A three-year NIHR Oxford Biomedical Research Centre (BRC) citizen science research study looking at treatments for non-alcoholic fatty liver disease (NAFLD) entered its final stages with a final visit from a European evaluation team. The study by the Oxford BRC and the Oxford Centre for ... READ MORE
Researchers cast the net widely for atrial fibrillation trial
An Oxford trial to detect atrial fibrillation has been designed to include as many eligible people as possible, including those who rarely interact with the healthcare system or take part in clinical trials. Working with 27 general practice surgeries, the AMALFI study, which is funded by the ... READ MORE
Study assesses long-term risk of invasive breast cancer after pre-invasive disease
A new study has provided evidence that women who have been diagnosed with ductal carcinoma in situ (DCIS) outside the NHS breast screening programme are around four times as likely to develop invasive breast cancer and to die from breast cancer than women in the general population. The study by ... READ MORE
Researchers develop easy-to-deploy federated learning system that safeguards patient data
Researchers in Oxford have developed a new, easy-to-use technique for hospitals to contribute to the development of artificial intelligence (AI) models, without patient data leaving the hospital’s premises. The technique, which builds on recent advances in decentralised machine learning, uses ... READ MORE
Trial studies inhalation of TB vaccine
A new clinical trial has been launched in Oxford to determine the effectiveness of delivering tuberculosis (TB) vaccines through inhalation. The study is being conducted by researchers at the University of Oxford’s Jenner Institute, who are giving BCG, the current licensed vaccine against ... READ MORE
Study highlights importance of ‘junk’ DNA in unlocking diagnosis
A new academic paper has revealed that areas of the human genome that are routinely overlooked in clinical tests may be the cause of some rare diseases. Assessing 122 patients with genetic conditions including rare forms of heart arrhythmia, brain inflammation, inflammatory bowel disease and ... READ MORE
New NIHR Oxford Senior Research Fellows named
Researchers from a wide range of disciplines have been appointed to be the next cohort of NIHR Oxford Senior Research Fellows – seven mid-career researchers identified as having the potential to become future translational research leaders. As in previous years, the selection ... READ MORE
Vaccine trial for deadly Nipah virus launched
The first participants have received doses of a new vaccine against Nipah virus in a clinical trial by University of Oxford researchers. Nipah virus is a devastating disease mostly found in South-East Asia that can be fatal in up to 75 percent of cases. This first-in-human trial of the vaccine ... READ MORE
COVID-19 vaccines found effective in reducing long COVID symptoms
A research team at the University of Oxford has found that vaccination against COVID-19 consistently reduced the risk of long COVID symptoms. While vaccines have proved effective in preventing severe COVID-19, their ability to prevent long-term symptoms has not yet been fully ... READ MORE
Oxford BRC-funded paper named BMJ UK Research Paper of the Year
A study supported by the NIHR Oxford Biomedical Research Centre (BRC) has been named The BMJ UK Research Paper of the Year 2023. The study by researchers at Oxford Population Health into breast cancer mortality rates found that women diagnosed with early-stage breast cancer today are 66% ... READ MORE
Blood collected through skin offers reliable testing method in children with type 1 diabetes
Transdermal sampling - collecting blood through the skin - is a reliable alternative to taking blood samples from a vein with a needle in children with type 1 diabetes (T1D), new research has found. The study by Oxford researchers is the first to test the acceptability of transdermal sampling ... READ MORE
Oxford Vaccine Group receives £7.8m in research funding to fight pandemic threats
The Oxford Vaccine Group (OVG), which led the rapid clinical development of the Oxford vaccine in COVID-19 in the pandemic, has been awarded £7.8 million by UK Aid for research into the prevention of five dangerous diseases with epidemic or pandemic potential. The awards will fund research into ... READ MORE
Blood test developed to identify those at risk of developing Parkinson’s
Research carried out at the University of Oxford has led to the development of a new blood-based test to identify the pathology that triggers Parkinson’s disease before the main symptoms occur. This could allow clinicians to screen for those individuals at high risk of developing the disease and ... READ MORE
Small cash incentives improve vaccine uptake in rural areas of Ghana
Researchers from Oxford and Ghana have shown that small cash incentives increased COVID-19 vaccine uptake in rural Ghana. The findings, published in Nature Medicine, could offer a new strategy for enhancing health interventions in Africa. The recent COVID-19 pandemic highlighted the ... READ MORE
“Don’t think ‘someone else can do it’; you need to be that person.”
Research participant profile: Maryam Masood was diagnosed with ulcerative colitis at the age of 20. But that had followed three years of symptoms and uncertainty about what was causing them. She is now taking part in research trials supported by the NIHR Oxford Biomedical Research Centre (BRC), ... READ MORE
Oxford receives European funding for paediatric diabetes research
Oxford researchers have received funding from a European programme to investigate how to best follow up children who are at risk of type 1 diabetes (T1D). Oxford will receive 433,000 euros as part of the EDENT1FI programme which aims to identify T1D at its pre-clinical stage in children in the ... READ MORE
AI tool could help thousands avoid fatal heart attacks
An AI tool that can predict 10-year risk of deadly heart attacks, could transform treatment for patients who undergo CT scans to investigate chest pain, according to research supported by the NIHR Oxford Biomedical Research Centre (BRC). In the first real-world trial of the AI tool, it was ... READ MORE
Heart attack risk decreased in new mothers by self-monitoring blood pressure at home
Self-monitoring blood pressure after giving birth could help to cut new mothers’ risk of future heart disease and strokes, according to new research by Oxford researchers. The study, funded by the BHF and supported by the NIHR Oxford Biomedical Research Centre (BRC), could be the first step ... READ MORE
New insight into immune-pathology in COVID-19 lungs
A study by Oxford researchers has provided new insights into how immune cells interact in the lungs of patients with severe COVID-19. In a damaged lung with a massive cell infiltrate, as seen with severe COVID-19 infection, it can be difficult to determine which cells are involved in ... READ MORE
Partnership with Danaher paves way for precision medicine test for sepsis
The University of Oxford today announced a partnership with Danaher Corporation to develop a new test to enable precision medicine care for sepsis, a pathological immune response to infection that accounts for one in five deaths globally each year. The test will build on research from the ... READ MORE
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