The first ever trial of microsurgical suture repair versus nerve alignment for digital nerve injuries suggests suture repair does not improve outcomes. Digital nerve injuries are the most common type of nerve injury treated surgically in the UK, often caused by sharp cuts to the ... READ MORE
Study evaluates effectiveness of cancer diagnosis pathway
A major UK study has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue. These NSS can indicate a wide range of conditions, from benign diseases to late-stage ... READ MORE
National registry launched to transform care for people at risk of type 1 diabetes
A first-of-its-kind UK registry for children and adults who are at risk of type 1 diabetes has been launched at the University of Oxford. With more than £600,000 of funding from Diabetes UK, the UK Islet Autoantibody Registry aims to transform how people in the earliest stages of type 1 ... READ MORE
Weight loss alone does not ease atrial fibrillation symptoms, study finds
A clinical trial has found that while a structured weight-loss programme helped older adults with atrial fibrillation (AF) shed weight safely and sustainably, it did not improve their heart rhythm symptoms or reduce the need for further treatment. The findings of the LOSE-AF study, which was ... READ MORE
Home-based heart rhythm screening improves diagnosis of common heart condition
A wearable electrocardiogram (ECG) patch increases diagnosis of a common heart rhythm disorder, according to a study led by researchers at Oxford Population Health. The results of the Active Monitoring for Atrial Fibrillation (AMALFI) trial are published in JAMA (The Journal of the American Medical ... READ MORE
OrganOx in record acquisition for Oxford spin-out
An agreement has been reached for the acquisition of OrganOx, a University of Oxford spin-out company transforming kidney and liver transplantation, by the Japanese medical technology company Terumo Corporation for US$1.5 billion. The transaction, which is subject to regulatory and other ... READ MORE
Oxford researchers create first atlas showing cell interaction in lung fibrosis
Researchers have developed the first mathematically supported cellular map of lung tissue in idiopathic pulmonary fibrosis (IPF) and uncovered key immune cell interactions that could explain why lungs fail to repair in this deadly disease with no known cure. The study by researchers at the ... READ MORE
Elevating voices and dispelling distrust
Corina Cheeks has two important roles with the NIHR Oxford Biomedical Research Centre: she is a member of the Diversity in Research Group, a patient and public involvement and engagement (PPIE) group that aims to make involvement in health research more engaging to diverse communities; and she is ... READ MORE
Recruitment opens for UK-wide liver cancer imaging study
A new UK-wide clinical study aimed at transforming liver cancer surveillance in people with cirrhosis has opened to recruitment. The AMULET study, led by the University of Oxford, is comparing a new MRI technique to standard ultrasound surveillance, with a view to improving early detection of ... READ MORE
More OUH nurses complete BRC internship
Three Oxford University Hospitals (OUH) nurses have completed the first stage of their clinical academic journey after presenting the findings of their Oxford Biomedical Research Centre (BRC) internship research projects. The five-month internships are usually aimed at nurses, ... READ MORE
Study links different genetic pathways causing irregular heartbeats to different risks of stroke
A study led by University of Oxford researchers has established that different biological mechanisms underlying a common heart disorder result in different characteristics and complications. The results, published in Circulation: Genomic and Precision Medicine, could enable more ... READ MORE
UK charity renews funding for Oxford’s ground-breaking MND research
The Alan Davidson Foundation has renewed its commitment to motor neurone disease (MND) research in Oxford by supporting the ACORN study for a further three years. The Alan Davidson Foundation, which began funding ACORN in 2021, will continue to fund a full-time project manager to facilitate the ... READ MORE
Possible druggable target in aggressive leukaemia revealed
Researchers at the University of Oxford have uncovered a potential new therapeutic target in a particularly aggressive and hard-to-treat form of leukaemia. A potential treatment for blast phase myeloproliferative neoplasm (BP-MPN), one of the most aggressive forms of leukaemia, has been ... READ MORE
New research identifies key driver of inflammation in spondyloarthritis
Researchers have identified a possible cause for the protein Interleukin-17 (IL-17) driving inflammatory arthritis, paving the way for the development of targeted therapies to treat the condition. IL-17 is a key inflammatory protein that drives joint inflammation in spondyloarthritis (SpA), a ... READ MORE
Westgate visitors learn about Oxford’s world-class research
Researchers from Oxford’s two NIHR Biomedical Research Centres (BRC) took over the city’s Westgate Centre on Thursday 29 May for their annual Health Research Showcase. Hundreds of half-term visitors, including a large number of children, were able to find out about work of researchers looking ... READ MORE
Academy of Medical Sciences elects two BRC researchers as new Fellows
The Academy of Medical Sciences has elected two NIHR Oxford Biomedical Research Centre scientists to its fellowship in 2025. The new Fellows have been elected to the Academy in recognition of their exceptional contributions to the advancement of biomedical and health science, cutting edge ... READ MORE
First participant recruited to pioneering Parkinson’s trial
A pioneering clinical trial for people with a sleep disorder that puts them at higher risk of developing Parkinson’s has recruited its first UK participant. The trial involves 40 people with iRBD (idiopathic REM sleep behaviour disorder), recruited from the Discovery Cohort study at the ... READ MORE
Study identifies key immune structures in the gut that may drive coeliac disease
Researchers in Oxford have found structures of immune cells in the gut that may be driving the response to gluten in people with coeliac disease and could provide a target for future therapies. The team from the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre ... READ MORE
New guidelines published for monitoring IBD patients to prevent bowel cancer
Researchers and clinicians have developed major new guidelines for the monitoring of patients with inflammatory bowel disease (IBD) to prevent them going on to develop bowel cancer. The new guidelines, developed for the British Society of Gastroenterology by academics at the Universities of ... READ MORE
New study finds common virus may improve skin cancer treatment outcomes
A new study led by University of Oxford researchers has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments. Cytomegalovirus (CMV) is a common virus that, while typically asymptomatic, is carried for life by 50 to 60 ... READ MORE
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