News for Inflammation across Tissues

Eight BRC projects get RCF funding

7 September 2020 · Listed under Cancer, Cardiovascular Medicine, Digital Health from Hospital to Home, Gene and Cell Therapy, Genomic Medicine, Imaging, Inflammation across Tissues, Metabolic Experimental Medicine, Molecular Diagnostics, Multimorbidity and Long-Term Conditions, Preventive Neurology, Surgical Innovation, Technology and Evaluation, Translational Data Science

Eight Oxford BRC proposals, many covering a number of themes, have been awarded NIHR Research Capability Funding (RCF) funding to take forward key areas of research. The selected projects that will be supported include: Developing a research centre devoted to urgent and acute careThe ... READ MORE

Study maps role CD8 T cells play in IBD

3 August 2020 · Listed under Inflammation across Tissues

Researchers in Oxford using an ‘atlas’ of immune cells in the human colon have found evidence of the role of CD8 T cells in inflammatory bowel disease (IBD). The findings could lead to a better understanding of how cells behave and interact in people with IBD, and could pave the way for more ... READ MORE

BRC funds three further COVID-19 studies

21 April 2020 · Listed under COVID-19, Gene and Cell Therapy, Inflammation across Tissues, Life-saving Vaccines

Three more studies are being funded by the NIHR Oxford Biomedical Research Centre (BRC) to look at the way the body interacts with COVID19; these include assessing the safety of a new vaccine; the role that antibodies might play in plasma therapy; and blood biomarkers that determine adverse ... READ MORE

Common antibody test can be adapted for COVID-19, study finds

20 April 2020 · Listed under COVID-19, Inflammation across Tissues, Modernising Medical Microbiology and Big Infection Diagnostics

Research led from Oxford has found that an immunological assay commonly used to measure antibodies, antigens and proteins in biological samples can be specifically adapted to detect and quantifying COVID-19 antibodies. The investigations by the National COVID Testing Scientific Advisory ... READ MORE

Oxford researchers to play key role in fight-back against COVID-19

20 March 2020 · Listed under COVID-19, Inflammation across Tissues, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics, Partnerships for Health, Wealth and Innovation, Respiratory Medicine, Translational Data Science

Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the ... READ MORE

Oxford professors appointed NIHR Senior Investigators

24 February 2020 · Listed under Inflammation across Tissues, Surgical Innovation, Technology and Evaluation

Four leading healthcare academics in Oxford have received a prestigious national award. The University of Oxford professors were named National Institute of Health Research (NIHR) Senior Investigators in recognition of being “among the most prominent and prestigious researchers ... READ MORE

Researchers identify link in the treatment of inflammatory bowel disease

13 December 2019 · Listed under Inflammation across Tissues

A new study involving Oxford researchers has revealed how the anti-inflammatory cytokine IL-10 and lipid mediator prostaglandin E2 (PGE2) work together to prevent inflammatory tissue damage and maintain a healthy gut balance. Inflammatory bowel diseases (IBD), which include Crohn’s disease (CD) ... READ MORE

Researchers find new cells that repair tissue

18 September 2019 · Listed under Inflammation across Tissues

Researchers at Oxford University have discovered that a newly discovered group of cells can help repair tissues in the body. The researchers, who are supported by the NIHR Oxford Biomedical Research Centre, say these cells, which are abundant in our bodies, could be harnessed to help heal ... READ MORE

Oxford patients take part in study to understand role of stress in managing Crohn’s disease

27 June 2019 · Listed under Digital Health from Hospital to Home, Inflammation across Tissues

Around 60 Oxford University Hospitals (OUH) NHS Foundation Trust patients are to take part in a study to look at how wearable and mobile devices can help us to understand the relationship between stress and the symptoms of Crohn’s disease, and help to improve management of the condition. The ... READ MORE

BRC researchers elected Fellows of Academy of Medical Sciences

8 May 2019 · Listed under Inflammation across Tissues, Life-saving Vaccines, Modernising Medical Microbiology and Big Infection Diagnostics

Three Oxford BRC-supported researchers are among eight University of Oxford scientists elected to join the prestigious Fellowship of the Academy of Medical Sciences (AMS) this year. The BRC researchers among the new Fellows are: Professor Helen McShane, Professor of Vaccinology in the ... READ MORE

Research identifies how the gut loses protective barrier function in IBD

27 February 2019 · Listed under Inflammation across Tissues

A University of Oxford research team has used single-cell technology to identify new players in the gut epithelial barrier, the single-cell layer that forms the lining of the small and large intestine. The team from the MRC Human Immunology Unit (HIU), whose paper was published in the journal ... READ MORE

Study suggests immune system plays key role in survival after pancreatic cancer surgery

12 February 2019 · Listed under Cancer, Inflammation across Tissues

Researchers in Oxford have found that an individual’s immune system – and in particular the presence of T-cells amongst tumour cells - may play an important role in survival after surgery to remove pancreatic cancer. The study by the University of Oxford’s Department of Oncology and Kennedy ... READ MORE

Oxford researcher gets additional prize for his research into immunology of asthma

15 August 2018 · Listed under Inflammation across Tissues, Respiratory Medicine

A University of Oxford researcher has been awarded a top scientific prize to add to a prestigious fellowship he was given in June. Dr Tim Hinks was awarded the £25,000 Wellcome-Beit Prize for his research into the immunology of lung diseases, including asthma. The prize is given to four ... READ MORE

Stem cell transplants to be used in treating Crohn’s disease

6 August 2018 · Listed under Inflammation across Tissues

A new clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn’s disease. Oxford University Hospitals NHS Foundation Trust is one of the centres where the trial will be conducted, and where patients will be recruited. Research at ... READ MORE

Oxford researcher gets £1m boost to study immunology of asthma

14 June 2018 · Listed under Inflammation across Tissues, Respiratory Medicine

A University of Oxford researcher has received a £1m grant to expand his research into the immunology of lung diseases, including asthma. Dr Tim Hinks has been awarded a Wellcome Trust Clinical Research Career Development Fellowship. The funding that comes with the award will allow Dr Hinks, who ... READ MORE

Online tool allows patients with ulcerative colitis to manage condition

17 April 2018 · Listed under Inflammation across Tissues

An online tool that allows people with a form of inflammatory bowel disease (IBD) to manage their own condition and reduce hospital visits is being rolled out to more patients in Oxford. The decision to expand use of the True Colours platform for people with ulcerative colitis follows a ... READ MORE

Killer T cells show their kinder side, BRC researchers reveal

27 March 2018 · Listed under Inflammation across Tissues

The immune system protects the body by responding to invading organisms, but how is an attack on useful resident microbes prevented? Two NIHR Oxford BRC researchers have identified a pathway that allows immune cells to sense and respond to beneficial bacteria. The article by the Oxford BRC’s ... READ MORE

Oxford medical researchers win prestigious national awards

23 February 2018 · Listed under Gene and Cell Therapy, Inflammation across Tissues, Life-saving Vaccines, Metabolic Experimental Medicine, Modernising Medical Microbiology and Big Infection Diagnostics, Obesity, Diet and Lifestyle, Partnerships for Health, Wealth and Innovation, Preventive Neurology, Surgical Innovation, Technology and Evaluation

Leading health researchers in Oxford have been recognised in a prestigious national competition. Eight professors have been named National Institute of Health Research (NIHR) Senior Investigators in recognition of their “outstanding contribution to clinical and applied health and social care ... READ MORE

HIV cure hope thanks to collaboration

4 October 2016 · Listed under Inflammation across Tissues

Researchers are hopeful of a cure for HIV after treating the first patient with a promising new treatment that could kill all traces of the virus. A partnership sparked by the National Institute for Health Research (NIHR) and supported by the NIHR Oxford Biomedical Research Centre is behind this ... READ MORE

Treatment targets HIV’s last hiding place

14 July 2016 · Listed under Inflammation across Tissues, Other News

Picture: Wellcome Trust UK scientists may have found a way to destroy HIV's last refuge. A study by Oxford University has confirmed that a treatment developed by a British company can remove the virus in its chosen hiding place, in laboratory conditions, offering hope of a viable ... READ MORE

15 Research Themes