Researchers at the University of Oxford have published new research that shows that by the end of May there had been about 5,000 fewer hospital admissions with heart attack in 2020 than would be expected, suggesting that many patients have missed out on lifesaving treatment. The research showed ... READ MORE
News for Translational Data Science
Varying risk of COVID-19 to health workers revealed
A study at Oxford University Hospitals (OUH) NHS Foundation Trust has revealed the different levels of risk faced by healthcare workers dealing with the COVID-19 pandemic. In a major collaboration with the University of Oxford, almost 10,000 staff were tested both for presence of the virus ... READ MORE
Breakthrough in RECOVERY COVID-19 drug treatment trial
A cheap and widely available steroid has been found to save lives of patients hospitalised with COVID-19 in a national trial being led by University of Oxford researchers. Dexamethasone was one of the drugs being tested as part of the RECOVERY trial, the world's biggest trial looking at whether ... READ MORE
Study sheds light on breast cancer risk after pre-invasive disease
Women who are diagnosed with ductal carcinoma in situ (known as DCIS) during breast screening go on to experience higher risks of developing breast cancer and of death from breast cancer, compared with the general population, according to a study by Oxford researchers. DCIS is a disease where ... READ MORE
Large-scale COVID-19 infection and antibody test study launched
Some 20,000 households across England are being contacted to take part in the first wave of a major new government study to track the COVID-19 coronavirus in the general population. The study will help improve understanding around the current rate of infection and how many people are likely to ... READ MORE
Oxford-led research describes the safety profile and potential harms of hydroxychloroquine and azithromycin
Over 300 researchers from the Observational Health Data Sciences and Informatics (OHDSI) international community studied data from almost 1 million patients who have previously taken hydroxychloroquine. They declared hydroxychloroquine safe for short-term use, but urge caution in using it in ... READ MORE
GP practices urged to join COVID-19 research
Oxford researchers have launched a study to track the spread of COVID-19 in the population and develop a deeper understanding of the virus in general practice. The University of Oxford’s Nuffield Department of Primary Care Health Sciences (NDPCHS) and the Royal College of General Practitioners ... READ MORE
Oxford researchers to play key role in fight-back against COVID-19
Researchers supported by the NIHR Oxford Biomedical Research Centre will play a crucial role in tackling the current COVID-19 pandemic, ranging from the development of a new vaccine to developing the most effective drug treatments for people who have contracted the virus. A team from the ... READ MORE
Heart failure care must address patients’ broader health if survival rates are to improve
Oxford BRC-supported researchers have provided new evidence that might explain why the prognosis of heart failure patients has improved so little over the past decade. Findings show that a decline in cardiovascular deaths has been offset by an increase in the number of deaths from infections and ... READ MORE
Achieving Type 2 diabetes treatment targets would improve health and reduce healthcare costs
Improvements in health and reductions in healthcare costs could be achieved if blood glucose, blood pressure and cholesterol treatment targets were met. Researchers from the Nuffield Department of Population Health, University of Oxford, assessed the long-term impact of achieving treatment ... READ MORE
Clinical data project leads to potential advance in understanding of chronic hepatitis B
Researchers and clinicians in Oxford have provided fresh insights into how some people with chronic hepatitis B (CHB) can be cleared of the disease, as part of a national initiative to better use NHS patient data to tackle emerging health issues. It is hoped that the research, the first study on ... READ MORE
Stroke deaths in England halved in ten years, study finds
Deaths from stroke in England halved in the first 10 years of the 21st Century, thanks to improved treatment, a study by Oxford BRC-funded researchers has found. However, the study, published in the BMJ, warned that there had been an increase in the number of people under the age of 55 who had ... READ MORE
Women and older people most likely to experience shortcomings in heart failure care
A study of 93,000 UK adults with heart failure has revealed critical care shortcomings in diagnostic tests, drug prescriptions, and follow-up patterns, with women and those over 75 years of age disproportionately affected. The study by The George Institute for Global Health at the University of ... READ MORE
NIHR Oxford BRC Senior Research Fellows named
The Oxford BRC is delighted to announce the appointment of seven new Senior Research Fellows. They were chosen from an extremely strong field of 47 applicants from across the scientific and clinical community because they demonstrated that their research was high impact and of high quality . ... READ MORE
New project to accelerate clinical trial recruitment
A new project, led by the University of Oxford, will use NHS data to accelerate recruitment into clinical trials and increase the opportunities for NHS patients to participate in research. Every NHS hospital keeps a detailed record of activities. A monthly report is sent to NHS Digital, who ... READ MORE
Concerns raised as opioid prescriptions rise across UK
Researchers supported by the NIHR Oxford Biomedical Research Centre(BRC) have recommended greater action to promote best practice, as a new study revealed a rise in prescriptions of opioids for treating chronic pain over thepast 20 years. The research reviewing opioid prescribing, published in ... READ MORE
Genetic changes associated with physical activity emerge thanks to machine learning pioneers
Time spent sitting, sleeping and moving is determined in part by our genes, University of Oxford researchers have shown. In one of the most detailed projects of its kind, the scientists studied the activity of 91,105 UK Biobank participants who had previously worn an activity monitor on ... READ MORE
Study reveals trends in incidence of spontaneous pneumothorax
Oxford researchers supported by the NIHR Oxford Biomedical Research Centre have published research that show how the rates of incidence and recurrence of spontaneous pneumothorax have changed over time. The research, published on 9 October in the Journal of the American Medical Association, ... READ MORE
Oxford team use DNA sequencing and patient data to halt infection outbreak
Clinical and research teams at Oxford University Hospitals (OUH) NHS Foundation Trust, using infection prevention and control best practice, whole genome sequencing and electronic patient data, have halted an outbreak of a potentially deadly fungal pathogen after detecting that multi-use patient ... READ MORE
Research for better shared decision-making in knee surgery
New research by a team at the University of Oxford, supported by the NIHR Oxford Biomedical Research Centre, provides a robust basis for informed shared decision-making and consent on keyhole knee surgery. An innovative study, published today in the Lancet, using 20 years’ worth of data covering ... READ MORE
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