A new consortium of 27 international partners from academia, industry, and small and medium enterprises, aims to tackle the unmet challenge of discovery and characterisation of blood-brain barrier targets and transport mechanisms for brain delivery of therapeutics to treat neurodegenerative ... READ MORE
Study suggests immune system plays key role in survival after pancreatic cancer surgery
Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells - may play an important role in survival after surgery to remove pancreatic cancer. The study by the University of Oxford’s Department of Oncology and Kennedy ... READ MORE
Oxford researchers develop new technique to analyse cancer cells’ life history
A team of researchers from the University of Oxford has developed a new technique that allows scientists to reliably track genetic errors in individual cancer cells, and find out how these might lead to uncontrollable growth. The research by the MRC Weatherall Institute of Molecular Medicine, ... READ MORE
Researchers worried that people with chronic disease are not active enough
A study of over 96,000 men and women in the UK, with an average age of 64.5 years, has found that those with chronic conditions are spending considerably less time on physical activity than their healthy peers, and so are missing out on its health management benefits. The ... READ MORE
Pills as good as injections to treat bone and joint infections, paper finds
Pills are just as effective as intravenous (IV) injections in tackling bone infections, a study led by Oxford-based researchers has found. The findings, published on 30 January in The New England Journal of Medicine, challenge the long-held belief that injections into the vein are the best way ... READ MORE
Largest-ever clinical trial in hip fracture fixation reaches key milestone
A randomised controlled trial comparing extracapsular hip fracture fixation devices, conducted by Oxford University and supported by NIHR Oxford Biomedical Research Centre, has reached a key milestone, with the 1000th patient recruited completing their one-year follow-up Recruitment for the ... READ MORE
Does general practice get a bad press?
Newspaper articles in the UK about general practice are currently very negative, and efforts should be stepped up to influence the media to provide a more balanced perspective, according to an Oxford BRC-supported study. The study by Eleanor Barry and Prof Trish Greenhalgh, of the University of ... READ MORE
BRC Theme Lead Richard Hobbs appointed CBE
Professor Richard Hobbs, the NIHR Oxford BRC’s Theme Lead for Multimorbidity and Long-term Conditions, has been appointed a CBE in the 2019 New Year's Honours for his services to medical research. Prof Hobbs, a practising inner-city GP for over 38 years, is Head of the University of Oxford’s ... READ MORE
Concerns raised as opioid prescriptions rise across UK
Researchers supported by the NIHR Oxford Biomedical Research Centre(BRC) have recommended greater action to promote best practice, as a new study revealed a rise in prescriptions of opioids for treating chronic pain over thepast 20 years. The research reviewing opioid prescribing, published in ... READ MORE
Genetic changes associated with physical activity emerge thanks to machine learning pioneers
Time spent sitting, sleeping and moving is determined in part by our genes, University of Oxford researchers have shown. In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on ... READ MORE
BRC-supported symposium builds engagement platform for research impact assessment
An international symposium, jointly organised by the NIHR Oxford BRC, –has brought together delegates from around the world to discuss how to maximise the impact of medical research. Some 87 delegates from eight countries assembled at Jesus College in Oxford on 16 November for the interactive ... READ MORE
Oxford Blood Group: Exchange Newsletter Issue 1 vol 2 / Nov 2018
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Over half of former ICU patients report symptoms of psychological disorders
Patients in the UK who have survived critical illnesses requiring care in an intensive care unit (ICU) frequently report symptoms of anxiety, PTSD and/or depression. Researchers at the University of Oxford investigated psychological disorders in a cohort of 4,943 former ICU patients. They found ... READ MORE
Prof Duncan Richards appointed to key new Clinical Therapeutics role
A newly appointed professor at the University of Oxford’s Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) will lead Oxford’s answer to the key global challenge of how to determine quickly which potential new therapies have the properties to become important ... READ MORE
Schoolchildren and researchers gather to mark World Diabetes Day
Local schoolchildren joined University of Oxford researchers and diabetes patients to mark World Diabetes Day on Wednesday, but forming a blue circle around the famous Triton statue in the Radcliffe Observatory quarter. The awareness-raising event was organised by the NIHR Oxford Biomedical ... READ MORE
Oxford secures £17.5 million to lead national programmes in AI to improve healthcare
Medical research teams in Oxford will benefit from £17.5 million in new funding thanks to a government initiative to boost new artificial intelligence (AI) healthcare projects that benefit patients with a range of conditions. Funding will be provided to the University of Oxford through the ... READ MORE
New clinical tool will help patients with acute ankle sprain
Patients arriving at hospital emergency departments with acute ankle sprains can expect more timely advice and follow-up care in future after researchers in Oxford developed a new tool that will aid clinical decisions on treatment. Ankle sprains are very common and represent up to 5 per cent of ... READ MORE
Gestational diabetes app officially launched
A smartphone application for women with gestational diabetes, developed with support from NIHR Oxford Biomedical Research Centre, has been launched commercially. GDm-Health has now completed its development following a two-year clinical evaluation in the NHS by over 1,000 women, and is currently ... READ MORE
Study reveals trends in incidence of spontaneous pneumothorax
Oxford researchers supported by the NIHR Oxford Biomedical Research Centre have published research that show how the rates of incidence and recurrence of spontaneous pneumothorax have changed over time. The research, published on 9 October in the Journal of the American Medical Association, ... READ MORE
Gene therapy breakthrough in treating rare form of blindness
The world’s first gene therapy trial for a genetic cause of blindness known as choroideremia has shown positive results. The trial, supported by NIHR Oxford Biomedical Research Centre (BRC), began in 2011 at the Oxford Eye Hospital, part of the Oxford University Hospitals NHS Foundation ... READ MORE
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