NIHR Biomedical Research Centre: Oxford

Enabling translational research through partnership

NIHR 20th Anniversary NIHR website
NIHR Biomedical Research Centre: Oxford
  • Home
  • About
    • About us
    • Impact
    • Our next BRC
    • Steering Committee
    • Promoting equality, diversity and inclusion in research
    • Current Vacancies
    • Stay in Touch
    • Contact Us
  • Research
    • Research Overview
      • NIHR Clinical Research Facility
      • Ethics in the NIHR BRC: Oxford
      • Health Economics
      • Medical Statistics
    • Cancer
    • Cardiovascular Medicine
    • Digital Health from Hospital to Home
    • Gene and Cell Therapy
    • Genomic Medicine
    • Imaging
    • Inflammation across Tissues
    • Life-saving Vaccines
    • Metabolic Experimental Medicine
    • Modernising Medical Microbiology and Big Infection Diagnostics
      • Theme overview
      • Infections in Oxfordshire Database (IORD)
    • Musculoskeletal
    • Preventive Neurology
    • Respiratory Medicine
    • Surgical Innovation, Technology and Evaluation
    • Translational Data Science
  • Patient & Public Involvement
    • For patients and the public
    • For researchers
    • More information
  • Training
  • Industry & Partnerships
  • News
  • Events
  • Videos

Research Theme

IORD Project

Changes in the incidence and importance of endocarditis as a diagnosis code in Oxfordshire hospitals

COMPLETED
IORD category: Specific Infections
Chief Investigator: Prof Sarah Walker
Sponsor: OUH
Research location: OUH NHS Trust
Approval date: 21 Jul 2016

In 2008 guidance recommended no longer using antibiotics to prevent people getting infections of the heart after having surgery at their dentists. This was because there was no strong evidence showing this was necessary, and to reduce overall use of antibiotics to avoid increasing antibiotic resistance in future. However, in 2015, a group looked at all admissions to NHS hospitals that had been recorded as being for heart infections. They found that these happened more frequently than would have been expected after the guidance was changed. The problem with these kind of analyses is that it is difficult to be confident about exactly what has caused a specific code to be recorded in a patient’s records. From other studies we know that there have been changes over time in how different diagnostic codes are used, reflecting changes in the way hospitals are managed and paid. We also know that extra codes are used much more frequently now than in the past. We plan to use the extra information about germs grown from patient samples and results of blood tests available in IORD to look in more detail at heart infections in Oxfordshire, and how these may have changed over time.

See publication: ‘Caveat emptor’: the cautionary tale of endocarditis and the potential pitfalls of clinical coding data—an electronic health records study

See also Study shows how Electronic Health Records have to be used carefully, to avoid mistakes in analysing infections, and the bacteria causing them

Modernising Medical Microbiology icon

Modernising Medical Microbiology and Big Infection Diagnostics

  • Theme overview
  • Sub-theme 1: Novel rapid, high-throughput diagnostic workflows for infection
  • Sub-theme 2: Big data-led infection diagnosis and management strategies
  • Contacts
  • Videos
  • News

Infections in Oxfordshire Research Database (IORD)

  • IORD Overview
    • What data is in IORD?
    • Different kinds of data in IORD
    • Who can use the data?
    • How do they get the data?
    • What do they do with the data?
    • What kind of questions has IORD answered? Why is this important?
    • What was it like before IORD?
    • Opting out
  • IORD Application Trajectory
  • IORD Projects
  • IORD Publications
  • IORD Privacy Notice
  • IORD Glossary
  • IORD FAQs
  • IORD Infographics
You are here: Home > IORD > Changes in the incidence and importance of endocarditis as a diagnosis code in Oxfordshire hospitals

Subscribe to the BRC Oxford Newsletter

Keep informed about the work of the BRC Oxford by subscribing to our Mailchimp e-newsletter. It is produced several times a year and delivers news and information about upcoming events straight to your inbox.

Subscribe Now

Feedback

We’d love to hear your feedback. Please contact us at obrcenquiries@ouh.nhs.uk

BRC Oxford on Social Media

  • Bluesky
  • Facebook
  • LinkedIn
  • YouTube
  • Data Control and Privacy
  • Accessibility
  • Our Partners
  • Disclaimer
  • Contact

Copyright © 2026 NIHR Biomedical Research Centre: Oxford