First patient recruited for key drug treatment trial
A clinical trial to test whether Azithromycin, a commonly used antibiotic, can treat the symptoms of COVID-19 in outpatients has recruited its first patient. The ATOMIC2 trial, which is being led from Oxford, will enrol 800 people who are being assessed at hospital with COVID-19 but felt well enough to be cared for at home. … Read more
Oxford Blood Group: Exchange Newsletter Issue 3 vol 1 / June 2019
Summary of the Crohn’s & Colitis Open Evening
On Thursday 7th February 2019, over 170 members of the public affected by Crohn’s Disease or Ulcerative Colitis attended a ‘Crohn’s and Colitis Open Evening’ at the John Radcliffe Hospital, Oxford. Below is a PDF summary of the event plus a slideshow with slides from the Powerpoint presentation given at the Open Evening.
Genetic changes associated with physical activity emerge thanks to machine learning pioneers
Time spent sitting, sleeping and moving is determined in part by our genes, University of Oxford researchers have shown. In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on their wrist for a week. The scientists taught … Read more
Oxford Blood Group: Exchange Newsletter Issue 1 vol 2 / Nov 2018
Public invited to help tackle antibiotic resistance
An online project has been launched to study antibiotic resistance in Tuberculosis (TB) with the help of the public. The project website, bashthebug.net, shows volunteers images of a series of small, circular wells, each containing M.tuberculosis (the bug that causes TB) and a different dose of an antibiotic. The users are then asked to identify … Read more
Five more years of transforming care through research
An exciting new chapter in NHS medical research in Oxford begins today (April 1) with the £113.7m renewal of the NIHR Oxford Biomedical Research Centre (BRC). The BRC is a partnership between Oxford University Hospitals NHS Foundation Trust and the University of Oxford to fund medical research that can transform NHS care. The BRC was … Read more
England world leaders in the use of Whole Genome Sequencing to diagnose TB
In a world-first, Whole Genome Sequencing (WGS) is now being used to identify different strains of tuberculosis, announced Public Health England today. This is the first time that WGS has been used as a diagnostic solution for managing a disease on this scale anywhere in the world. This builds on WGS based services for public … Read more
New trial for blindness rewrites the genetic code
Researchers have started a new gene therapy clinical trial to treat X-linked retinitis pigmentosa (XLRP), the most common cause of blindness in young people. Retinitis pigmentosa is currently untreatable and leads to a slow and irreversible loss of vision. On 16 March 2017, a 29-year-old British man became the first patient with X-linked retinitis pigmentosa … Read more
Genetic sequencing offers same-day TB testing
Researchers have for the first time shown that standard tuberculosis (TB) diagnostic tests can be replaced by a sub-24 hour genetic test applied to the TB bacteria in a patient’s sputum. It currently takes up to two months to obtain the full diagnostic information for a patient with TB, as the bacteria grow very slowly … Read more
Hospital tablet computers cut nurse time by up to 30 per cent, study finds
A project to replace bedside paper charts with tablet computers in Oxfordshire’s NHS hospitals reduced the typical time taken to input patients’ vital signs by up to 30%, a study has found. The System for Electronic Notification and Documentation (SEND) was developed by the University of Oxford for recording patient vital signs. A study of … Read more
Public Health Minister Visits Oxford Cancer Hospital ahead of World Cancer Day
Ahead of World Cancer Day on February, Public Health Minister Nicola Blackwood highlighted the importance of UK scientific research to beating cancer during a visit to the Churchill Hospital. The Public Health and Innovation Minister saw state-of-the-art clinical trials and facilities for new cancer treatments and patients, both supported by the NIHR Oxford Biomedical Research … Read more
Oxfordshire research funding programme praised for impact on NHS
A 10-year programme of research funding at Oxfordshire’s hospitals has had a positive impact on patient care, a new paper has reported. Interviews with clinical leaders on the work of the NIHR Oxford Biomedical Research Centre (BRC) found ‘numerous’ examples of positive impact on patient care. The interviews with 37 leaders also identified challenges resulting … Read more
Industry partnership to deploy digital technology in NHS
Drayson Technologies, Oxford University and Oxford University Hospitals (OUH) NHS Foundation Trust have signed three agreements to collaborate on the development, testing and future commercialisation of three clinically validated digital health products arising from BRC-funded research undertaken by engineers and doctors at Oxford University and OUH. The products are designed to provide significant improvements in … Read more
Antibiotics, not dirty hospitals, the main cause of C. difficile epidemic
Restricting the use of a common antibiotic was more important than a high profile “deep clean” of hospitals in massively reducing UK antibiotic resistant Clostridium difficile (C. diff) cases, a major new study has found. The study concluded that overuse of antibiotics like ciprofloxacin led to the outbreak of severe diarrhoea caused by C. difficile … Read more
Second key step for eye robot trial
A robot has been used to inject a drug into the back of the eye in a world first for the next phase of a landmark clinical trial at Oxford’s John Radcliffe Hospital. Prof Robert MacLaren used the remotely controlled robot to administer a tiny volume of blood dissolving agent tPA under the retina to … Read more
Funding boost for genetics centre
A major University of Oxford genetics research centre that supports Oxford BRC research is to share £118m of new funding. Global medical research funding charity Wellcome has announced funding for The Wellcome Centre for Human Genetics. The aim of the centre is to advance understanding of health and disease, and span fundamental and social sciences, … Read more
Nanopore genetics breakthrough supported by Oxford BRC
Oxford University’s Wellcome Trust Centre for Human Genetics (WTCHG) and the leading genome analytics company Genomics plc has announced the first sequencing and analysis of multiple human genomes using nanopore technology. The announcement, made on Thursday, December 1, at the Oxford Nanopore Community Meeting in New York City, marks a major breakthrough in sequencing technology … Read more
Tower turns blue for diabetes awareness
Churchill Hospital staff lit Oxford’s Magdalen Tower blue and hosted a research open day to spread awareness about diabetes. Staff from The Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) arranged for the iconic landmark to be lit to mark World Diabetes Day on November 14, a first for the city. Each year, buildings around … Read more
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