NIHR Oxford Biomedical Research Centre

Enabling translational research through partnership

MENUMENU
  • About
    • About the NIHR Oxford Biomedical Research Centre
    • Activities during COVID-19
    • Strategic Partnership Board
    • Steering Committee
    • Promoting Equality, Diversity and Inclusion in Research
    • Current Vacancies
    • Contact Us
    • Stay in Touch
  • Research
    • Research Themes Overview
    • Cancer
    • Cardiovascular Medicine
    • Digital Health from Hospital to Home
    • Gene and Cell Therapy
    • Genomic Medicine
    • Imaging
    • Inflammation across Tissues
    • Life-saving Vaccines
    • Metabolic Experimental Medicine
    • Modernising Medical Microbiology and Big Infection Diagnostics
    • Musculoskeletal
    • Preventive Neurology
    • Respiratory Medicine
    • Surgical Innovation, Technology and Evaluation
    • Translational Data Science
  • Patient & Public Involvement
    • Getting involved with research
    • View and register for involvement opportunities
    • Patient & Public Groups
    • Patient and Public Involvement Advisory Group
    • Diversity in Research Group
    • Oxford Blood Group
    • Case Studies
    • PPIE Strategy
    • PPIE News
    • PPI Researcher Guidance
    • Researchers: Post a PPIE opportunity
  • Training Hub
    • Training Hub Overview
    • Clinical Academic Pathway
    • Internships
    • Preparatory Research Fellowships
    • Senior Research Fellowships
    • Research Training Bursaries
    • Doctoral Awards
    • Post-Doctoral Awards
    • Other funding
    • Leadership Training
    • Useful Links
    • Training and Education Resources
    • Upcoming Training Events & Courses
  • Industry
    • Collaborate with Oxford BRC
    • Who Do We Work With?
    • Events
    • Further Information and Additional Resources
    • Contacts for Industry
  • Videos
  • News
  • Events
Research Theme

Modernising Medical Microbiology and Big Infection Diagnostics

Home > Research Themes Overview > Modernising Medical Microbiology and Big Infection Diagnostics > Infections in Oxfordshire Research Database > IORD Projects > Covid-19 seroprevalence in inflammatory bowel disease patients on maintenance biological therapy: a comparison with healthcare workers

IORD Project

Covid-19 seroprevalence in inflammatory bowel disease patients on maintenance biological therapy: a comparison with healthcare workers

ONGOING
IORD category: COVID-19
Chief Investigator: Professor Jack Satsangi
Sponsor: OUH
Research location: Oxford University
Approval date: 18 Oct 2020

The inflammatory bowel diseases (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) affect approximately 1% of the UK population; and 25-30% of these patients are now treated with biological therapies which target the immune system to maintain remission.

It has been hypothesized that these patients may be at increased risk of either clinically apparent SARS-CoV-2 infection (Covid-19), or sub-clinical infection.

As part of a separately approved project, we are following a cohort of patients who will be attending regularly for the biological agents infliximab or vedolizumab to assess who becomes infected with SARS-CoV-2 and develops symptoms, as well as using blood tests to see who develops antibodies to the virus.

Data from SARS-CoV-2 antibody testing of healthcare workers in Oxfordshire are held within IORD. We would like to use IORD data to compare rates of antibody detection in patients with IBD from our cohort and those in healthcare workers.

Modernising Medical Microbiology and Big Infection Diagnostics

  • Modernising Medical Microbiology and Big Infection Diagnostics
  • Sub-theme 1: Novel rapid, high-throughput diagnostic workflows for infection
  • Sub-theme 2: Big data-led infection diagnosis and management strategies
  • Infections in Oxfordshire Research Database (IORD)
    • IORD Projects
  • Contacts
  • Videos
  • News

Subscribe to the Oxford BRC Newsletter

Keep informed about the work of the Oxford BRC by subscribing to our Mailchimp e-newsletter. It is produced several times a year and delivers news and information about upcoming events straight to your inbox.

Subscribe Now

Oxford BRC on Social Media

  • Facebook
  • LinkedIn
  • Twitter
  • YouTube

Feedback

We’d love to hear your feedback. Please contact us at obrcenquiries@ouh.nhs.uk

  • Data Control and Privacy
  • Accessibility
  • Our Partners
  • Disclaimer
  • Contact

Copyright © 2023 NIHR Oxford Biomedical Research Centre