NIHR Oxford Biomedical Research Centre

Enabling translational research through partnership

MENUMENU
  • About
    • About the NIHR Oxford Biomedical Research Centre
    • Activities during COVID-19
    • Strategic Partnership Board
    • Steering Committee
    • Promoting Equality, Diversity and Inclusion in Research
    • Current Vacancies
    • Contact Us
    • Stay in Touch
  • Research
    • Research Themes Overview
    • Cancer
    • Cardiovascular Medicine
    • Digital Health from Hospital to Home
    • Gene and Cell Therapy
    • Genomic Medicine
    • Imaging
    • Inflammation across Tissues
    • Life-saving Vaccines
    • Metabolic Experimental Medicine
    • Modernising Medical Microbiology and Big Infection Diagnostics
    • Musculoskeletal
    • Preventive Neurology
    • Respiratory Medicine
    • Surgical Innovation, Technology and Evaluation
    • Translational Data Science
  • Patient & Public Involvement
    • Getting involved with research
    • View and register for involvement opportunities
    • Patient & Public Groups
    • Patient and Public Involvement Advisory Group
    • Diversity in Research Group
    • Oxford Blood Group
    • Case Studies
    • PPIE Strategy
    • PPIE News
    • PPI Researcher Guidance
    • Researchers: Post a PPIE opportunity
  • Training Hub
    • Training Hub Overview
    • Clinical Academic Pathway
    • Internships
    • Preparatory Research Fellowships
    • Senior Research Fellowships
    • Research Training Bursaries
    • Doctoral Awards
    • Post-Doctoral Awards
    • Other funding
    • Leadership Training
    • Useful Links
    • Training and Education Resources
    • Upcoming Training Events & Courses
  • Industry
    • Collaborate with Oxford BRC
    • Who Do We Work With?
    • Events
    • Further Information and Additional Resources
    • Contacts for Industry
  • Videos
  • News
  • Events
Research Theme

Modernising Medical Microbiology and Big Infection Diagnostics

Home > Research Themes Overview > Modernising Medical Microbiology and Big Infection Diagnostics > Infections in Oxfordshire Research Database > IORD Projects

IORD – Ongoing approved projects and project outputs

  • IORD Categories

  • Order by

  • Search

Analysis of trends in mortality rates following infection with SARS-CoV-2 in patients with underlying haemato-oncology diagnoses at Oxford University Hospitals

ONGOING
IORD category: Antimicrobial Resistance and Antibiotics, Electronic Health Records
Chief Investigator: Prof David Eyre · Sponsor: OUH · Research location: OUH NHS Trust · Approval date: 11 Nov 2022

Antimicrobial resistance is a growing threat to public health worldwide. In hospitals, if antibiotics do not treat severe infections effectively this can lead to more deaths and longer hospital stays. However, prompt adjustments to antibiotic treatments to switch to an antibiotic that works may ... READ MORE

Global Research on AntiMicrobial resistance (GRAM) Project

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, Specific Infections
Chief Investigator: Professor Susanna Dunachie · Sponsor: Oxford University · Research location: Oxford University · Approval date: 05 May 2020

The Global Research on AntiMicrobial resistance (GRAM) Project is the flagship study of the Oxford GBD (Global Burden of Disease) Group, and aims to provide robust, comprehensive and timely evidence of the burden of antimicrobial resistance (AMR) in 195 countries and territories. The Oxford GBD ... READ MORE

The impact of SARS-CoV-2 on hospital admissions, antimicrobial prescribing and serious bacterial infections

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, COVID-19
Chief Investigator: Prof Sarah Walker · Sponsor: OUH · Research location: Oxford University · Approval date: 05 May 2020

The Covid-19 pandemic is having a profound impact on healthcare globally. Whilst the virus is directly devastating for many suffering from severe infection, there are also wider implications. These include potentially lower use of healthcare for other serious conditions with potential adverse ... READ MORE

Impact of antibiotics on detection and transmission of MRSA

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, Specific Pathogens
Chief Investigator: Dr David Eyre · Sponsor: OUH · Research location: Oxford University · Approval date: 02 Jul 2019

Antibiotics are commonly used to treat infections, but they may also affect how other infections are detected and transmitted. MRSA is a potentially serious healthcare-associated infection. Over the past decade there has been major progress in reducing the number of patients who carry MRSA on their ... READ MORE

Can we estimate resistance in bloodstream infections from resistance in other types of specimen?

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, Specific Infections
Chief Investigator: Prof Tim Peto · Sponsor: OUH · Research location: Oxford University · Approval date: 17 Sep 2018

In order to reduce the threat of antimicrobial resistance, a first key step is to understand how much resistance there is. This is typically done by looking at bacteria causing serious infections, particularly bloodstream infections. However, growing bacteria from blood usually requires ... READ MORE

Antimicrobial prescribing and risk of future resistant infection

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics
Chief Investigator: Dr Nicola Fawcett · Sponsor: OUH · Research location: Oxford University · Approval date: 23 Mar 2018

Infections due to one particular family of bacteria called Enterobacteriaceae are increasing in Oxfordshire and worldwide, as are infections resistant to the commonly-used beta-lactam antibiotics (such as co-amoxiclav, sometimes also called augmentin). Treating people with particular types of ... READ MORE

Antibiotic use – if you use less antibiotic in general medicine are there adverse consequences?

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics
Chief Investigator: Profs Sarah Walker & Tim Peto · Sponsor: OUH · Research location: OUH NHS Trust · Approval date: 19 Mar 2015

Reducing antibiotic use to combat antimicrobial resistance is a priority. We want to know if we can do this safely and without putting patients at undue risk. Antibiotic use was measured over 1 week in an intensive audit of practice in the Acute/General Medicine service at the John Radcliffe. This ... READ MORE

Trends in bacterial pathogens, antibiotic resistance, antibiotic usage and patient outcomes in critical care in the Oxford University NHS Trust hospitals, 1999-2014

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, Electronic Health Records, Specific Pathogens
Chief Investigator: Dr Nicole Stoesser · Sponsor: OUH · Research location: Oxford University · Approval date: 12 Jan 2015

Antibiotics are medicines that are hugely important in treating many infections, and antibiotic resistance is a major clinical problem. Research has shown that increased use of antibiotics, whether appropriate or inappropriate, seems to be associated with higher numbers of antibiotic-resistant ... READ MORE

Antimicrobial susceptibility profiles of urinary isolates from samples collected in the community

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics
Chief Investigator: Dr Kyle Knox · Sponsor: OUH · Research location: OUH NHS Trust · Approval date: 04 Jul 2014

Urinary tract infections comprise around 1% of the 300 million general practice consultations annually in the UK; most of these are acute uncomplicated UTIs (AUUTIs) in women of childbearing age. AUUTIs affect around 50% of women during their lifetime and, by 24 years of age, one-third of women have ... READ MORE

Modernising Medical Microbiology and Big Infection Diagnostics

  • Modernising Medical Microbiology and Big Infection Diagnostics
  • Sub-theme 1: Novel rapid, high-throughput diagnostic workflows for infection
  • Sub-theme 2: Big data-led infection diagnosis and management strategies
  • Infections in Oxfordshire Research Database (IORD)
    • IORD Projects
  • Contacts
  • Videos
  • News

Subscribe to the Oxford BRC Newsletter

Keep informed about the work of the Oxford BRC by subscribing to our Mailchimp e-newsletter. It is produced several times a year and delivers news and information about upcoming events straight to your inbox.

Subscribe Now

Oxford BRC on Social Media

  • Facebook
  • LinkedIn
  • Twitter
  • YouTube

Feedback

We’d love to hear your feedback. Please contact us at obrcenquiries@ouh.nhs.uk

  • Data Control and Privacy
  • Accessibility
  • Our Partners
  • Disclaimer
  • Contact

Copyright © 2023 NIHR Oxford Biomedical Research Centre