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Research Theme

Modernising Medical Microbiology and Big Infection Diagnostics

Home > Research Themes Overview > Modernising Medical Microbiology and Big Infection Diagnostics > Infections in Oxfordshire Research Database > IORD Projects > Impact of antibiotics on detection and transmission of MRSA

IORD Project

Impact of antibiotics on detection and transmission of MRSA

COMPLETED
IORD category: Antimicrobial Resistance and Antibiotics, Specific Pathogens
Chief Investigator: Dr David Eyre
Sponsor: OUH
Research location: Oxford University
Approval date: 02 Jul 2019

Antibiotics are commonly used to treat infections, but they may also affect how other infections are detected and transmitted. MRSA is a potentially serious healthcare-associated infection. Over the past decade there has been major progress in reducing the number of patients who carry MRSA on their skin and other body sites, and in reducing infections due to MRSA. We plan to use mathematical models to investigate how antibiotic use in affects the transmission of MRSA. Using data from the Oxford adult intensive care unit, for several different antibiotics, we will consider the effect of each antibiotic on detection of MRSA by screening tests (nose swabs), susceptibility to acquisition of MRSA carriage, and the chance of onward transmission from known carriers.

See publication: Probabilistic modelling of effects of antibiotics and calendar time on transmission of healthcare-associated infection

Modernising Medical Microbiology and Big Infection Diagnostics

  • Modernising Medical Microbiology and Big Infection Diagnostics
  • Sub-theme 1: Novel rapid, high-throughput diagnostic workflows for infection
  • Sub-theme 2: Big data-led infection diagnosis and management strategies
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