Background What we did We recruited two public contributors from the BRC’s Diversity in Research Group in developing our grant application, particularly our Equality, Diversity and Inclusion strategy. The two public contributors were co-applicants, attended multiple meetings, including ... READ MORE
Case Studies
PPIE CASE STUDY CATEGORIES
Cancer | Cardiovascular Medicine | Diabetes and Metabolism | Digital Health from Hospital to Home | Genomic Medicine | Haematology and Stem Cells | Imaging | Life-saving Vaccines | Metabolic Experimental Medicine | Musculoskeletal | Obesity, Diet and Lifestyle | Respiratory Medicine | Stroke and Vascular Dementia | ALLObesity, Diet and Lifestyle Theme
New remission care pathway: Diabetes Adaptive Weight management Network (NewDAWN). Background For people recently diagnosed with type 2 diabetes who are overweight, losing weight can put their diabetes into remission. Remission means they have normal blood glucose without needing diabetes ... READ MORE
Digital Health from Hospital to Home Theme
Enhanced Recovery After Critical Care (ERACC): Developing and Testing a Care Pathway for Patients Discharged From an Intensive Care Unit. Background Patients discharged from intensive care often receive less than high quality aftercare. We planned to design and test an “Enhanced Recovery After ... READ MORE
Stroke and Vascular Dementia Theme
Background Over half of all patients admitted to hospital are aged 65 or older, and many of them have several long-term health conditions. However, hospital services have not developed sufficiently to meet the needs of these patients who may be frail or have dementia or delirium (new or worsened ... READ MORE
Respiratory Medicine Theme
Background The academic research group in the Respiratory Medicine Theme have recruited over 500 individuals to clinical trials and observational studies over the last 5 years.We have found the airway disease community to be extremely helpful with this endeavour.We wanted to find a way to thank ... READ MORE
BOOST: Better Outcomes for Older people with Spinal Trouble
Background This 5-year programme focuses on the management of back pain in older people. What we did During the application process we formed a PPI (patient and public involvement) group and worked closely with them. We advertised for PPI representatives via the NIHR-INVOLVE website and ... READ MORE
Nailbed injury treatments in children (NINJA)
Background We ran a pilot for a study comparing outcomes in treatments for nailbed injuries in children. The pilot highlighted a few issues we needed to address – mainly completion of the follow up assessments, patient retention and outcomes. What we did We ran a focus group with six ... READ MORE
The World Hip Trauma Evaluation
What we did We performed a series of formal qualitative interviews with hip fracture patients and their carers (NIHR RPDG-1210-10022). We explored the patients’ experience of hip fracture and their expectations of recovery from their injury. The patients’ priorities regarding outcome were then ... READ MORE
The RUDY Patient Forum
Background RUDY Study is a novel web-based platform for participants with rare diseases supporting patient-driven research, allowing online registration, data collection, two-way communication and dynamic consent.This case study highlights the valuable contribution of the RUDY Patient ... READ MORE
Metabolic Experimental Medicine: The Diamond Study
Background Recent research shows it may be possible to treat people with type 2 diabetes with an intensive weight loss programme, known as a total diet replacement (TDR) programme. TDR provides 800 calories per day in the form of commercially produced soups, shakes and bars, but little or no ... READ MORE
TB043 and TB044 studies, Jenner Institute Oxford
Background The TB043 study is a human challenge study to evaluate innate and adaptive immune responses to a controlled human infection with BCG, administered by the aerosol inhaled route in healthy, BCG-naïve, UK adult volunteers. BCG stands for Bacillus Calmette-Guérin vaccine, designed to ... READ MORE
FLU008 study, Jenner Institute Oxford
Background The FLU008 study was a phase I, open label study to determine the safety and immunogenicity of candidate influenza vaccine MVA-NP+M1, manufactured on the AGE1.CR.pIX novel avian cell line. Earlier trials had already shown this vaccine to be safe and effective in producing an immune ... READ MORE
BRAIN LINK Building better brain research
Background The Wellcome Centre for Integrative Neuroimaging (WIN) studies the brain, with the aim of understanding disease mechanisms and treatment. The Brain Link project connects people with lived experience of the conditions we study with researchers, ensuring our research becomes more ... READ MORE
Haematology and Stem Cell Theme
Background Around 3-4% of people will develop either lymphoma or Chronic Lymphocytic Leukemia (CLL) during their lifetime. Lymphomas are the 5th most common cancer in the UK. Research has focused on treatments and cure, but patients sometimes also have other priorities.We want to ensure ... READ MORE
Patient involvement in research into genetic testing
Background Oxford’s Genomic Medicine Theme works closely with Headlines, the UK-based charity supporting those with craniosynostosis and other rare craniofacial conditions. This case study shows how the Headlines patient group helped identify research priorities and subsequent research ... READ MORE
Recovery following intensive care treatment: REFLECT
Background With the support of the NIHR Research Design Service, the critical care research study team invited a small number of patient and public representatives to attend a focus group to discuss the design and development of the study on improving care for people after leaving intensive care ... READ MORE
Diabetes and Metabolism Theme
Background What we did What difference did it make ... READ MORE
CardioThoracic Public Involvement Panel
Background Find out more about the CTPIP group What we did What difference did it make CTPIP members: Find out more about the DTPIP group ... READ MORE
Decision aid for people with Hodgkin lymphoma
Background We were asked by a colleague, Dr Rebecca Shakir, for input into a forthcoming research project. Rebecca developed a decision aid for people with Hodgkin lymphoma (HL) who will be faced with a choice about whether to have mediastinal radiotherapy after a course of chemotherapy. ... READ MORE