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Research Theme

Modernising Medical Microbiology and Big Infection Diagnostics

Home > Research Themes Overview > Modernising Medical Microbiology and Big Infection Diagnostics > Infections in Oxfordshire Research Database > IORD Projects > Outcomes after elective surgery: prognostic information in baseline blood tests

IORD Project

Outcomes after elective surgery: prognostic information in baseline blood tests

COMPLETED
IORD category: Electronic Health Records
Chief Investigator: Dr David Wyllie
Sponsor: OUH
Research location: OUH NHS Trust
Approval date: 04 Jul 2014

Although relatively rare (under 5%), surgical site infections are the most common complication of planned operations (hospital admissions for what is termed “elective surgery”). Other complications (such as needing to be re-operated on, or even dying) are also rare, but may also be related to underlying infections, even when these cannot be directly identified by growing micro-organisms from patient samples. These complications cause ill-health and are extremely distressing for patients. Some predictors of complications are known – for example, making sure patients glucose levels remain in normal ranges, and that they do not get too hot or too cold reduces the risk of complications. However, recent studies in other infections including tuberculosis and malaria suggest that the relative numbers of some different types of blood cells might also be related to poor outcomes. We want to find out whether these blood cell values could also be a predictor of complications following planned operations, and whether this could be a useful way to identify patients at high risk, who could then be managed more intensively to reduce complications.

Modernising Medical Microbiology and Big Infection Diagnostics

  • Modernising Medical Microbiology and Big Infection Diagnostics
  • Sub-theme 1: Novel rapid, high-throughput diagnostic workflows for infection
  • Sub-theme 2: Big data-led infection diagnosis and management strategies
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