A study led by Oxford researchers has identified 28 percent more cases of atrial fibrillation, a common and serious cardiac condition, in primary care data than secondary care data alone. Evidence of atrial fibrillation was also recorded an average of 1.3 years earlier. The findings - published ... READ MORE
Scientists create new way to predict bowel cancer risk in people with IBD
Researchers have found a way to identify people with inflammatory bowel disease (IBD) who are at the highest risk of developing bowel cancer. IBD, which affects around 500,000 people in the UK, includes ulcerative colitis and Crohn’s disease. They irritate the lining of the bowel, which can ... READ MORE
Oxford and GSK launch £50million programme to advance novel cancer research
Leading NIHR Oxford Biomedical Research Centre researchers will play a key role in a major new collaboration between the University of Oxford and global biopharma company GSK to advance the understanding of how cancer develops, which could inform future development of vaccines to prevent ... READ MORE
BRC-supported rheumatologist receives prestigious NIHR professorship
An Oxford BRC-supported researcher has become the first rheumatologist to be awarded a prestigious Research Professorship from the National Institute for Health and Care Research (NIHR). Professor Laura Coates (pictured), a Senior Clinical Research Fellow in the Nuffield Department of ... READ MORE
Blood test developed to allow early detection of multiple cancers
Researchers at the University of Oxford have unveiled a new blood test – powered by machine learning – which shows real promise in detecting multiple types of cancer in their earliest stages, when the disease is hardest to detect. Named TriOx, this innovative liquid biopsy test analyses ... READ MORE
Oxford to play key role in two new MRC gene therapy centres
The Medical Research Council (MRC), part of UKRI, is launching its first two Centres of Research Excellence (CoRE), which will develop transformative new advanced therapeutics for currently untreatable diseases. Oxford is leading one of these centres and co-leading the other. Together, these ... READ MORE
Collaboration evaluates new drug for treatment of autonomous cortisol secretion
Scientists from the Universities of Oxford and Sheffield are collaborating with the US biopharmaceutical company Sparrow Pharmaceuticals on DC-MACS a Phase 2 clinical study of the drug clofutriben to treat autonomous cortisol secretion (ACS). Clofutriben, also known as SPI-62, is produced by ... READ MORE
Wearable devices can help predict five-year risk of falls for people with Parkinson’s
University of Oxford researchers have demonstrated how clinicians could use data to predict the risk of falls in people with Parkinson’s disease (PD) to help improve effective longer-term care planning. Falls are a common problem for people living with Parkinson’s. A recent review estimated ... READ MORE
Machine learning outperforms surgeons in predicting knee replacement outcomes
A new study has revealed that machine learning models can significantly outperform experienced surgeons in predicting patient outcomes after partial knee replacement. Unicompartmental (partial) knee replacement (UKR) is a common procedure designed to relieve pain in patients with knee ... READ MORE
Oxford professor named among world’s top 100 ophthalmologists
The Oxford BRC’s Theme Lead for Gene and Cell Therapy, Professor Robert MacLaren, has been ranked in the top 100 ophthalmologists worldwide for 2024 by the international Ophthalmologist magazine. The ranking was based on votes from key leaders across ophthalmology, academia and ... READ MORE
First new treatment for asthma attacks in 50 years
An injection given during some asthma and chronic obstructive pulmonary disease (COPD) attacks is more effective than the current treatment of steroid tablets, reducing the need for further treatment by 30 percent. The findings, published in The Lancet Respiratory Medicine, could be ... READ MORE
Amoxicillin is effective for many people hospitalised with pneumonia
Amoxicillin, a narrow-spectrum antibiotic, has been found to be as effective as the broad-spectrum antibiotic co-amoxiclav, which targets a wider range of bacteria, in people admitted to hospital with pneumonia, regardless of how severe it is. In a paper published in the Journal of Infection, a ... READ MORE
Lowering the barriers to participation in brain imaging research
Oxford BRC-supported researchers have produced videos aimed at increasing the diversity of participants taking part in brain imaging research studies. These ‘what to expect’ videos are part of a wider project by the BRC’s Imaging Theme and the University of Oxford’s Wellcome Centre for ... READ MORE
Oxford researchers awarded £11m to address antimicrobial resistance
The National Institute for Health and Care Research (NIHR) has awarded the University of Oxford £11 million to address the major public health threat of antimicrobial resistance. The Oxford Health Protection Research Unit (HPRU) in Healthcare Associated Infections and Antimicrobial Resistance ... READ MORE
Study charts course for next generation of drug targets in autoimmune diseases
In a world first, researchers in Oxford have mapped the cellular dynamics following treatment with the most commonly used advanced therapy in autoimmune diseases. They have discovered why some patients benefit from this therapy while others do not, potentially paving the way for new therapies. ... READ MORE
New biomarker and therapeutic target identified for blood cancers
Researchers in Oxford have identified a protein as a key marker for disease progression and a promising therapeutic target for patients with a type of blood cancer. In a study published in Science Translational Medicine, the team at the University of Oxford’s MRC Molecular Haematology ... READ MORE
Damage to brain’s ‘control centre’ behind long-lasting COVID-19 symptoms, MRI scans show
Damage to the brainstem – the brain’s ‘control centre’ – is behind long-lasting physical and psychiatric effects of severe COVID-19 infection, a study has suggested. Using ultra-high-resolution scanners that can see the living brain in fine detail, researchers from the Universities of Cambridge ... READ MORE
Research at OUH gets £1m funding boost
Oxford University Hospitals (OUH) has received £1 million to fund state-of-the-art research facilities and equipment, much of it to allow its pharmacy team to meet growing demand. The funding was awarded after a competitive process by the National Institute for Health and Care Research (NIHR) ... READ MORE
Funding awarded for world’s first ovarian cancer prevention vaccine
Oxford researchers have been awarded up to £600,000 from Cancer Research UK (CRUK) to create the world’s first vaccine to prevent ovarian cancer. Scientists at the University of Oxford’s MRC Weatherall Institute of Molecular Medicine (MRC-WIMM), led by Professor Ahmed Ahmed, are designing ... READ MORE
New campaign launched to encourage vaccine uptake
Parents are being urged to get their children vaccinated as part of a campaign to boost uptake in the UK amid rising cases of whooping cough and measles. Researchers at the Oxford Vaccine Group, which is part of the University of Oxford and supported by the NIHR Oxford Biomedical Research Centre ... READ MORE
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