A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University of Oxford and the Wellcome Sanger Institute identified high levels of a specific receptor in immune cells from psoriatic arthritis patients, giving the ... READ MORE
NIHR health talks feature during Oxford IF festival
The Oxford BRC has joined with other parts of the local National Institute of Health Research infrastructure to organise a series of online talks as part of this year’s Oxford IF science and ideas festival. The talks, by leading Oxford researchers, cover a wide range of topics, from diabetes to ... READ MORE
‘Awake proning’ associated with improved COVID-19 clinical outcomes
A study by Oxford respiratory researchers has found that putting COVID-19 patients in a prone position can lead to improved outcomes. The findings of this retrospective study, supported by the NIHR Oxford Biomedical Research Centre, were published in an article by BMJ Open Respiratory ... READ MORE
RECOVERY Trial to test ‘antibody cocktail’
The RECOVERY Trial, the world’s largest randomised trial to find effective COVID-19 treatments, will evaluate the impact of an anti-viral antibody cocktail developed to tackle the virus. The announcement was made on 14 September by Regeneron Pharmaceuticals and the University of Oxford, which ... READ MORE
Persistent immune memory of COVID-19 found in recovered patient T cells
Oxford University researchers have found that infection with COVID-19 produces a robust T cell response, including inducing T cell ‘memory’ to potentially fight future infections. The results, published in Nature Immunology, are a joint effort from the Oxford COVID-19 immunology group, led ... READ MORE
Study explores COVID-19 outcomes for liver transplant patients
A study involving Oxford researchers has found that having had a liver transplant does not increase the risk of death from COVID-19, but that other factors such as age and comorbidities among liver transplant recipients do. The researchers from the Oxford Liver Unit, based at Oxford University ... READ MORE
Eight BRC projects get RCF funding
Eight Oxford BRC proposals, many covering a number of themes, have been awarded NIHR Research Capability Funding (RCF) funding to take forward key areas of research. The selected projects that will be supported include: Developing a research centre devoted to urgent and acute careThe ... READ MORE
Health economists outline possible criteria for allocating COVID-19 vaccine
NIHR Oxford BRC-supported health economics researchers have published a paper outlining the possible criteria that governments might use to prioritise who gets a COVID-19 vaccine once one has been approved for use. The article - ‘How Should a Safe and Effective COVID-19 Vaccine be Allocated? ... READ MORE
Low-dose corticosteroids found to reduce mortality in patients with severe COVID-19
Oxford patients, clinicians and researchers have contributed important data to new global research which shows that corticosteroids can significantly improve outcomes for severely ill patients with COVID-19. Four research papers published today in the Journal of the American Medical Association ... READ MORE
Research photography exhibition moves to Didcot
A photography exhibition showcasing ground-breaking NHS research taking place across the Thames Valley has opened in Didcot. ‘The Body Unlocked: How Research is Changing Lives’ features life-sized photographs of people who have taken part in studies, researchers at work and microscopic ... READ MORE
Hydroxychloroquine study finds increased cardiovascular risk with azithromycin
The combination of hydroxychloroquine (HCQ) and azithromycin (AZM) has been linked to significant cardiovascular risks, including mortality, in the largest safety study ever performed on both HCQ and HCQ+AZM. This network study, led by the Observational Health Data Sciences and Informatics ... READ MORE
Test developed to identify new-borns at risk of leukaemia
Oxford researchers have developed a new method to quickly identify cancerous cells in babies at risk of leukaemia. The team hope that the new protocol could make rapid testing more accessible for clinical laboratories around the globe. Until now, the only reliable way to know if a baby with ... READ MORE
Paper outlines management of post-acute COVID-19 in primary care
A new article published in the BMJ has mapped out what is known and what is still unknown about ‘long COVID’, where patients COVID-19 patients continue to experience symptoms many weeks after contracting the virus. The article, co-authored by the NIHR Oxford BRC’s Theme Lead for Partnerships ... READ MORE
Common heart medication does not increase risk of COVID-19 hospitalisation
A study by Oxford researchers, supported by the NIHR Oxford Biomedical Research Centre (BRC), found that ACE inhibitors and ARBs – both common treatments for high blood pressure and heart failure – are not generally linked to an increased risk of severe COVID-19 disease or an increased likelihood of ... READ MORE
BRC gets European funding for citizen science metabolism project
The NIHR Oxford Biomedical Research Centre (BRC) has received more than €270,000 from the European Commission as a part of a multi-nation research project to promote citizen science. Oxford’s involvement will entail the BRC and the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) ... READ MORE
Oxford University and ZOE partner on COVID-19 treatment trials
The University of Oxford has joined forces with the COVID Symptom Study app to widen access to two clinical trials of potential treatments for COVID-19. The two trials include the STOIC trial, which is supported by the NIHR Oxford BRC. Run by the University’s Nuffield Department of Medicine ... READ MORE
Study maps role CD8 T cells play in IBD
Researchers in Oxford using an ‘atlas’ of immune cells in the human colon have found evidence of the role of CD8 T cells in inflammatory bowel disease (IBD). The findings could lead to a better understanding of how cells behave and interact in people with IBD, and could pave the way for more ... READ MORE
Mild COVID-19 symptoms might not result in positive antibody test, research finds
Oxford researchers have found that COVID-19 antibody tests might not give a positive result if people have only had mild symptoms, like loss of taste and smell. Microbiology and data experts from the Oxford University Hospitals (OUH) NHS Foundation Trust and the University of Oxford made the ... READ MORE
BRC researchers’ work recognised with Vice-Chancellor’s Awards
A number of Oxford BRC-supported researchers have been recognised in this year’s University of Oxford Vice-Chancellor Innovation Awards. The Vice-Chancellor Innovation Awards celebrate research-led innovation that is having societal or economic impact. Prof Robert MacLaren, who leads the BRC’s ... READ MORE
AI test identifies COVID-19 within an hour in emergency departments
University of Oxford scientists specialising in infectious disease and clinical machine learning have developed an artificial intelligence test that can rapidly screen for COVID-19 in patients arriving in emergency departments. The initial findings of the ‘CURIAL’ AI test, which has been ... READ MORE
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