The Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded £7.8 million by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential. The awards will fund research into ... READ MORE
News Archive
Blood test developed to identify those at risk of developing Parkinson’s
Research carried out at the University of Oxford has led to the development of a new blood-based test to identify the pathology that triggers Parkinson’s disease before the main symptoms occur. This could allow clinicians to screen for those individuals at high risk of developing the disease and ... READ MORE
Small cash incentives improve vaccine uptake in rural areas of Ghana
Researchers from Oxford and Ghana have shown that small cash incentives increased COVID-19 vaccine uptake in rural Ghana. The findings, published in Nature Medicine, could offer a new strategy for enhancing health interventions in Africa. The recent COVID-19 pandemic highlighted the ... READ MORE
“Don’t think ‘someone else can do it’; you need to be that person.”
Research participant profile: Maryam Masood was diagnosed with ulcerative colitis at the age of 20. But that had followed three years of symptoms and uncertainty about what was causing them. She is now taking part in research trials supported by the NIHR Oxford Biomedical Research Centre (BRC), ... READ MORE
Oxford receives European funding for paediatric diabetes research
Oxford researchers have received funding from a European programme to investigate how to best follow up children who are at risk of type 1 diabetes (T1D). Oxford will receive 433,000 euros as part of the EDENT1FI programme which aims to identify T1D at its pre-clinical stage in children in the ... READ MORE
AI tool could help thousands avoid fatal heart attacks
An AI tool that can predict 10-year risk of deadly heart attacks, could transform treatment for patients who undergo CT scans to investigate chest pain, according to research supported by the NIHR Oxford Biomedical Research Centre (BRC). In the first real-world trial of the AI tool, it was ... READ MORE
Heart attack risk decreased in new mothers by self-monitoring blood pressure at home
Self-monitoring blood pressure after giving birth could help to cut new mothers’ risk of future heart disease and strokes, according to new research by Oxford researchers. The study, funded by the BHF and supported by the NIHR Oxford Biomedical Research Centre (BRC), could be the first step ... READ MORE
New insight into immune-pathology in COVID-19 lungs
A study by Oxford researchers has provided new insights into how immune cells interact in the lungs of patients with severe COVID-19. In a damaged lung with a massive cell infiltrate, as seen with severe COVID-19 infection, it can be difficult to determine which cells are involved in ... READ MORE
Partnership with Danaher paves way for precision medicine test for sepsis
The University of Oxford today announced a partnership with Danaher Corporation to develop a new test to enable precision medicine care for sepsis, a pathological immune response to infection that accounts for one in five deaths globally each year. The test will build on research from the ... READ MORE
RECOVERY trial expands to investigate treatments for influenza
The RECOVERY trial, which discovered four effective treatments for COVID-19, has expanded to investigate treatments for influenza. Globally, seasonal flu epidemics are estimated to kill between 290,000 and 650,000 people every year. Despite having known about influenza for almost a ... READ MORE
Study reveals inequalities in access to shoulder replacement surgery
As demand for shoulder replacement surgery grows, a new study finds that up to one in six patients are having to travel to a different region for surgery, and exposes a year-on-year increase in the risk of serious adverse events after surgery that require admission to hospital. Shoulder pain ... READ MORE
WHO recommends Oxford malaria vaccine for use
The R21/Matrix-MTM malaria vaccine developed by the University of Oxford and the Serum Institute of India has been recommended for use by the World Health Organisation (WHO), paving the way for its global roll-out. The WHO made the announcement after the vaccine, developed with support from the ... READ MORE
Collaboration announced for develop use of AI to evaluate Barrett’s oesophagus
Technology to get more accurate readings of the pre-cancerous condition Barrett’s oesophagus that was devised in a study supported by the NIHR Oxford Biomedical Research Centre (BRC) is to be developed as part of a new collaboration between the University of Oxford and Satisfai Health, a ... READ MORE
Longer-term organ abnormalities confirmed in some post-hospitalised COVID patients
A study looking at the longer-term impact of COVID-19 has found that nearly a third of patients admitted to hospital with COVID-19 displayed abnormalities in multiple organs five months after being discharged. Some of these abnormalities have been shown through previous work to be evidence of ... READ MORE
Research profile: “You see the impact of your research in clinical care. It’s part of the same circle”
Lizzie Stafford, a Clinical Research Nurse Manager in the Nuffield Department of Medicine, has been involved in number of Oxford BRC-supported research studies. The BRC is funding the second year of her NIHR postgraduate clinical research programme. “I’ve been involved in some ground-breaking ... READ MORE
Blood clots during COVID-19 may cause ongoing cognitive problems
High levels of two proteins at the time of COVID-19 have been found in patients who later experienced cognitive problems, including ‘brain fog'. The findings give a major clue as to one cause of their symptoms: blood clots. Researchers from the University of Oxford looked at blood tests from ... READ MORE
New Pharmacy Clinical Trials Unit paves way for trialling new therapies
Oxford University Hospitals’ (OUH) ability to help develop ground-breaking new therapies has been given a boost with the opening of a new temporary Pharmacy Clinical Trials Unit (CTU). Based on the Churchill Hospital site, the facility will be used to handle and prepare a new range of medicines ... READ MORE
Tumour monocyte content can predict immunochemotherapy outcomes, study shows
A team of Oxford researchers has discovered a link between immune cells known as monocytes in tumours and overall survival in patients with oesophageal cancer. A study by Ludwig Cancer Research, supported by the NIHR Oxford Biomedical Research Centre (BRC) found that the presence of relatively ... READ MORE
Research profile: Clinical nurses helping to shape our medical knowledge
Yuhan Zhang is an Advanced Nurse Practitioner in Oxford University Hospitals’ Ambulatory Outreach Team. She is also in the second year of a nursing doctorate at Oxford Brookes University, for which she is getting support from the NIHR Oxford Biomedical Research Centre (BRC). Yuhan works in an ... READ MORE
Real-world vaccine response in patients with impaired immune systems revealed
Updated data from the ongoing OCTAVE study reveal, for the first time, the real-world vaccine responses and infection outcomes in clinically at-risk patients with a range of immunocompromised or immunosuppressed conditions. Preliminary data from the landmark OCTAVE study in August 2021 showed ... READ MORE
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