A University of Oxford team has been awarded a grant to study one of the major unsolved questions about asthma – why women are more likely to have it than men and why they are twice as likely to die from it. Bioinformatician Dr Emanuele Marchi has received £98,000 from the national charity ... READ MORE
New computational technique reveals changes to lung function after COVID-19 infection
A study led by Oxford researchers has found that prior COVID-19 infection is associated with more uneven inflation of the lungs during normal breathing. There was also an association between hospitalisation with COVID-19 and smaller lung volumes, and admission to the intensive care unit (ICU) was ... READ MORE
One in eight people have undiagnosed nighttime hypertension
Around 15 percent of people aged between 40 and 75 may have a form of undiagnosed high blood pressure (hypertension) that occurs only at nighttime. Because they do not know about this, and are therefore not being treated for it, they are at a higher risk of cardiovascular disease such as ... READ MORE
Next generation of research leaders complete BRC programme
Aspiring healthcare research leaders have successfully completed the latest Oxford BRC Next Generation Leaders Programme, with the 16 course participants presenting the quality improvement projects they had been working on. This is the third edition of the Next Generation Leaders Programme, ... READ MORE
Malaria booster vaccine continues to meet WHO efficacy goal
Researchers from the University of Oxford and their partners have reported new findings from their Phase 2b trial which tested the effectiveness of a booster dose of their candidate malaria vaccine. The vaccine, R21/Matrix-M, had previously demonstrated high-level efficacy of 77 ... READ MORE
OUH clinical staff awarded funding for research skills training
OUH clinical staff awarded funding for research skills training Thirteen Oxford University Hospitals (OUH) nurses, midwives, allied health professionals and research practitioners have received funding to develop skills that will support them to research new and improved ways of delivering ... READ MORE
OUH nurse researcher gets award to further study
A Clinical Academic Nurse Researcher at Oxford University Hospitals (OUH) has been given an award by the British Federation of Women Graduates (BFWG) to continue her research exploring how to improve the escalation of care for patients whose condition deteriorates in the hospital setting. Jody ... READ MORE
Study raises hope of pre-school type 1 diabetes screening programme
Researchers in Oxford have launched the first UK study in the general population to test for early markers of type 1 diabetes before children develop symptoms or need insulin. The study, which is being offered when children have their pre-school vaccination, involves a finger prick and a few ... READ MORE
Study develops radiotranscriptomic AI analysis to enable virtual heart biopsies
Oxford University researchers have found a new way of directly quantifying vascular inflammation in COVID-19 patients, in a study that could pave the way to more efficient trials of new treatments and identify patients who might be at risk of long-term complications. The study, which was ... READ MORE
Higher risk of blood clots in COVID-19 outpatients, largely reduced after vaccination
Researchers supported by the NIHR Oxford Biomedical Research Centre (BRC) have studied the link between people diagnosed with COVID-19 as outpatients and the short-term risk of developing blood clots, and the clinical and genetic risk factors that predispose them to developing post–COVID-19 ... READ MORE
Environmental impact of 57,000 multi-ingredient processed foods revealed for first time
New analysis provides a first step towards enabling consumers, retailers, and policymakers to make informed decisions on the environmental impacts of multi-ingredient food and drink products. Recent surveys indicate that over half of UK consumers want to make their diets more sustainable, and ... READ MORE
£1.2m award to improve diagnosis of emergency spinal condition
The National Institute for Health and Care Research has awarded an Advanced Fellowship to Oxford University Hospitals (OUH) emergency medicine doctor David Metcalfe to study the diagnosis of the spinal condition cauda equina syndrome. Cauda equina syndrome is caused when the nerves at the end of ... READ MORE
Workshop helps public contributors become ‘citizen experts’ on equality and diversity in research
Members of the public who are involved in health research in Oxford have attended a training workshop focused on the ways in which equality, diversity and inclusion (EDI) can help improve the quality of research and its relevance to society as a whole. The workshop aimed to increase delegates’ ... READ MORE
Oxford receives major BHF award to research cure for inherited heart diseases
An injectable cure for inherited heart muscle conditions that can kill young people in the prime of their lives could be available within a few years, after an international team of researchers were announced as the winners of the British Heart Foundation’s (BHF) Big Beat Challenge. The BHF ... READ MORE
BRC funds study to test anti-TNF drugs on post-operative delirium
University of Oxford researchers have been awarded a grant from the National Institute for Health and Care Research (NIHR) to investigate whether anti-tumour necrosis factor (TNF) therapy can reduce or prevent delirium following surgical operations. Post-operative delirium is an important ... READ MORE
Gene variant links trigger finger and carpal tunnel syndrome
A study by University of Oxford researchers has found a genetic variant that increases the risk of both carpal tunnel syndrome and trigger finger, and opens the door for potential new therapies. The study, which was supported by the NIHR Oxford Biomedical Research Centre (BRC), was published in The ... READ MORE
Moderate drinking linked to brain changes and cognitive decline
Consumption of seven or more units of alcohol per week is associated with higher levels of iron in the brain, according to a study by Oxford researchers. Accumulation of iron in the brain has been linked with Alzheimer’s and Parkinson’s diseases and is a potential mechanism for alcohol-related ... READ MORE
OUH dietitian accepted onto NIHR pre-doctoral fellowship
An Oxford University Hospitals (OUH) dietitian specialising in adult cystic fibrosis has been awarded a national pre-doctoral fellowship, following career support from the Oxford Biomedical Research Centre (BRC). Joanna Snowball (pictured), who works in the Oxford Adult Cystic Fibrosis (CF) ... READ MORE
Human trials of aerosol-based TB vaccine begin
University of Oxford researchers have begun recruiting for a phase I clinical trial of a tuberculosis vaccine in human volunteers to develop a new way to test the efficacy of future TB vaccines. The study is led by the Director of the NIHR Oxford Biomedical Research Centre (BRC), Helen McShane, ... READ MORE
Researchers learn how to involve diverse communities in their research
On 21 June, around 30 Oxford researchers and 12 public contributors came together at Oxford’s Old Fire Station to discuss ways of involving people from diverse communities in health research. Health researchers want to engage with people from these communities so that their research is more ... READ MORE
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