The Diabetes Theme is broad based and its overarching objective is to improve life and patient-important outcomes for people with diabetes mellitus by addressing many aspects of this complex, diverse, common, debilitating and costly condition.
The primary aims of the BRC Diabetes and Metabolism Theme are:
- To understand, preserve and restore normal pancreatic islet and liver function in both type 1 and type 2 diabetes
- To identify biochemical, genetic and genomic biomarkers for both type 1 and type 2 diabetes
- To evaluate novel therapeutics and devices to restore islet and liver function in individuals with type 1 and type 2 diabetes
- To develop translational pipelines to quickly transfer this knowledge into integrated clinical care.
Research across the theme falls into 4 main areas which include;
- Translational Physiology, Therapeutics and Medical Innovation
- Translational Islet and Metabolic Tissue Biology
- Pancreas and Islet Cell Transplantation
- Service Innovation and Evaluation
These sub-themes are supported by core facilities: