of Oxford researchers has confirmed that the antibiotic azithromycin has no clinical benefit in people with moderate COVID-19. The ATOMIC2 trial, which was supported by the NIHR Oxford Biomedical Research Centre (BRC), was established to investigate if a common ... READ MORE

Malaria vaccine becomes first to achieve WHO-specified 75% efficacy goal

26 April 2021 · Listed under Life-saving Vaccines

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Researchers from the University of Oxford and their partners have reported that a malaria vaccine they are developing has proved to be 77% effective in early trials. The findings of the Phase IIb randomised, controlled, double-blind trial, posted on SSRN/Preprints with The Lancet, show the ... READ MORE

National survey reveals big reductions in COVID-19 infections with single dose of Oxford-AZ and Pfizer vaccines

23 April 2021 · Listed under COVID-19, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics, Translational Data Science

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Data from the national COVID-19 Infection Survey, which is led by senior NIHR Oxford BRC researcher Professor Sarah Walker, has revealed the impact of vaccination on antibody responses and new infections in a large group of adults from the general population. This major community surveillance ... READ MORE

Human challenge trial launches to study immune response to COVID-19

19 April 2021 · Listed under COVID-19, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics

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Researchers at the University of Oxford have launched a human challenge trial to look at what kind of immune response can stop people from becoming re-infected. The team, led by the NIHR Oxford Biomedical Research Centre Director Professor Helen McShane (pictured right), also want to find out ... READ MORE

Getting Involved with the Oxford Biomedical Research Centre

15 April 2021 · Listed under Industry & Partnerships, Other News, Patient and Public Involvement and Engagement

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The NIHR Oxford Biomedical Research Centre (BRC) has been working with a group which includes teenagers, young adults, carers and people from black, Asian and minority ethnic communities.   The project is part of the development of a new strategy and had a particular focus on making health ... READ MORE

BRC’s European-funded citizen science metabolism project under way

13 April 2021 · Listed under Metabolic Experimental Medicine

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A three-year European Commission project to fund five citizen science projects, including one run by the NIHR Oxford BRC to research metabolism, has got under way. The €2.2m STEP CHANGE project is funding citizen science projects seven European countries and one in Africa. Funded by the ... READ MORE

New clinical prediction tools for myeloma developed

9 April 2021 · Listed under Cancer, Translational Data Science

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University of Oxford researchers have developed new clinical prediction models for use in primary care with the aim of accelerating the diagnosis of myeloma, a cancer of the bone marrow. Myeloma caused 117,077 deaths worldwide in 2020. Earlier diagnosis improves the rate of survival but ... READ MORE

National study looks at long-term lung damage from COVID-19

7 April 2021 · Listed under COVID-19, Respiratory Medicine

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A new national study involving researchers from Oxford will investigate the long-term effects of lung inflammation and scarring from COVID-19. The study, launched with £2 million of funding from UK Research and Innovation (UKRI), aims to develop treatment strategies and prevent ... READ MORE

Oxford BRC again achieves ISO 9001 audit success

6 April 2021 · Listed under Other News

Following an external audit, the NIHR Oxford Biomedical Research Centre (BRC) has again been successfully certified to the internationally recognised ISO 9001:2015 standard. The audit of the BRC’s funding Management System was carried out by the UKAS-accredited British Assessment ... READ MORE

Risk of severe COVID-19 from asthma and other respiratory diseases may be only modestly increased, new analysis suggests

1 April 2021 · Listed under COVID-19, Obesity, Diet and Lifestyle, Respiratory Medicine, Translational Data Science

An analysis of 8.3 million health care records in England shows that people with asthma have only a small increased risk of developing severe Covid-19. The study, led by University of Oxford researchers, examined routine patient data collected between January and April 2020 to generate risk ... READ MORE

Study analyses gender parity in Oxford BRC authorship

30 March 2021 · Listed under Other News

A study conducted by NIHR Oxford Biomedical Research Centre (BRC) researchers has shown that while there are positive trends in terms of the number of women authoring the BRC’s scientific papers, the proportion of female authors is significantly lower than male ones across all categories of ... READ MORE

Oxford researchers release cheap, quick COVID-19 antibody test

29 March 2021 · Listed under COVID-19, Inflammation across Tissues

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An international research team led by Oxford University scientists has developed a portable test for antibodies that fight the novel coronavirus that causes COVID-19. The test, which spots the presence of virus-fighting antibodies rather than a coronavirus infection, can be adapted to work on ... READ MORE

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