Professor Sarah Pendlebury, from the NIHR Oxford BRC’s Preventive Neurology Theme, and Dr Aubretia McColl, of the Wolfson Centre for Prevention of Stroke and Dementia, explain how they have tackled the challenge of recruiting older, frail patients with multiple conditions to trials within ... READ MORE
News
Dr Clement Twumasi – underpinning our research with statistical expertise
Dr Clement Twumasi is an Oxford BRC-supported medical statistician whose role involves providing a range of statistical support for clinical trials and other vaccine-related studies, as well as assisting with funding applications. Based at the University of Oxford’s Nuffield Department of ... READ MORE
Study reveals previously unknown genetic causes of colorectal cancer
A pioneering study has provided the most comprehensive analysis to date of the genetic make-up of colorectal cancer. The study, which was supported by the NIHR Oxford Biomedical Research Centre, involved the Universities of Oxford, Manchester, Birmingham, Edinburghand Leeds, The Institute of ... READ MORE
UK’s most ambitious melanoma research study created for patients, by patients
“Any melanoma patient can be part of it. You don’t have to go into a hospital, you don’t have to live near a university that’s active in research, all you need is access to the internet.” Kelly Norman, patient representative MyMelanoma is an online-based research project for melanoma ... READ MORE
Research identifies autoimmunity against a key anti-inflammatory regulator in IBD
A ground-breaking study has identified a new disease-inducing mechanism for inflammatory bowel disease (IBD) in which the immune system attacks its own regulatory function. Interleukin-10 (IL10) is an anti-inflammatory protein that crucially controls intestinal immunity. Children with genetic ... READ MORE
Prediction model could help inform patients of shoulder replacement surgery risks
A new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between researchers from Oxford, Bristol and Copenhagen. The model could be an important tool to help patients and doctors make more informed decisions about this common ... READ MORE
Patient story – Kathryn Hedigan, EXPLAIN study
Kathryn Hedigan took part in the EXPLAIN study, which used hyperpolarised xenon MRI scans to investigate possible lung damage in long COVID patients who had not been hospitalised with COVID-19 but who continued to experience breathlessness. Kathryn, aged 66, lives near Burford in West ... READ MORE
Workshop explores CRISPR gene editing potential
The NIHR Oxford BRC’s Gene and Cell Therapy Theme has organised its second workshop to discuss how researchers from a range of disciplines are using new CRISPR gene editing tools or applying CRISPR to their research in innovative ways. The workshop, held on 4 July at Merton College in Oxford, ... READ MORE
Glowing dye helps surgeons eradicate prostate cancer
A glowing marker dye that sticks to prostate cancer cells could help surgeons to remove them in real-time, according to new research. Scientists at the University of Oxford and Oxford University Hospitals NHS Foundation Trust, supported by Cancer Research UK and the NIHR Oxford Biomedical ... READ MORE
Viagra drug improves brain blood flow and could help to prevent dementia
A University of Oxford trial has shown that sildenafil, commonly known as Viagra, enhances blood flow to the brain and improves the function of brain blood vessels in patients at a heightened risk of vascular dementia. This new study, published in Circulation Research and supported ... READ MORE
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