New research has found that deaths linked to spontaneous pneumothorax had been steadily falling in England for more than 15 years, but this progress was disrupted during the COVID‑19 pandemic. Spontaneous pneumothorax is the development of a tiny tear in the outer part of the lung. This causes ... READ MORE
Two Oxford BRC researchers named NIHR Senior Investigators
Two Oxford Biomedical Research Centre (BRC) researchers have been named among the latest cohort of National Institute for Health and Care Research (NIHR) Senior Investigators. Paul Leeson, Professor of Cardiovascular Medicine, and Najib Rahman, Professor of Respiratory Medicine, received the ... READ MORE
Oxford University signs agreement to advance Nipah vaccine candidate
The University of Oxford and Serum Institute of India (SII), the world’s largest vaccine manufacturer, have signed an intellectual property licensing agreement to advance the development and manufacture a vaccine candidate for the deadly Nipah virus. Under the terms of the agreement, SII has been ... READ MORE
Ensuring frail older patients’ voices are heard in our research
We want to be sure that our current and future research is relevant and focuses on what matters most to those who need it. It’s therefore vital that patients, carers and members of the public are encouraged to get involved in that research. Nowhere is this more relevant that in research that aims to ... READ MORE
New research reveals why some oesophageal cancers are hard to treat
Researchers in Oxford have uncovered new insights into why the most aggressive oesophageal cancers are so difficult to treat and how the body’s own defence systems are helping them to thrive. The study, led by Professor Eileen Parkes in the University of Oxford’s Department of Oncology, ... READ MORE
New AI model could improve heart monitoring in hospitals and at home
Researchers have developed a new artificial intelligence (AI) model that could significantly improve how heart conditions are detected, monitored and managed — whether in intensive care units or in people’s own homes. Heart disease remains one of the leading causes of death worldwide. ... READ MORE
OUH receives over £1m for vital research equipment
Oxford University Hospitals (OUH) has received more than £1 million to fund state-of-the-art equipment to expand its research capabilities. The funding was awarded after a competitive process by the National Institute for Health and Care Research (NIHR) as part of its capital funding to NHS ... READ MORE
‘Hidden’ cost of social care after hip fracture exceeds £1.25bn a year in UK, study estimates
Social care following hip fractures costs more than £15,000 per patient every year, according to a new study by Oxford researchers. This amounts to a total cost of £1.25 billion per year. Hip fracture is the most common serious injury in older adults, affecting over 80,000 people in the UK ... READ MORE
Drugs identified that could help prevent delirium after surgery
A new study has found that several commonly used drugs could significantly reduce the risk of delirium in older people following surgery. Delirium – a sudden state of confusion and memory problems – affects around one in seven older adults after an operation. People who get delirium spend ... READ MORE
Study warns of risks in AI chatbots giving medical advice
The largest user study of large language models (LLMs) for assisting the general public in medical decisions has found that they present risks to people seeking medical advice due to their tendency to provide inaccurate and inconsistent information. The research reveals a major gap between the ... READ MORE
Study tests whether deep brain stimulation can treat chronic pain
The first three patients have undergone revolutionary brain surgery in a bid to treat the chronic pain they have experienced since suffering a stroke. A research study by Oxford neurosurgeons and engineers is trialling whether deep brain stimulation (DBS) – delivering an electrical pulse into ... READ MORE
New Kadoorie Institute for Trauma, Emergency and Critical Care established
Oxford Trauma and Emergency Care at the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), along with the Critical Care Research Team at the Nuffield Department of Clinical Neurosciences (NDCN) have formally become a new institute within the University of ... READ MORE
Surgery unnecessary for elbow fractures in children, new study finds
Researchers in Oxford and Liverpool have found that surgery for a common elbow fracture in children offers no clinical benefit compared to non-surgical care. The findings could have significant implications for treatment and offer significant cost savings to the NHS. Published in The Lancet, ... READ MORE
Public contributors make recommendations for involving underserved communities in research
A group of patient and public involvement contributors have developed some key recommendations for researchers when engaging with under-served communities, including ensuring that the right people were involved, building relationships and being mindful of practicalities, such as payment and ... READ MORE
Study suggests blood pressure care after giving birth could protect brain health
Women who develop high blood pressure during pregnancy may be able to protect their long‑term brain health through better blood pressure management soon after giving birth, according to a new study by Oxford researchers. The study found that women who monitored and managed their blood pressure ... READ MORE
Night-time changes in metabolism may be driving common liver disease, study finds
Researchers at the University of Oxford have discovered that the most common liver disease follows a strong day-night pattern, and the metabolic changes that drive the disease are most pronounced overnight, when the body is least able to process sugar and fat. Furthermore, they found that these ... READ MORE
New NIHR Oxford Senior Research Fellows named
Eight mid-career researchers identified as having the potential to become future translational research leaders have been appointed as the next cohort of NIHR Oxford Senior Research Fellows. The selection process was a coordinated effort by the NIHR Oxford Biomedical Research Centre (BRC) and ... READ MORE
Oxford team treats first patient in ground-breaking retinal gene therapy trial
The first patient has been treated in Oxford in the second phase of an international clinical trial testing a new gene therapy for Stargardt disease - a rare inherited eye condition that leads to progressive vision loss and eventually blindness in children and adults. The ASTRA trial is ... READ MORE
Stopping weight-loss drugs linked to faster regain than ending diet programmes, review finds
People tend to regain weight rapidly after stopping weight-loss drugs – and faster than after ending behavioural weight loss programmes – according to a new systematic review and meta-analysis from the University of Oxford published in The BMJ. The findings come as real-world data shows around ... READ MORE
Oxford recruits first patient in Europe for heart inflammation treatment study
An international clinical trial to test a potential treatment for people with coronary inflammation has got under way at Oxford University Hospitals. The FORTIFY study was launched at the Acute Multidisciplinary Imaging and Interventional Centre (AMIIC), a state-of-the-art facility within the ... READ MORE
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