Oxford researchers have launched a study to track the spread of COVID-19 in the population and develop a deeper understanding of the virus in general practice. The University of Oxford’s Nuffield Department of Primary Care Health Sciences (NDPCHS) and the Royal College of General Practitioners ... READ MORE
News Archive
Oxford COVID-19 vaccine programme opens for clinical trial recruitment
University of Oxford researchers, working in an unprecedented vaccine development effort to prevent COVID-19, have started screening healthy volunteers ahead of a vaccine trial. The NIHR Oxford Biomedical Research Centre (BRC) provided essential funding to get the trial up and running. The ... READ MORE
Article addresses remote assessment of COVID-19 in primary care
An article by a leading Oxford researcher has outlined the guiding principles on how general practitioners should conduct remote consultations with patients who are suspected of having COVID-19. The article, published in the BMJ, is by Prof Trish Greenhalgh (pictured), the Oxford BRC Theme Lead ... READ MORE
Oxford researchers to play key role in fight-back against COVID-19
Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the ... READ MORE
Researchers identify markers in joint fluid that could be key to cartilage repair
Oxford researchers have found that molecular changes in the joint fluid during knee distraction surgery reveal markers that may drive cartilage repair in osteoarthritis. It is generally accepted that cartilage is not able to heal or regenerate itself after injury or through wear and tear, ... READ MORE
New stroke research centre opens in Oxford
Research into strokes and vascular dementia took a major step forward on Thursday (5th March) with the official opening of the Wolfson Centre for the Prevention of Stroke and Dementia (CPSD) in Oxford, based at the new Wolfson Building at the John Radcliffe Hospital. The new centre is the only ... READ MORE
Molecular Diagnostics theme hosts cancer genomics and immunology seminar
The Molecular Diagnostics theme hosted a very successful seminar, ‘Advanced personalised therapies in gynaecological cancers’, at St Hugh’s College in February 2020. The meeting covered the genomics and immunology of cancer along with the emerging topic of advanced therapeutic medicinal products ... READ MORE
Gene therapy shows promise in tackling common cause of childhood blindness
The results of a first-in-human clinical trial of gene therapy to treat a common cause of genetic blindness have shown partial reversal of sight loss in some patients. X-linked retinitis pigmentosa, caused by mutations in RPGR gene, is the most common cause of blindness in young people. The ... READ MORE
Oxford professors appointed NIHR Senior Investigators
Four leading healthcare academics in Oxford have received a prestigious national award. The University of Oxford professors were named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and prestigious researchers ... READ MORE
Working together to find a cure to HIV
Results from a study testing a new ‘kick and kill’ method of reducing the size of the undetected HIV reservoir in people living with the virus were published in The Lancet this week. RIVER (Research in Viral Eradication of HIV Reservoirs) is the first ever randomised clinical trial to test this ... READ MORE
Link between high cholesterol and aortic valve disease risk found
Oxford researchers have found that while having high cholesterol levels does not influence a person’s risk of aortic or mitral regurgitation, it does increase their risk of developing another major heart valve disease - aortic stenosis. Aortic stenosis is the most common form of heart valve ... READ MORE
New trauma wound treatment no better than standard dressing
A study by Oxford researchers has shown that a new method of treating wounds after major trauma is no more effective at improving surgical infection rates than cheaper standard dressings. The findings, by a team at the Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal ... READ MORE
Almost half of chronic kidney disease is unrecognised
A study by Oxford researchers has found that more than 18 percent of over-60s have chronic kidney disease (CKD), around 44 percent of whom are undiagnosed without screening. CKD is a potentially serious condition, but is associated with few, if any, symptoms. It is thought to affect around 15 ... READ MORE
Short or long sleep associated with pulmonary fibrosis
Scientists have discovered that people who regularly sleep for very long (11 hours or more) or very short (four hours or less) periods of time are two to three times more likely to have the incurable disease pulmonary fibrosis, compared to those that sleep for seven hours in a day. The ... READ MORE
Oxford researchers test ‘Viagra’ drug to prevent recurrent strokes
University of Oxford researchers have begun a clinical trial to assess whether the drug sildenafil, more commonly known by its commercial name Viagra, could improve blood flow to the brain and so have the potential to reduce damage to small blood vessels in the brain and prevent ... READ MORE
Amount of sugar sold in soft drinks drops by 29% in the UK
There was a 29% reduction in the total amount of sugar sold in soft drinks in the UK between 2015-2018, despite an increase in sales of soft drinks by volume of 7%, according to new research supported by the NIHR Oxford BRC. The research, published in BMC Medicine, shows that individual soft ... READ MORE
Researchers identify link in the treatment of inflammatory bowel disease
A new study involving Oxford researchers has revealed how the anti-inflammatory cytokine IL-10 and lipid mediator prostaglandin E2 (PGE2) work together to prevent inflammatory tissue damage and maintain a healthy gut balance. Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) ... READ MORE
Successful Nepal study for typhoid vaccine developed in Oxford
A large field study in Nepal has shown that a typhoid conjugate vaccine (TCV) developed in Oxford is over 81 percent effective in tackling the disease. A single dose of the vaccine was found to be safe and effective in reducing typhoid in children aged 9 months to 16 years in an endemic ... READ MORE
Platelet rich plasma found to be of no benefit in treating torn Achilles tendon
New research from the University of Oxford has shown that platelet rich plasma (PRP) is not effective in treating acute Achilles tendon ruptures. The Achilles tendon is the most common tendon rupture treated in hospitals. Patients face long periods unable to work or participate in sport as ... READ MORE
Severe reactions to grief can be predicted and treated in the first months following a bereavement
Memory, coping strategies and resilience immediately following a loss have been shown to predict the path of a bereaved person’s grief according to new research. The study, published in the Journal of Consulting and Clinical Psychology, also suggested that clinical intervention in the ... READ MORE
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