Surgical Innovation and Evaluation — Introduction

Launched in April 2012, the objective of this theme is to establish a platform of multidisciplinary research, encompassing surgical technology innovation from proof-of-principle to large-scale evaluation embedded in the Oxford Surgical Intervention Trials Unit (SITU). Our overarching aim is to improve treatment effectiveness and patient outcomes, through ‘precision surgery’ using molecular targeting, functional imaging, and minimally invasive ablation methods, with reduced side-effects. We will evaluate these techniques and provide evidence required to adopt them in the NHS.

Our aims are to:

1. Establish a new Surgical Intervention Trials Unit (SITU).

2. Use SITU to evaluate surgical innovations including:

i) ablative devices;

ii) device targeted therapies;

iii) organ reconditioning.

iv) per-operative imaging

3. Underpin SITU with imaging technology and biomarker discovery/validation to improve future evaluation tools for surgical innovations.



Our overall vision is therefore to set up a research programme that does not work within one particular disease, but across several different areas, and enables new treatment approaches to be taken from the very first stages to large-scale testing. In time, we should become a national centre for testing advances in surgery.



Our research focuses on 4 sub-themes