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Analysis of 2009/10 Hospital Norovirus outbreak
COMPLETED
IORD – Ongoing approved projects and project outputs
C. difficile testing specificity in Oxfordshire 1997-2009
COMPLETED
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C. difficile transmission in Oxfordshire hospitals 2006-2009
COMPLETED
Summary of findings: In an endemic setting, with well-implemented infection control measures, ward-based contact with other patients with C. difficile diarrhoea cannot account for the majority of new cases – no more than 25% of new cases in Oxfordshire over 2 years could be linked to a previous ... READ MORE
Incidence of and competition between different pathogens isolated from blood and other sterile sites in Oxfordshire 1997-2009
COMPLETED
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Competition between MRSA and MSSA at an individual level in Oxfordshire 1997-2009
COMPLETED
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MRSA incidence 1998-2009
COMPLETED
Summary of findings: Rates of MRSA infection in blood and other sites were falling before intensification of infection-control measures in 2006. This, together with strain-specific changes in MRSA isolation, strongly suggests that incompletely understood biological factors are responsible for the ... READ MORE
Klebsiella in Oxfordshire 1998-2009
COMPLETED
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Detecting and adjusting for severe illness in inpatients using passively collected data
COMPLETED
See manuscript on The Lancet ... READ MORE
Improving threat detection and quality surveillance: tools for infection management
COMPLETED
Summary of findings: We found that increases in severity of C. difficile diarrhoea, likely to due to the arrival of the hypervirulent 027 strain in the UK, could have been detected three years early using routine monitoring of neutrophil counts at diagnosis, compared with looking at patient ... READ MORE
Infection and mortality in patients with bronchoalveolar lavage/pleural fluid samples
COMPLETED
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Nosocomial MRSA endemicity: addition or replacement (multi-centre, multi-cohort study)
COMPLETED
Summary of findings: Trends in the rates of serious bloodstream infections caused by antibiotic-sensitive microbes were similar between 1998-2007 across 14 hospitals in Europe, but rates of serious bloodstream infections caused by antibiotic-resistant microbes increased much more in hospitals in ... READ MORE