The first ever drug specifically designed to prevent migraines in adults has been approved by the European Medicines Agency (EMA), and the head of the Oxford Headache Centre has said the news represents a new approach in treating the condition. The EMA granted a licence for the use of erenumab, ... READ MORE
Knowing you are pre-diabetic does not usually lead to changes in lifestyle, study finds
Social and cultural factors mean that people who are told they are pre-diabetic are too often unable to make the necessary lifestyle changes to prevent progression to diabetes, according to a study by researchers supported by the NIHR oxford Biomedical Research Centre. The study, ‘How are ... READ MORE
Researchers map leukaemia ‘family trees’ in patients treated with new drug
A team of international researchers, including experts from NIHR Oxford BRC, has for the first time mapped the family trees of cancer cells in acute myeloid leukaemia (AML) to understand how this blood cancer responds to a new drug, enasidenib. The work also explains what happens when a patient ... READ MORE
One dose of aspirin doesn’t fit all
About one billion people worldwide take regular aspirin, usually to prevent heart attacks or strokes. Writing in The Lancet, researchers have shown that ‘one-dose-fits-all’ use of aspirin to prevent heart attacks, stroke or cancer, is ineffective or harmful in the majority of people, and that a ... READ MORE
Pregnant women invited to take part in pioneering diabetes prevention research
Pregnant women are being invited by the University of Oxford and the NHS to take part in the world’s first clinical trial to prevent type 1 diabetes in babies and infants. Researchers supported by the NIHR Oxford Biomedical Research Centre want to find out if giving small amounts of insulin to ... READ MORE
Ultrasound and nanomedicine offer new hope for improving effects of cancer drugs
In a breakthrough that allows the more precise targeting of drugs at cancers, a University of Oxford team has used ultrasound and lipid drug carriers to remotely trigger and enhance the delivery of a cancer drug in humans for the first time. The study was conducted by researchers from the ... READ MORE
#OxfordImpact2018
Post by Prof Trish Greenhalgh, NIHR Oxford BRC Theme Lead for Partnerships for Health, Wealth and Innovation The most memorable sentence from this one-day workshop held at Jesus College, Oxford, on 21 June 2018 was from keynote speaker Mark Taylor. Reflecting on his experience as a patient with ... READ MORE
Oxford Impact 2018 workshop
Last month, the NIHR Oxford BRC and the UK Cochrane Collaboration organised the Oxford Impact 2018 workshop, which brought together people from a wide range of fields to “think differently about research impact”. The event sought to tackle one of the central challenges of what has become known as ... READ MORE
More awareness needed about stroke risk after mini-stroke, study finds
A leading Oxford stroke specialist says more needs to be done to raise of awareness of the need to take rapid action after a mini-stroke in order to reduce the number of major strokes. The study of more than 2,200 patients across Oxfordshire was led by Prof Peter Rothwell (right), of the Nuffield ... READ MORE
BRC visited by senior DHSC figure
The Department of Health and Social Care’s Chief Scientific Adviser, Prof Chris Whitty, visited Oxford on Monday 2nd July to find out about the world-leading research taking place there and to meet young medical researchers starting out on their career. After a meeting at the John Radcliffe ... READ MORE
Study launched to investigate link between sleep problems and Parkinson’s
Researchers in the Oxford Parkinson’s Disease Centre have launched a new five-year study looking at the links between a condition known as Rapid Eye Movement Sleep Behaviour Disorder (RBD) and Parkinson’s. Supported by the NIHR Oxford Biomedical Research Centre, the study seeks to improve the ... READ MORE
Oxford gets government funding to expand antimicrobial resistance work
Researchers in Oxford have been awarded £1.8m in capital funding from the Department of Health and Social Care to expand their work to tackle the growing problem of antimicrobial resistance (AMR), including using whole genome sequencing to diagnose AMR. The funding was awarded to the NIHR ... READ MORE
All newborns with Down’s syndrome to get leukaemia test under new guidelines
New national guidelines are recommending that all babies born with Down’s syndrome should have a new genetic test to detect signs of a potentially fatal preleukaemic condition, following research by a University of Oxford group led by NIHR Oxford BRC-supported investigators. The new British ... READ MORE
First human test of robotic eye surgery a success
The first trial of robot-assisted eye surgery in patients has shown the technique to be both safe and effective. Researchers from the University of Oxford, supported by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC) have completed the first successful ... READ MORE
Therapeutics and collaboration in the spotlight at Technology Showcase
This year’s Technology Showcase, held on 13 June at Oxford’s Saïd Business School, attracted a host of leading academics, clinicians and investors to discuss the most exciting commercial opportunities and projects in the field of Therapeutics, Small Molecules and Biologics. The event, which was ... READ MORE
Oxford researcher gets £1m boost to study immunology of asthma
A University of Oxford researcher has received a £1m grant to expand his research into the immunology of lung diseases, including asthma. Dr Tim Hinks has been awarded a Wellcome Trust Clinical Research Career Development Fellowship. The funding that comes with the award will allow Dr Hinks, who ... READ MORE
Type 2 diabetes linked to higher rate of Parkinson’s
People with type 2 diabetes are 32% more likely to develop Parkinson’s disease than those without diabetes, a new study by UCL, University of Oxford and Queen Mary University of London researchers has found. The research, published today in Neurology, the medical journal of the American Academy ... READ MORE
Supermarket interventions could play role in public health strategies, study finds
Oxford researchers have found that interventions carried out in in grocery stores - such as manipulating price or availability or suggesting swaps – have an impact on purchasing and could play a role in public health strategies to improve the nutritional quality of people’s diets. The study, ... READ MORE
New haematology patient group launched
The launch of a new patient engagement group for those with blood conditions has brought together patients, clinicians and researchers to discuss how to get patient involved in research. A screening of the film People are Messy at the Ultimate Picture Palace followed by a group discussion ... READ MORE
Health minister visits Oxford BRC
The Health Minister, Lord O'Shaughnessy, visited the NIHR Oxford BRC on Wednesday 30 May to take a look at the ground-breaking research that is taking place in the fields of cancer and genomics. He was accompanied on the tour by Oxford BRC Director Prof Keith Channon and Head of Research ... READ MORE
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