One of the most important factors influencing the success of IVF treatment is the health of the embryo selected for transfer to the womb. Approximately 85 per cent of all embryos transferred do not ultimately go on to produce a baby. In recent years the importance of counting chromosomes in the ... READ MORE
News for Genomic Medicine
100,000 Genomes Project video online
A talk on a pioneering genetics project being led in the Thames Valley by Oxford University Hospitals NHS Trust is now available to view online. Director of the Oxford NHS Genomic Medicine Centre and Associate Professor of Molecular Diagnostics for the University of Oxford’s Department of ... READ MORE
Blog: 100,000 Genomes Project will help people for generations to come
By Dr Angela Hamblin, Molecular Diagnostic Research Fellow at the NIHR Oxford Biomedical Research Centre The wait is over! The Oxford NHS Genomic Medicine Centre is now the first centre in the country open to recruit patients with cancer into Genomics England’s 100,000 Genomes Project. This ... READ MORE
Recruitment begins on major genetics project
A project to unravel the genetic changes underlying rare disease and cancers of more than 1,200 patients and their families who are looked after by Oxford University Hospitals NHS Trust (OUHT) has started. The project will aid research, improve diagnosis and ultimately clinical outcomes so NHS ... READ MORE
New TB test to get sufferers on right drugs sooner
Tuberculosis sufferers will be able get drug treatment sooner thanks to a new whole genome sequencing technique to determine for the first time which drugs to give sufferers, researchers in Oxford have reported. University of Oxford researchers at the John Radcliffe Hospital have developed a ... READ MORE
Project brings Whole Genome Sequencing into the clinic
More than 10 years after the completion of the Human Genome Project doctors are a step closer to using whole genome sequencing to diagnose and treat patients with genetic diseases. This follows a study by researchers from the University of Oxford and the DNA sequencing company Illumina. Results ... READ MORE
Gene sequencing test for cancer patients on the NHS
The first multi-gene DNA sequencing test that can help predict cancer patients’ responses to treatment has been launched in the National Health Service (NHS), thanks to a partnership between scientists at the University of Oxford and Oxford University Hospitals NHS Trust. The test uses the latest ... READ MORE
New understanding of craniosynostosis will help families and treatment centres
RESEARCHERS in Oxford have discovered two new genetic causes of craniosynostosis - a rare bone condition that can inhibit brain growth in children. The work will give affected families much greater understanding of the condition and inform patient treatment plans. Andrew Wilkie, Nuffield ... READ MORE
TB’s genetic “family tree” may hold the key to tackling outbreaks quickly and effectively
NEW genetic sequencing techniques can map the “family tree” of a Tuberculosis (TB) outbreak allowing the spread of disease to be tackled quickly and effectively. Researchers, led by the NIHR Oxford Biomedical Research Centre, the Health Protection Agency in Birmingham and the Wellcome Trust ... READ MORE
Gene therapy trial begins for blindness caused by choroideraemia
Professor Robert MacLaren from the University of Oxford and Professor Miguel Seabra from Imperial College London are undertaking a clinical trial using gene therapy to treat a disease that causes blindness known as choroideraemia. This condition is currently incurable and affects thousands of people ... READ MORE
Man treated in Oxford for blindness with gene therapy
Researchers in Oxford have treated a man with an advanced gene therapy technique to prevent him from losing his sight. It is the first time that anyone has tried to correct a genetic defect in the light-sensing cells that line the back of the eye. The president of the Academy of Medical ... READ MORE
Heart disease linked to a few rogue genes
Heart disease is linked to just a few rogue genes as well as lifestyle choices, landmark research into Britain’s biggest killer has found. The 18 genes that raise the risk of cardiac problems, from heart attacks to hardening of the arteries, have been pinpointed in three studies involving ... READ MORE
NHS laboratory to pilot next-generation genetic sequencing
Dr Andrea Nemeth, Consultant Clinical Geneticist and Honorary Senior Lecturer at Oxford's Churchill Hospital and the University of Oxford, is part of a team that is currently testing two next-generation sequencing platforms - the Roche 454 and Illumina systems - for use in a hospital ... READ MORE
Additional investment in high through-put sequencing
The Medical Research Centre (MRC) is pleased to announce an additional investment in high-throughput sequencing that will bring funding of hubs for high-throughput sequencing to more than £9 million. The new hub will be based in Oxford and adds to the previously announced hubs in Scotland, the ... READ MORE