A new study has identified that NHS infant checks can miss serious hip abnormalities in new-born babies. Left undetected, these can require complex surgery, and lead to early arthritis. The study, published by the JAMA Network, was led by researchers at the University of Liverpool in ... READ MORE
Breakthrough aerosol human infection model gives hope for future TB vaccine development
University of Oxford researchers have for the first time established a controlled human infection model for tuberculosis (TB) that infects people via the lungs – the way TB enters the body. The clinical trial, which used the BCG vaccine delivered via aerosol into participants’ lungs, is a first ... READ MORE
Recipients of BRC doctoral funding present PhD projects
Six Oxford University Hospitals (OUH) nurses and allied health professionals who have received funding from NIHR Oxford Biomedical Research Centre (BRC) have presented their PhD projects to their fellow awardees and supervisors. The BRC provides up to £10,000 for the year to give the recipients ... READ MORE
New study reveals long-term mental health risks after COVID-19
A new study has shed light on the long-term mental health consequences of COVID-19 infection and the growing evidence of the protective effect of vaccination on reducing the risk. The research, supported by the NIHR Oxford Biomedical Research Centre (BRC), was conducted in a population-based ... READ MORE
Study assesses new MRI technique to detect liver cancer
Oxford researchers have been awarded funding to conduct a study comparing a new type of MRI (Magnetic resonance imaging) to standard of care ultrasound for liver cancer surveillance in people with cirrhosis. The University of Oxford’s DeLIVER team, which is investigating early detection methods ... READ MORE
Oxford BRC researcher named NIHR Senior Investigator
NIHR Oxford BRC researcher Professor Ronjon Chakraverty has received a prestigious national research award. Professor Chakraverty, Professor of Haematology in the Radcliffe Department of Medicine and Oxford BRC Co-theme Lead for Gene and Cell Therapy, was named a National Institute of Health ... READ MORE
COVID jab linked to lower risk of COVID-19-related clot and heart complications
The risk of cardiac and clot-related complications following COVID-19 is substantially reduced in people who receive the COVID-19 vaccination, compared with unvaccinated individuals, according to new research. The observational study, which was supported by the NIHR Oxford Biomedical Research ... READ MORE
Oxford wins funding to set up UK’s first registry of those at risk of type 1 diabetes
Oxford researchers have received funding to set up a UK registry for children and adults who are at risk of type 1 diabetes (T1D), by testing positive for diabetes autoantibodies. Diabetes autoantibodies are proteins that appear when the insulin-producing beta cells in the pancreas are damaged. ... READ MORE
NHS health checks can help to reduce disease rates and mortality, study finds
A University of Oxford study has found that attending an NHS Health Check is associated with a decreased risk of dying and of diseases, such as dementia, heart attack, kidney disease and liver cirrhosis. The results, published in BMC Medicine, suggest that preventative programmes such as ... READ MORE
Frozen shoulder holds key to understanding fibrosis resolution
Oxford researchers have identified how cells work to resolve frozen shoulder, opening up potential new targets for treatment and reducing the need for surgery. Frozen shoulder is a painful and disabling condition affecting the ligaments that form the shoulder joint capsule. Patients experience ... READ MORE
Race Inclusion talk explores improving diversity and inclusion in clinical trials
The NIHR Oxford Biomedical Research Centre (BRC) has sponsored a talk looking at how inclusion and diversity can be supported in clinical trials. The talk by Professor Mahendra Patel was organised a talk by Oxford University Hospitals BAME staff network as part of Race Inclusion ... READ MORE
BRC interns take first step on their research pathway
Eight Oxford University Hospitals (OUH) healthcare professionals have taken their first steps on the clinical academic pathway after presenting the results of their six-month NIHR Oxford Biomedical Research Centre (BRC) internship research projects. The internships are aimed at nurses, ... READ MORE
Evaluation hears benefits and challenges of citizen science project
A three-year NIHR Oxford Biomedical Research Centre (BRC) citizen science research study looking at treatments for non-alcoholic fatty liver disease (NAFLD) entered its final stages with a final visit from a European evaluation team. The study by the Oxford BRC and the Oxford Centre for ... READ MORE
Researchers cast the net widely for atrial fibrillation trial
An Oxford trial to detect atrial fibrillation has been designed to include as many eligible people as possible, including those who rarely interact with the healthcare system or take part in clinical trials. Working with 27 general practice surgeries, the AMALFI study, which is funded by the ... READ MORE
Study assesses long-term risk of invasive breast cancer after pre-invasive disease
A new study has provided evidence that women who have been diagnosed with ductal carcinoma in situ (DCIS) outside the NHS breast screening programme are around four times as likely to develop invasive breast cancer and to die from breast cancer than women in the general population. The study by ... READ MORE
Researchers develop easy-to-deploy federated learning system that safeguards patient data
Researchers in Oxford have developed a new, easy-to-use technique for hospitals to contribute to the development of artificial intelligence (AI) models, without patient data leaving the hospital’s premises. The technique, which builds on recent advances in decentralised machine learning, uses ... READ MORE
Trial studies inhalation of TB vaccine
A new clinical trial has been launched in Oxford to determine the effectiveness of delivering tuberculosis (TB) vaccines through inhalation. The study is being conducted by researchers at the University of Oxford’s Jenner Institute, who are giving BCG, the current licensed vaccine against ... READ MORE
Study highlights importance of ‘junk’ DNA in unlocking diagnosis
A new academic paper has revealed that areas of the human genome that are routinely overlooked in clinical tests may be the cause of some rare diseases. Assessing 122 patients with genetic conditions including rare forms of heart arrhythmia, brain inflammation, inflammatory bowel disease and ... READ MORE
New NIHR Oxford Senior Research Fellows named
Researchers from a wide range of disciplines have been appointed to be the next cohort of NIHR Oxford Senior Research Fellows – seven mid-career researchers identified as having the potential to become future translational research leaders. As in previous years, the selection ... READ MORE
Vaccine trial for deadly Nipah virus launched
The first participants have received doses of a new vaccine against Nipah virus in a clinical trial by University of Oxford researchers. Nipah virus is a devastating disease mostly found in South-East Asia that can be fatal in up to 75 percent of cases. This first-in-human trial of the vaccine ... READ MORE
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