New research by a team at the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre, provides a robust basis for informed shared decision-making and consent on keyhole knee surgery. An innovative study, published today in the Lancet, using 20 years’ worth of data covering ... READ MORE
Nitric Oxide conference gets under way in Oxford
Delegates from round the world have descended on Oxford for the 10th international conference of the Nitric Oxide Society, which has got under way. This year, the NIHR oxford Biomedical Research Centre is among the sponsors of the event. The conference, which is being held at the University of ... READ MORE
Research reveals link between high blood pressure and risk of aortic valve disease
New research has found that long-term exposure to high blood pressure is associated with an increased risk of aortic valve disease, with significant implications for clinical practice guidelines and health management. The findings, published in the European Heart Journal, are from a study of 5.4 ... READ MORE
Change at the helm of Oxford Biomedical Research Centre
The leading academic who has overseen the expansion of world-leading medical research at the NIHR Oxford Biomedical Research Centre (BRC) for the past nine years is stepping down. Professor Keith Channon will be replaced as Director of the Oxford BRC by Professor Helen McShane, a leading vaccine ... READ MORE
Study shows new technology can predict fatal heart attacks
Researchers at the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre (BRC), have developed a new technology based on analysis of computed tomography (CT) coronary angiograms that can identify patients at risk of deadly heart attacks years before they occur. Heart ... READ MORE
Lifestyle factors linked to brain health of young adults
Researchers at Oxford’s John Radcliffe Hospital have used advanced magnetic resonance imaging (MRI) to investigate whether factors such as blood pressure, fitness, smoking and alcohol intake during young adult life are associated with changes in the blood vessels inside the brain. The University ... READ MORE
Study looks at why co-amoxiclav-resistant E coli infections are on the rise
A study looking at health records in Oxfordshire over nearly 20 years has suggested that measures to improve antibiotic use in GP surgeries might help to combat the spread of difficult-to-treat, antibiotic-resistant E coli infections. The study, published in the Lancet Infectious Diseases, found ... READ MORE
Genetic link discovered between circadian rhythms and mood disorders
In the largest ever genetic study of circadian rest-activity cycles in humans, scientists at the University of Glasgow, supported by data from the NIHR oxford Biomedical Research Centre (BRC), have identified a possible genetic link between circadian disruption and mood disorders. The new ... READ MORE
Oxford researcher gets additional prize for his research into immunology of asthma
A University of Oxford researcher has been awarded a top scientific prize to add to a prestigious fellowship he was given in June. Dr Tim Hinks was awarded the £25,000 Wellcome-Beit Prize for his research into the immunology of lung diseases, including asthma. The prize is given to four ... READ MORE
New research on recovery following intensive care treatment
Out-of-hours discharge from intensive care is strongly associated with both in-hospital death and ICU readmission, according to a study supported by the NIHR Oxford Biomedical Research Centre. The systematic review and meta-analysis by researchers from the University of Oxford’s Nuffield ... READ MORE
Fourth digital health product developed as part of Sensyne agreement
A software product that underpins a remote management service for patients with heart failure has been licensed by the UK digital health company Sensyne Health as part of a strategic research agreement with the University of Oxford and Oxford University Hospitals (OUH) NHS Foundation ... READ MORE
Stem cell transplants to be used in treating Crohn’s disease
A new clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn’s disease. Oxford University Hospitals NHS Foundation Trust is one of the centres where the trial will be conducted, and where patients will be recruited. Research at ... READ MORE
Controlling infection essential to tackle global anaemia
A study supported by the NIHR Oxford Biomedical Research Centre has concluded that iron supplements on their own are not enough to efficiently tackle anaemia in places with high infection burdens. In a paper published in The BMJ, Prof Hal Drakesmith from the MRC Human Immunology Unit, based at ... READ MORE
Students go in2science to get invaluable lab experience
Six A-level students have been getting first-hand experience of working in a top research laboratory during their summer holidays. The students, from different schools across Oxfordshire, have been getting valuable work experience at the Oxford Centre for Diabetes, Endocrinology and Metabolism ... READ MORE
First treatment designed specifically to prevent migraine gets European licence
The first ever drug specifically designed to prevent migraines in adults has been approved by the European Medicines Agency (EMA), and the head of the Oxford Headache Centre has said the news represents a new approach in treating the condition. The EMA granted a licence for the use of erenumab, ... READ MORE
Knowing you are pre-diabetic does not usually lead to changes in lifestyle, study finds
Social and cultural factors mean that people who are told they are pre-diabetic are too often unable to make the necessary lifestyle changes to prevent progression to diabetes, according to a study by researchers supported by the NIHR oxford Biomedical Research Centre. The study, ‘How are ... READ MORE
Researchers map leukaemia ‘family trees’ in patients treated with new drug
A team of international researchers, including experts from NIHR Oxford BRC, has for the first time mapped the family trees of cancer cells in acute myeloid leukaemia (AML) to understand how this blood cancer responds to a new drug, enasidenib. The work also explains what happens when a patient ... READ MORE
Pregnant women invited to take part in pioneering diabetes prevention research
Pregnant women are being invited by the University of Oxford and the NHS to take part in the world’s first clinical trial to prevent type 1 diabetes in babies and infants. Researchers supported by the NIHR Oxford Biomedical Research Centre want to find out if giving small amounts of insulin to ... READ MORE
Ultrasound and nanomedicine offer new hope for improving effects of cancer drugs
In a breakthrough that allows the more precise targeting of drugs at cancers, a University of Oxford team has used ultrasound and lipid drug carriers to remotely trigger and enhance the delivery of a cancer drug in humans for the first time. The study was conducted by researchers from the ... READ MORE
Oxford Impact 2018 workshop
Last month, the NIHR Oxford BRC and the UK Cochrane Collaboration organised the Oxford Impact 2018 workshop, which brought together people from a wide range of fields to “think differently about research impact”. The event sought to tackle one of the central challenges of what has become known as ... READ MORE
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