Professor Robert MacLaren from the University of Oxford and Professor Miguel Seabra from Imperial College London are undertaking a clinical trial using gene therapy to treat a disease that causes blindness known as choroideraemia. This condition is currently incurable and affects thousands of people ... READ MORE
Trial to investigate new drug combination in lung cancer
Cancer Research UK’s Drug Development Office has opened the first trial of a new drug combination in patients with advanced solid tumours and in a subset of patients who have non-small cell lung cancer. This trial will combine two compounds that aim to starve the tumours while simultaneously ... READ MORE
Oxford researchers elected to the Academy of Medical Sciences
Two medical researchers from the Oxford University Hospitals NHS Trust and the University of Oxford have been elected as Fellows of the Academy of Medical Sciences. Professors Tipu Aziz and Rury Holman are among the 46 new Fellows announced by the Academy for their outstanding contributions to ... READ MORE
First electronic retina implanted in the UK
Surgeons in Oxford are the first in the UK to successfully implant an electronic retina into the back of an eye. On 22 March 2012, Chris James became the first patient in the UK to receive this ground-breaking surgery as part of a clinical trial being carried out at John Radcliffe Hospital and ... READ MORE
Professor Russell Foster wins Social Innovator award
Russell Foster (left), Professor of Circadian Neuroscience and Head of the Department of Ophthalmology at the University of Oxford, has been awarded the Social Innovator prize, by the Biotechnology and Biological Sciences Research Council (BBSRC), for his work to revolutionise our understanding of ... READ MORE
Can daily aspirin help prevent and treat cancer?
A collection of three papers (two published in The Lancet and one in The Lancet Oncology) add to the growing evidence base suggesting that daily aspirin can be used to help prevent and possibly treat cancer. All three papers are by Professor Peter Rothwell, University of Oxford and John Radcliffe ... READ MORE
Hundreds get hands-on at the Churchill
Hundreds of visitors found themselves getting hands-on at the third research open day at the Churchill Hospital on 14th March. As part of the Oxford Biomedical Research Centre’s ongoing commitment to involve and engage the public in the research carried out in Oxford hospitals, the open day was ... READ MORE
Research@Oxford – Improving Health
On 14th March 2012 the NIHR Biomedical Research Centre and the Oxford Cancer Research Centre (right) hosted a public open day on research that is designed to improve health. A morning session was held for secondary schools, introducing them to the world of cancer research. Scientists, doctors, ... READ MORE
Study looks at research nurses’ career and support needs
In early February more than 100 delegates filled the reception rooms at Headington Hill Hall to hear Professor Mary Boulton talk about her recent research into the experiences of research nurses employed by the Oxford Biomedical Research Centre (OxBRC). The research was funded by Thames Valley HIEC ... READ MORE
Students inspired by visit to OCDEM
On March 8th, Oxford Centre for Diabetes Endocrinology & Metabolism (OCDEM) and the NIHR Biomedical Research Centre, Oxford hosted a visit for sixth form students from King Alfred School, Wantage. The students met some of the OCDEM researchers including Professor Keith Frayn, who explored the ... READ MORE
Genetic changes tracked as bacteria become a fatal infection
An unusual case could tell researchers more about the genetic changes that occur when a common bacteria, normally carried without any problems, on rare occasions causes potentially life-threatening infections. Eight mutations occurred in the common bacteria Staphylococcus aureus as it turned from ... READ MORE
More funding for groundbreaking research in Oxford
£3.7 million, over five years, has been awarded to Oxford University Hospitals NHS Trust for facilities that will carry out research in areas such as communication impairments in children, social anxiety disorder, post traumatic stress disorder, depression, schizophrenia, and stroke. The bid for ... READ MORE
Oxford research sheds new light on Clostridium difficile infection in hospitals
It has been a widely held belief that most C. difficile infections are spread in hospital from a case with active disease to other patients. A recent study, funded by the National Institute of Health Research, in Oxford and Leeds however shows that the vast majority of C. difficile cases in ... READ MORE
How has the pneumococcus bacteria evolved after the introduction of a childhood vaccine?
Researchers from the University of Oxford and the US Centers for Disease Control and Prevention (CDC) used the latest DNA sequencing techniques to investigate how pneumococcus bacteria evolved after the introduction of a childhood vaccine in 2000 in the USA. Streptococcus pneumoniae infections ... READ MORE
Study seeks people with memory loss
Research study (SCarlet RoAD) opens to test an investigational medication for the treatment of prodromal Alzheimer’s disease On 20 January 2012 the OPTIMA Project (Oxford Project to Investigate Memory and Ageing: Nuffield Department of Medicine, University of Oxford) based at the John Radcliffe ... READ MORE
First trial of a new hepatitis C vaccine shows promise
A new vaccine against the chronic liver disease hepatitis C has shown promising results in a first clinical trial in humans, Oxford University researchers report. The vaccine, based on a modified cold virus, generated immune responses similar to those seen in the minority of people who are ... READ MORE
New Year’s Honour for Professor of Biomedical Engineering
Professor Lionel Tarassenko, of the Department of Engineering Science and St John’s College, and director of the Institute for Biomedical Engineering, was made a CBE for services to engineering. He holds the Chair of Electrical Engineering. His research is focused on the development of signal ... READ MORE
Treating sleep problems may be important in schizophrenia
A study of schizophrenia patients has found profound disruptions in their sleep patterns, with half also having irregular body clocks that are out of synch with the pattern of night and day. The Oxford researchers argue that the extent and severe nature of these long-term sleep problems should be ... READ MORE
Stroke feature: restructuring the brain
A Wellcome Trust article highlights the work of Professor Heidi Johansen-Berg at the University of Oxford and her research exploring the structural changes in the brain’s white and grey matter that underlie learning. Understanding the precise cellular nature of those changes may improve diagnosis of ... READ MORE
Oxford University Hospitals rated in top 5 for research activity
Oxford University Hospitals NHS Trust is one of the top Trusts leading the way in providing opportunities for patients to take part in clinical research studies. Highlighted in a league table1 published for the first time by the National Institute for Health Research (NIHR) Clinical Research ... READ MORE
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