A study led by Oxford researchers has found that the drug vedolizumab can induce remission in patients who have chronic pouchitis after surgery for ulcerative colitis. Twelve percent of people with ulcerative colitis need surgery to have their colon removed. Most have an ileo-anal pouch ... READ MORE
News Archive
New approach to nail bed injury surgery could cut NHS costs
A new Oxford study, supported by the NIHR Oxford Biomedical Research Centre, shows that changing clinical practice for finger injuries in children could save the NHS £720,000 per year. Nail bed injuries in children are very common. They are generally caused by a child crushing their fingertip in ... READ MORE
Prostate cancer AI diagnosis tool begins evaluation in Oxford
New artificial intelligence software that can help to spot prostate cancer is being trialled by researchers at Oxford University Hospitals (OUH) NHS Foundation Trust Researchers and clinicians in Oxford have begun an evaluation of artificial intelligence (AI) software that could help ... READ MORE
Nursing and midwifery research lead appointed to national programme
Oxford University Hospitals’ (OUH) Director of Nursing and Midwifery Research and Innovation, Professor Helen Walthall, has been appointed onto a national programme aimed at embedding a culture of research amongst nurses and midwives. Professor Walthall (pictured, right) was appointed as a ... READ MORE
Professor Barbara Casadei named NIHR Senior Investigator
The Oxford BRC’s Theme Lead for Cardiovascular Medicine, Professor Barbara Casadei, has been named a National Institute of Health and Care Research (NIHR) Senior Investigator, while three other Oxford BRC researchers have been reappointed to this prestigious position in recognition of ... READ MORE
Citizen scientists invited to help tackle antibiotic resistance
A research team in Oxford has launched a new project involving members of the public that is aimed at developing diagnostics for infection and antibiotic resistance. The team of physicists, microbiologists, data scientists and doctors, who are supported by the NIHR Oxford Biomedical Research ... READ MORE
Bioelectronic implant offers intelligent therapy to treat incontinence
The first participants in a clinical trial of a bioelectrical therapy to treat incontinence have received their 'smart' bioelectronic implants. Amber Therapeutics, a University of Oxford spin-out company developing intelligent bioelectrical therapies, applied the Picostim-DyNeuMo research ... READ MORE
An open book? New genetic mutation linked to rare conditions
Researchers have discovered that a rare type of genetic variant can be responsible for two well-known skeletal disorders. Whereas many genetic conditions are caused by structural variations that involve deletions, insertions or duplications of segments of DNA, the scientists found that the ... READ MORE
Oxford BRC to be given Freedom of Oxford
The NIHR Oxford Biomedical Research Centre (BRC) is to be given the Freedom of the City of Oxford. The award is the highest honour Oxford City Council can bestow and has previously been given to dignitaries including Oxfam, Nelson Mandela, authors Philip Pullman and Colin Dexter, and Sir Roger ... READ MORE
New imaging centre officially opened
A new Acute Multidisciplinary Imaging and Interventional Centre (AMIIC), based at the John Radcliffe Hospital, has been officially opened. AMIIC, part of the University of Oxford’s Radcliffe Department of Medicine, was previously known as AVIC (Acute Vascular Imaging Centre). The newly ... READ MORE
National guidelines produced on use of genomics in treatment of IBD
National guidelines have been developed for clinicians on the use of genomics to diagnose and care for patients with monogenic inflammatory bowel disease (IBD), a group of intestinal disorders caused by variations in a single gene. The new guidelines, unveiled in an article in the Lancet ... READ MORE
Better diagnosis and treatment of autoimmune diseases a step closer
A study involving Oxford researchers has outlined a way to find the crucial peptides (protein fragments) that drive autoimmunity, as well as the immune cells that respond to it. On a fundamental level, in autoimmune diseases immune cells mistake healthy cells for infected cells. Finding the ... READ MORE
Professor Marian Knight recognised for services to maternal and public health
Professor Marian Knight, the Oxford Biomedical Research Centre’s Co- Theme Lead for Cardiovascular Medicine, has been recognised in the New Year Honours list 2023. She was appointed Member of the Order of the British Empire (MBE) for services to Maternal and Public Health. Professor ... READ MORE
Genetic ‘marker’ linked to side-effects from skin cancer treatment found
New research has identified a genetic marker that could be used to predict a patient’s risk of developing serious side-effects when undergoing immunotherapy treatment for one of the most common skin cancers. The study, which was supported by the NIHR Oxford Biomedical Research Centre ... READ MORE
No benefit found in switching to citrate anticoagulation for ICU kidney injury treatment
New research has found no added benefit of using citrate-based drugs in the treatment of acute kidney disease in intensive care, when compared to the anticoagulation drug heparin, despite their extra cost. People with acute kidney injury (when the kidneys stop working correctly) may need a ... READ MORE
Adalimumab found to be cost-effective treatment for early-stage Dupuytren’s disease
Oxford researchers supported by the Oxford BRC have found that the anti-TNF treatment adalimumab is likely to be a cost-effective treatment for people affected by early-stage Dupuytren’s disease. Anti-TNF treatments interfere with the action of a protein called tumour necrosis factor (TNF) and ... READ MORE
Patient and public involvement contributors prepare for launch of new BRCs
Patient and public contributors have gathered with researchers in Oxford to discuss how patient and public involvement and engagement (PPIE) can be enhanced and play a bigger role in the new NIHR Biomedical Research Centres (BRC) when they begin next month. The workshop at St Catherine’s ... READ MORE
Oxford researcher investigates genetic mechanisms of rare forms of asthma
An Oxford researcher has been awarded funding to expand her cutting edge research into the genetic mechanisms of rare and severe forms of asthma. Dr Anastasia Fries, NIHR Academic Clinical Fellow in Respiratory Medicine, was awarded a three-year MRC Clinical Research Training Fellowship worth ... READ MORE
BRC sponsors Black History Month talk by anti-apartheid veteran
The Oxford Biomedical Research Centre has sponsored a talk organised a talk by Oxford University Hospitals BAME network as part of Black History Month. The talk on Wednesday 12 October was by Chris Lubbe, anti-apartheid activist and former bodyguard of the late South African President Nelson ... READ MORE
Oxford BRC gets £86.6m funding for healthcare research
Health and care research in Oxford is to receive £122 million in government funding over the next five years to improve diagnosis, treatment and care for NHS patients. The funding was awarded to the city’s two National Institute for Health and Care Research (NIHR) Biomedical Research Centres ... READ MORE
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