With drug-resistant strains of sexually-transmitted infection gonorrhoeae increasing, scientists from Brighton, Oxford University and Public Health England have found that genetic sequencing can track the spread of infection. They show coordinated national and international strategies are required to stop drug-resistance spreading further. Their study, funded by the NIHR Oxford Biomedical Research Centre (BRC) and the NIHR Healthcare-Associated … Read more
Genetics of type 2 diabetes revealed in unprecedented detail
The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition. More than 300 scientists from 22 countries collaborated on the study, which analysed the genomes of more than 120,000 people with ancestral origins in Europe, South and East Asia, the Americas … Read more
BRC researcher honoured for Africa radio project
A researcher supported by the NIHR Oxford Biomedical Researcher has been recognised by the University of Oxford for work to communicate with children in Africa about the Ebola outbreak. Dr Matthew Snape was one of 12 winners in the inaugural Vice-Chancellor’s Awards for Public Engagement with Research. Dr Snape, of the University’s Oxford Vaccine Group, … Read more
Data debate video and podcast now online
A video of an hour-long debate on issues around mass sharing of patient data to support research and improve patient care can now be viewed online. “Good to share? Data, research, privacy and the NHS” was held as part of the NIHR Oxford Biomedical Research Centre’s Public Open Day – Celebrating Biomedical Research on April … Read more
Researchers find more uses for immune system’s ‘Swiss army knife’
Oxford University research supported by the NIHR Oxford Biomedical Research Centre has found that a little-studied and relatively unknown part of the human immune system could be twice as important as previously thought. Mucosal Associated Invariant T-cells (MAIT cells) were first identified in 1993 but largely ignored until recently. Australian researchers recently found that they … Read more
Audit success for BRC
The NIHR Oxford Biomedical Research Centre’s funding Management System is certified to the Internationally recognised standard ISO 9001:2008. In March 2016 the BRC operations team successfully participated in an external Audit by ACS Registrars Ltd (a UKAS Accredited Certification Body). The successful audit of the ISO 9001:2008 standard confirms that excellent Quality Management Systems are … Read more
High blood pressure linked to vascular dementia
High blood pressure could significantly raise the risk of developing the second most common form of dementia, according to a new study from The George Institute for Global Health. The medical records of more than four million people were analysed with researchers finding heightened blood pressure was associated with a 62 per cent higher risk … Read more
Immediate aspirin after mini-stroke substantially reduces risk of major stroke
Using aspirin urgently could substantially reduce the risk of major strokes in patients who have minor ‘warning’ events, a group of European researchers has found. Writing in the Lancet, the team say that immediate self-treatment when patients experience stroke-like symptoms would considerably reduce the risk of major stroke over the next few days. Aspirin is … Read more
Heart warning over “fight or flight” tumour
A rare tumour that randomly secretes stress hormones – historically leading some doctors to diagnose sufferers with a psychiatric disorder – does more damage to the heart than previously thought, University of Oxford research reports today. In the largest study of its kind, researchers said phaeochromocytoma tumours in the adrenal glands, which sit above the … Read more
Statin treatment before heart surgery does not prevent heart damage or atrial fibrillation
Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and co-funded by the NIHR Oxford Biomedical Research Centre. The trial, which is the largest of … Read more
“Bionic eye” to feature on ITV documentary
The story of a patient who was among the first in the UK to receive the world’s most advanced ‘bionic eye’ is to feature on ITV this month. Nikki Watson’s story will feature on “What Would Be Your Miracle?” on ITV 1 on Thursday, May 12 at 9pm. The 48-year-old, from Devon, was diagnosed with … Read more
Gene therapy shows long-term benefit for treating rare blindness
Pioneering gene therapy has restored some vision to patients with a rare form of genetic blindness for as long as four years, raising hopes it could be used to cure common causes of vision loss, new University of Oxford research published today shows. A technique which involves injecting a virus into the eye to deliver … Read more
Study examines factors affecting whether women choose a medical research career
Unless exposed to positive research experience and role models during their medical education and training, women are unlikely to consider careers in academic medicine seriously. That’s one conclusion of an Oxford University study supported by the NIHR Oxford Biomedical Research Centre published in The Lancet. It asked why, when entry to medical schools is evenly … Read more
Hundreds enjoy BRC open day
Hundreds of people visited an open day at the John Radcliffe Hospital about biomedical research taking place in Oxford. The event showcased the work of the NIHR Oxford Biomedical Research Centre (BRC), a partnership between the Trust and University of Oxford to fund and support research that can benefit the NHS. It included more than … Read more
Researchers target intensive care’s intensive noise problem
Researchers have been working with patients to study how to reduce noise in the intensive care unit (ICU) at the John Radcliffe Hospital. Television presents one picture of an intensive care unit – dimmed lights, hushed voices and softly bleeping machines. The reality is that it’s more like a busy restaurant and frequently it’s noisy … Read more
New tool to improve blood pressure measurement
Scientists at Oxford University have developed a new way of estimating our true underlying blood pressure that overcomes common problems in a clinical setting which can lead to misleading results. Blood pressure measurement is frequently used by medics to understand our health, and dangerously high blood pressure (hypertension) can lead to serious conditions like heart … Read more
Electrical brain stimulation could support stroke recovery
Applying an electric current to the brain can help recovery from stroke, Oxford University researchers at the John Radcliffe Hospital have found. A team from Oxford’s Nuffield Department of Clinical Neurosciences, led by Professor Heidi Johansen-Berg and Dr Charlotte Stagg, studied the use of transcranial direct current stimulation (tDCS) to support rehabilitation training. The technique … Read more
Inspiring Open Day on medical research by the NIHR Oxford Biomedical Research Centre
A public open day to showcase groundbreaking medical research that is taking place in Oxford across a range of conditions such as cancer and diabetes will be held at the John Radcliffe Hospital (JR) next month. Talks, a tour of clinical facilities, stalls and a debate about the opportunities and challenges of sharing patient data … Read more
Get inside your own head during brain week
How do we perceive pain? How does light affect out mood? Can sound affect the taste of food? Do genes make some people more sociable? All these questions – and more – will be answered during Oxford’s Brain Awareness Week, running from 14 – 20 March. A series of interactive activities and public lectures will … Read more
Prostate cancer vaccine trial seeks volunteers
Oxford University scientists have started a clinical trial to test a new vaccine against prostate cancer and are looking for volunteers to take part. The first four participants have already received this experimental vaccine at the Churchill Hospital in Oxford, and the second trial site has just been opened at the Royal Hallamshire Hospital in … Read more
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